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    An inflamed immune system breeds disease and sluggish thinking. Here’s how to cool things down.

    An inflamed immune system breeds disease and sluggish thinking. Here’s how to cool things down. Matter Over Mind: Inflammation And Depression Oh, it’s all in your body.Past studies have shown that there appears to be a correlation between chronic depression and the likelihood of dementia in the later years. Likewise, there are studies which indicate that inflammatory changes in the brain are pathological features of both depression and dementia. These findings have caused rheumatologists to forever be looking over their shoulders: Does the inflammation of the inflammatory diseases rheumatologists treat play a role in depression (and for that matter, dementia)? Perhaps the dysphoria experienced by so many patients with chronic…

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    Fibromyalgia: Mind-Body Disorder

    Fibromyalgia: Mind-Body Disorder August 11, 2011 Question:”I am seeing more and more patients come to my office saying they have fibromyalgia. How should I conceptualize them? Do they have a body disease, or a mind disease?”

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    Depression Raises Women’s Stroke Risk

    Depression Raises Women’s Stroke Risk Study Finds Link Between Depression and Stroke, With Depression Boosting Risk 29% Depression moderately increases a woman’s risk of stroke, according to a new study that confirms earlier research.

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    Half of Parkinson’s Patients With Psychosis Use Antipsychotics

    Despite FDA warnings, no change in overall antipsychotic use in Parkinson’s from 2002 to 2008 The overall use of antipsychotics in Parkinson’s disease (PD) remained unchanged from the 2002 fiscal year (FY) to the 2008 FY, with 50 percent of patients with PD and psychosis (PDP) prescribed an antipsychotic in routine clinical care in the 2008 FY, according to a study published in the July issue of the Archives of Neurology.

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    Are Some Patients Trying to Medicalize Chronic Fatigue

    The findings sounded like good news. As reported recently in The Lancet, chronic fatigue syndrome (CFS) may be successfully treated with a combination of psychotherapy and exercise. Specifically, results of a randomized trial showed that cognitive-behavioral therapy and graded exercise therapy have a moderate effect in the treatment of CFS.1

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    Jury Out on Early Intervention for Psychosis

    There is “emerging, but as yet inconclusive” evidence that individuals in the prodromal phase of psychosis can benefit from early intervention, although whether this will prevent progression to full-blown schizophrenia remains to be seen, conclude the authors of a new Cochrane review. There is also “some support for phase-specific treatment focused on employment and family therapy, but again, this needs replicating with larger and longer trials,” authors Max Marshall, MD, University of Manchester, and John Rathbone, MD, University of Sheffield, United Kingdom, write. The review appears in the latest issue of the Cochrane Library, a publication of the Cochrane Collaboration, an international organization that evaluates medical research. Proponents of early…

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    Car Crash May Precipitate Chronic Pain

    More than one in 10 people in a prospective cohort developed chronic widespread pain over a four-year period — and most of them were involved in a traumatic event during that time, researchers reported. Among those who reported new, widespread chronic pain, 43% said they had experienced a traffic accident, surgery, or broken bones over the same period, according to Gareth Jones, PhD, of the University of Aberdeen in Aberdeen, Scotland, and colleagues. In contrast, only 36% of those who remained pain-free reported such an incident, Jones and colleagues reported online in Arthritis Care & Research. Much of the difference – which approached but did not reach statistical significance —…

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    What Is Fibromyalgia? Medscape Readers Weigh In

    Bret Stetka, MD  “Fibromyalgia is a name in search of a meaning.” -Anonymous Canadian rheumatologist What is fibromyalgia, aside from being a major frustration to patients and clinicians? And what causes it? What Is Fibromyalgia? Introduction Medscape recently published a debate posing these questions to Dr. Charles Argoff, a neurologist specializing in pain, and Dr. Jonathan Kay, a rheumatologist. Tempers flared throughout (respectfully of course), with Dr. Argoff taking the position that fibromyalgia is itself a distinct condition associated with widespread reduction in a patient’s pain threshold, and thus a heightened sensitivity to pain. Dr. Kay held a different view, arguing that fibromyalgia is merely a symptom complex with a…

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    Type 2 diabetes mellitus as a risk factor for the onset of depression: a systematic review and meta-analysis.

    Type 2 diabetes mellitus as a risk factor for the onset of depression: a systematic review and meta-analysis. AIMS/HYPOTHESIS: An earlier meta-analysis showed that diabetes is a risk factor for the development and/or recurrence of depression. Yet whether this risk is different for studies using questionnaires than for those relying on diagnostic criteria for depression has not been examined. This study examined the association of diabetes and the onset of depression by reviewing the literature and conducting a meta-analysis of longitudinal studies on this topic.