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Wellbutrin Withdrawal Symptoms


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I have only been on Wellbutrin SR 100mg for 5 days, and 50mg for 4 days before that. I am finding the increased anxiety unbearable. My question is whether I can stop it cold turkey, since I have been on it for such a short amount of time. My doc says I have not even reached the "therapeutic dose - 200 mg" yet. I am supposed to be titrating up to that today, but I am too terrified because of the non-stop panic symptoms. So, can I just stop it altogeher, without going back down to 50 mg for a week, etc.? Thanks in advance for any advice.

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I have only been on Wellbutrin SR 100mg for 5 days, and 50mg for 4 days before that. I am finding the increased anxiety unbearable. My question is whether I can stop it cold turkey, since I have been on it for such a short amount of time. My doc says I have not even reached the "therapeutic dose - 200 mg" yet. I am supposed to be titrating up to that today, but I am too terrified because of the non-stop panic symptoms. So, can I just stop it altogeher, without going back down to 50 mg for a week, etc.? Thanks in advance for any advice.

You'll have to rely on the recommendation of your mental health specialist for your specific circumstances. That being said, I stopped 300mg after a few months cold turkey, no problems, no objections from my psychiatrist.

My psych has pointed out that bupropion can contraindicated by excessive anxiety, so it's a reason others have backed down to.

I thought "therapeautic dose" varied very much from person to person, and there is no "200mg" rule.

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Withdrawals Or Whats Under The Bandaid?

I just wondered if anyone could help advise me about withdrawal symptoms from wellbutrin?

Im feeling agitated, restless, heightened senses in sound and smell, easily annoyed, slow from thought to speech, cant bare repeating or explaining myself. Feeling strong sense of anger and almost rage throughout my body at times

I don't understand it as there is no reason for any of it. Theres no thought or stress that could make my body and brain react this way.

I was on zoloft 100mg and wellbutrin 450mg and klonapin 2mg before bed for 2 years since a massive car accident in whichni had multiple fractures and a head injury. Im now down to only the 300mg wellbutrin and the 2mg klonapin.

The reason im coming off is because I have done the emotional journey work and in the last 2 years ive been very flat and apathetic. I have no motivation to go anywhere or do anything. As weird as this may sound....I dont feel depressed.

I wanted to come off the meds under the guidance of my psychiatrist, to see where I am in my head.

Is this withdrawals or have I been masking issues over the last 2 years with pills?

I feel like im trapped in someone elses head and body as im not an angry, agitated person. Its like being held prisoner and its so uncomfortable

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...

So you've gone from apathetic to angry, corresponding with titrating down on the meds?

There could be underlying issues, but you're the best person to assess the possibility for that. You may have to just ride it out for a few months until the medication is finally half-lifed out of your system, and after that when your chemistry decides on a new balance point. Whatever your mental health specialist can suggest or recommend would be better-informed than my opinion.

Anyway, if there's one point of real information I can offer, it that's plenty of people here have posted apparent withdrawal side-effects after having been on meds for a while, and these have included altered mental states. Anger, confusion, and crying jags have all been described.

Hope things get better for you soon.

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...

So you've gone from apathetic to angry, corresponding with titrating down on the meds?

There could be underlying issues, but you're the best person to assess the possibility for that. You may have to just ride it out for a few months until the medication is finally half-lifed out of your system, and after that when your chemistry decides on a new balance point. Whatever your mental health specialist can suggest or recommend would be better-informed than my opinion.

Anyway, if there's one point of real information I can offer, it that's plenty of people here have posted apparent withdrawal side-effects after having been on meds for a while, and these have included altered mental states. Anger, confusion, and crying jags have all been described.

Hope things get better for you soon.

Hi

Thank you for replying to me, I really appreciate it.

My psychiatrist has now advised me to take Prozac 20mg whilst tapering off the Wellbutrin (today im on 150mg). I def think its just me reacting to wellbutrin on its own as I used to be on zoloft at the same time.

I've done a huge amount of personal development emotionally and whilst being on the wellbutrin and zoloft ive managed to work through a lot of deep rooted stuff.

It just kept me uninterested in life, which i didnt realize tll over year later i got a car and suddenly realized..'why dont i want to go anywhere'

There could be underlying issues like you say, but i just couldn't withdraw under the wellbutrin without feeling like i was a prisoner in an angry persons head.

ok, so lets see what the prozac does :)

wish me luck and thanks again

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  • 6 months later...

I have been taking 150ml.of Bupropion For three years.Not so much for depression but going through difficult times and have mild adult ADD. My Dr assured me when I was ready to stop..I would not have any problems just stopping.I felt like I didn't really need to be on it any more Within about 2 weeks of stopping abruptly I had a severe attack of vertigo diagnosed as BPPV. I was hospitalized for a day until we could Rule out a stroke or something more serious. I never at the time put the two together..I am 53 very healthy and have never been dizzy in my life. This was unusual in its severity for me..I have gone for therapy at a vertigo clinic which did help.I am now slowly feeling my head on my shoulders like I used to. Thank god it is passing. It has been 5 weeks since it happened. I would assume not stopping gradually may have contributed or maybe just having been on it for 3 years.Im not sure I'll ever know for sure, But if this happens to enough people we will know that this drug has some wild scary consequences regardless of its great reputation for so many various uses. .

Edited by ChloeC
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I stopped 300mg of Wellbutrin XL cold turkey on the advice of a psychiatrist. I already take escitalopram. He said I would have no withdrawal symptoms. He was right! Nothing. Nada. Zip. In fact, I had no side effects when I first started Wellbutrin, no anti-depressant effects from it, and not withdrawal effects. If might as well has been sugar.

It is the only drug I have ever taken that did nothing.

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  • 2 months later...

I just started 150 mg wellbutrin a week ago. I had just tapered off zoloft but don't really think I had tapered off completely. I would like to stop taking wellbutrin. Since it has only been a week do I still need to taper off wb or do you think I could just stop it? Thanks

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  • 2 months later...

I have been on Wellbutrin for a number of years now but decided to wean off, rather sharply too I might add. I was on 300 mg xl and weened down by missing a few doses every other day. I have been off for a couple of weeks now. I have tinnitus pretty bad and have had a few anger rages but I think I'm on the mend. I came off as I tired of being so emotionless and nervous. I am tired now but don't seem to have the restlessness that was driving me crazy. I am on other antidepressants so I am not depressed. I am noticing a little impulsiveness but not sure if that is a withdrawal symptom or not. In either case I think I made a good move to go off this med.

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  • 1 month later...

I started on Bupropion XL 150 mg/day the 12th of Dec. 2014. I was really nervous to take this medicaiton as I have more anxiety issues than depression but my Dr. thought this would be the way to go. I had tried it once a few months ago but only took one dose due to it making my heart pound so hard in my chest I could not relax or sleep. This time when I sarted I took 0.5 mg of Ativan when I got the heart pounding and that helped. I only had to take the Ativan one more time on day three and then seemed to be doing ok. I had alot of side effects with dizziness, nausea, and irritability but was determined to stick with it to see if it would help level me out. I really was not seeing much positive effect from the medicaine other than I was able to fall asleep at night where before I had been having terrible insomnia. By week two I was getting more and more tired during the day and any motivation I might have had was going out the window. Any time I tried to nap during the day however I would barely fall asleep only to wake and would feel worse than I had before. The last two days of taking it I had terrible anxiety and stomach pain from the stress. I stopped it cold turkey on December 31st (took for 20 days). The first day off I was still a little anxious, the next day wasn't too bad but the third day was terrible, I was crying for no reason at all for most of the day, had pain in my chest and no appetite at all, I felt completely depressed and lost. I took brisk walks, tried to stay busy and nothing really helped. It is now evening and I am feeling a little better. My Dr. wants me to start taking Lexapro now and I am really hesitant to start this all over again. I do not however want to have another day like today. Any suggestions would be appreciated.

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Geez. I know how hard it is and how daunting starting a new med that can virtually make you react 100 different ways. And even scarier since you are anxious and scared anyway. I think we all wish there was a blood test or brain scan that would tell us which med was perfect for is.

I want to strongly suggest that you keep trying. You sound like you need the meds. If you never try you won't find one that works and I know you don't want to keep suffering like this.

I wish I had done it sooner because Prozac was not working well for several years. Oddly enough Welbutrin is decently tolerated by me and is keeping me out of the gaping jaws of the abyss. Low side effects and decent benefit. I'm a 5 out of 10 instead of a 1. I stayed at 150 because I like you experience the insomnia and heart rate issue. For now I am willing to keep using it because the alternative is awful. Doctor suggests I go to SR at 100mg.

Lexapro is a good drug. A lot of people have great success with it. I could not get on it. It just knocked me out.

As for withdrawal, I think you're experiencing depression not withdrawal. I could be wrong. Try the lexapro. If you think about it, what have you really got to lose? You deserve to feel better.

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  • 2 months later...

I have a question I hope someone on here can help with. I have been taking bupropion sr for a little over 8 weeks now. I am taking it for depression along with 40 mg celexa 45 mg remeron and 45 mg buspar . I started at 150mg and after a few days went up to 300 mg. Unfortunately the bupropion didn't do anything for me. Like others on here I experienced fatigue, nausea, ringing ears with no real positives. No honeymoon, no boost in energy and no increase in libido. After talking with my pcdoc, we decided we have given this long enough and I am going to stop taking it. My quextion, I went from 150 mg x 2 a day to 150 mg once a day and am 5 days into this decrease. I have been experiencing some nausea and this morning I had a hard time waking up and feel that the depression is increased . Does this sound like wellbutrin withdrawal symptoms and has anyone else experienced this with a dosage decrease?

.

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I have to say, after reading all your comments, that I must be incredibly fortunate. I've been taking 150 mg. bupropion for about 5 years, and have had not had any bad side-effects. It did exactly what my psychologist and GP said it would: it put a "floor" under my emotions. That's it! Not an instant happy pill by any means, but it certainly was effective at helping me to overcome my depression, stay sober, and get back to work. For the past several months I have been considering whether to withdraw from the medication. I had a converstation last year with my GP about it, and he did not seem to be against it. Why would I want to do this if I've been having such good results? Like some of you, I'd like to see how I can do without it. It has an obvious $ cost I could live without, and I'm just generally opposed to taking drugs if I no longer need them. When I presented this to my GP he said the only way to be sure was to stop taking them, and to let him know if I wanted to pursue it. I will likely see him again next month, and I think I'm going to go ahead and try withdrawing. He did not seem inclined to have me go "cold turkey", so I anticipate a gradual withdrawal over several weeks. It's easy to let the imagination run wild, mine certainly did when considering whether to try bupropion, but its effects were subtle, and I've had virtually no side effects other than slight, occasional tinnitis. I never even associated that with the med, since it often develops on its own with advancing age (I'm 60). I'll continue to read of your experiences with interest, and I'll let you know how it goes!

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Same here - 1 week on Wellbutrin and major ringing/tinnitus in my ears for months now. Pdoc says it is "very rare" - but I have seen/heard lots of similar stories...sucks.

I dont think I would ever touch an anti depressent again in my life I got the ringing (tinnitus) from 1 week on citalopram and i got off right away and its been 3 months and i still hear it

and people say it can take even longer or never go away

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  • 4 months later...

Dear Friends,

 

  I have been on Wellbutrin for about 2.5 months. I got super anxious and tense in my muscles with numbness in my limbs. I couldn't handle it anymore so I tapered off really fast from 300 mg to 150 in a few days and then down to non at all. Would I feel withdrawal effects even if only after 2 months? I feel spacey with a headache.

 

Thanks to anyone, I'm very scared and feel really lost and alone. 

 

O

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  • 1 year later...

Honestly Wellbutrin worked super, super well for the first time I was on it. I only needed it, which was kind of unheard of for me a year back.

Since then, though, after being put on it a couple times, it's failed. I think it might have to do with how it affects the nicotine receptor. For some, though, it's great...as it was to me, for well over a year.

As I remember, I slept a lot when getting off of it. But I also felt like more of a filled-out person, too, if that makes any sense.

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  • 6 months later...

Hi! I took Wellbutrin for only a 12 days. On the 12th day I started to have a terrible "bloated" feeling. I stopped taking the Wellbutrin immediately. It only got worse, however, and nothing seemed to help. I took gas pills, laxatives, anything and it still came back. It even felt like the pressure had built up so high that it was pressing on my bladder and making me pee every two seconds. It's been about 3 days and the bloating and constipation has not gone away. It's horrible! Has anyone else experienced this? Should I call my doctor? It's really freaking me out, but it was the only thing that I had changed about my medications in the last month. There's no other logical reason for this crazy bloating and constipation. Help!

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  • 2 weeks later...
On 9/8/2012 at 3:56 PM, Down That Road said:

I have been on and off a number of medications over the years. The only one that I ever had a problem with was Effexor, which was the worst I've ever felt in my life. I've gone off Wellbutrin before, cold turkey, and didn't have any real side effects that I recall. I'm not sure why. Perhaps because I was taking a serotonin medication at the time as well. I'm currently taking Wellbutrin again, this time with no other medication and am tapering off. I take SR 150 mg once daily and for the past two days have taken 1/2 a pill.

I am extremely tired already, fatigued as well as really sleepy. I've felt this before when I would forget to take the pill on a given morning, so I'm not really surprised. I'm feeling a little foggy too. More alarming to me is that when I am falling asleep or waking up I am feeling this kind of extreme impending doom, something awful is about to happen, panicky feeling. Today I've been trying to nap because I'm so sleepy, and I will sleep for a few minutes and then wake up, over and over and each time having this feeling. I also am having more vivid, intense dreams, including a lucid dream, none of which have been pleasant. The bad feelings abate somewhat once I'm up, but it really scares me. I also have my period, so I'm hoping that these effects are exacerbated by that and that this will not continue.

Has anyone else had something similar happen? I feel like I can handle the physical side effects but these emotional changes are very worrisome for me. I saw my doctor today and told her I wanted to taper off Wellbutrin to see what would happen because I felt it was making me too jumpy and my depression/anxiety symptoms were gone. She prescribed me 100 mg SR and told me to take it for a week before I stopped taking it completely, which doesn't seem that different from the 75 mg I've taken for the past couple of days, unless there is is some effect of breaking the SR in half or something.

Hi I know this post was from years a go but how did you end up feeling ?? I feel like in experiencing a lot of those symptoms now. Im taking wellbutrin XL 150 mg for almost 2 months and ive been having trouble sleeping and having bad episodes of depression on and off. And i wake up feeling like you described just with this horrible doomed feelings. My doctor said its just my bad depression and actually just uped the dosage to 300mg but i havent tried it

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On 3/17/2017 at 3:42 AM, Starfire_x1 said:

Hi! I took Wellbutrin for only a 12 days. On the 12th day I started to have a terrible "bloated" feeling. I stopped taking the Wellbutrin immediately. It only got worse, however, and nothing seemed to help. I took gas pills, laxatives, anything and it still came back. It even felt like the pressure had built up so high that it was pressing on my bladder and making me pee every two seconds. It's been about 3 days and the bloating and constipation has not gone away. It's horrible! Has anyone else experienced this? Should I call my doctor? It's really freaking me out, but it was the only thing that I had changed about my medications in the last month. There's no other logical reason for this crazy bloating and constipation. Help!

For sure call your doctor!

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On 3/18/2015 at 10:32 AM, Wheelman81 said:

I have to say, after reading all your comments, that I must be incredibly fortunate. I've been taking 150 mg. bupropion for about 5 years, and have had not had any bad side-effects. It did exactly what my psychologist and GP said it would: it put a "floor" under my emotions. That's it! Not an instant happy pill by any means, but it certainly was effective at helping me to overcome my depression, stay sober, and get back to work. For the past several months I have been considering whether to withdraw from the medication. I had a converstation last year with my GP about it, and he did not seem to be against it. Why would I want to do this if I've been having such good results? Like some of you, I'd like to see how I can do without it. It has an obvious $ cost I could live without, and I'm just generally opposed to taking drugs if I no longer need them. When I presented this to my GP he said the only way to be sure was to stop taking them, and to let him know if I wanted to pursue it. I will likely see him again next month, and I think I'm going to go ahead and try withdrawing. He did not seem inclined to have me go "cold turkey", so I anticipate a gradual withdrawal over several weeks. It's easy to let the imagination run wild, mine certainly did when considering whether to try bupropion, but its effects were subtle, and I've had virtually no side effects other than slight, occasional tinnitis. I never even associated that with the med, since it often develops on its own with advancing age (I'm 60). I'll continue to read of your experiences with interest, and I'll let you know how it goes!

Hey hope you're doing well now! How did it go with quitting the pill ?

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  • 9 months later...

Well, I am getting off of Wellbutrin because of the increased anxiety & negative thinking whenever I miss a dose or towards the end of its duration (I've been on the 24 hour 150mg version for about a month, which was a weaning off period; prior to that was on the 24 hour 300mg version for about a year and the 12 hour 200mg version twice a day for more than a year before that.) This is my first day after not taking it before I went to sleep last night. I've been fine for most of the morning, if a little spacy (which I put down to not sleeping well), but early this afternoon ... I just crashed. A few little negative bits of news, and I'm crying and feeling utterly useless. I've told my family to be prepared for me to be extra irritable this week, but I don't think I fully prepared myself for how I'd be feeling today. No physical symptoms so far, thank God, but my emotions are in the pits.

[Image of Charlie Brown saying 'I'm sick of myself.']

Yeah that about covers it.

 

Edited by 20YearsandCounting
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My bf is withdrawing from Wellbutrin and has been off it for about a month and he has been experiencing a number of side effects to include severe pain, muscle atrophy, terror nightmares, depression anger and mania and more. The mania in particular is the most troubling of them all as he has become a different person now, argumentative, controlling, paranoid, troubling thoughts and aggressive behavior and it's been a scary few months and it's gotten worse in the past few weeks even though he's completely off the drug now.  He has exhibited these traits before when he had a concussion a few years back and we've come full circle again. The only thing that helps sometimes is sleep and sex for the serotonin.  Does anyone know what to do to help treat his condition and restore his serotonin levels without taking more meds.  Please help.  

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  • 3 weeks later...

Hello,  I am new here, but am so glad I found this forum.  I am not new to Wellbutrin, however.  I have taken the name brand over 16 years.  I tried the generic when the cost got ridculous to no avail.  Last year I ended up in the ER with a severe anxiety attack when switched to generic.  But that is another post for another time. 😉

I have been off Wellbutrin now for almost 6 weeks.  I tapered for four weeks under the supervision of my doctor.  I felt it was time to see if I could quit(while I still had some to fall back on).  My doctor and I discussed some other medication because we both felt it was not doing its job anymore.  I have went from 300mg to 450mg and finally at 150mg SR over that 16 year time period. I have brief moments of anxiety, but was having them while on the medication anyway.  So all in all mentally I am okay.  I do feel I am still adjusting.

I have had "muscle twitches" and "charlie horses" for at least the last four years.  I do believe it was a side effect to the Wellbutrin.  When I was on my last couple of pills of tapering, the joint pain and two mentioned conditions increased tremendously.  In fact, I did not even take the very last taper for that reason.

I have had blood work and all was normal.  I am now waiting on further testing results for the possiblity of any other deficiencies.  These will be revealed to me April 30.  

I just have to ask if anyone else experineced any of these symptoms during usage or during withdrawal?

How long did withdrawal last?  I know that the longer one is Wellbutrin the longer the withdrawal may be and that it is stored in our fatty tissue.  Which I have done the Keto Diet, under Doctor's supervision as well.  I know my body is yelling at me right now....and adjusting. 

The new doctor I am going to is an Age Management Specialist/Nutrionist and I know he will help me.  I am 58 and always been in great health and able to walk, hike, bike, etc.  

I know that there are several possiblities to the cause of this..and it might not have anything to do with the Wellbutrin at all, but thought I would ask? April 30 seems so far away!  I sleep on my back and am doing all I know to do to avoid the muscle spasms.  I can deal with the twitches if I have to...but waking up to the spasm is awful!  

Praying it is all temporary....

Thank you so much!

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