Troydg 22 Posted August 7, 2020 My first topic - so I'll dive right in! I started on Bupropion about 6 weeks ago; I'm at 300 mg extended release daily. I also take 25mg of Trazodone at night. (Started both at the same time.) My issue is that about three weeks in, I started experiencing persistent constipation. I've upped my water, more walking, and start every day with a prune juice "cocktail". My question is - have any of you experienced the same issue? Anything that you did to alleviate it? Thanks in advance. 0 Share this post Link to post Share on other sites
austbobbie 4 Posted November 21, 2020 I know this is a late posting yet since I just began Wellbutrin recently, thought I would let you know, YES. I am having constipation. This happened to me when I began Effexor and the constipation eventually subsided. To help with the Wellbutrin constipation I am taking Senekotn drinking lots of water and eating lots of fiber. I am finally feeling less depressed from the Wellbutrin. 0 Share this post Link to post Share on other sites
