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Does Welbutrin have an antiinflammatory effect? What does it do specifically?


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I'm not sure about if Wellbutrin has any anti-inflammatory effect.  I'm going to look into that more, as I have rheumatoid arthritis and have noticed that my finger joints and knees are not quite as swollen.  

the doctor prescribed it when I was quitting smoking to help reduce the craving.  it is also used in conjunction with anti-depressants, like Prozac. 

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I've been on Wellbutrin for about 25 years and never heard about anti-inflammatory properties.  Just did a search and these two articles are interesting:

"Analgesic and anti-inflammatory activities of bupropion in animal models" - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4314873/

"Remission of Crohn's disease on bupropion" - https://www.gastrojournal.org/article/S0016-5085(01)70021-2/fulltext

I have Hashimotos Hypothyroid which is an autoimmune illness and am still battling high antibodies.  No idea if they'd be worse off Wellbutrin.  Interesting topic.

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