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Alternatives to ssri's?

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Hi there,

I've tried three ssri's (zoloft, prozac, and lexapro). Prozac gave me the most motivation and zoloft lowered my anxiety, but I just couldn't tolerate the side effects.

I'm wondering if anyone out there has had good success with something else outside the ssri's for major depression?

Thanks

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If you want to try natural methods first before seeing a doctor you could try,  (adaptogen herb) rhodiolla rosea, (herbal) st-johns wort, kanna seletium tortuosa (kanna), nootropic antidepressant by servier tianeptine all these are suggestions Ive heard people have had positive results with. 

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I had mild to moderate depression, and the OTC supplement SAMe (S-adenosylmethionine) has worked very well, with no side effects.  I take a comparatively low dose, 100 mg once a day, compared to what is commonly recommend by the manufacturers.  

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I just recently started taking  750mg of GABA once a day. I have been on 20mg and most recently 10mg of Lexapro for 2 years as 150mg of Wellbutrin. Unfortunately, my insurance ran out and my medicine was WAY too expensive to keep buying so I started doing my research and found out that GABA deficiency is very similar to serotonin deficiency. When I ran out of my medication, I decided to supplement the GABA instead. Now disclaimer, you should NEVER just stop taking SSRI's EVER, it will screw you up big time, but I didn't have much of a choice here so I thought, what the hell, might as well try something rather than nothing. So far it's been almost 2 weeks and I feel the exact same as when I was on SSRI's. My obsessive thoughts are gone, no anxiety, it's like I'm on my regular meds. Normally after about 3 days off of my meds, my mind starts racing, I get brain zaps, and I just feel terrible but so far 2 WHOLE WEEKS in and I feel normal. I may just fall in love with this stuff.

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On 5/1/2017 at 11:05 AM, kaymichele01 said:

I just recently started taking  750mg of GABA once a day. I have been on 20mg and most recently 10mg of Lexapro for 2 years as 150mg of Wellbutrin. Unfortunately, my insurance ran out and my medicine was WAY too expensive to keep buying so I started doing my research and found out that GABA deficiency is very similar to serotonin deficiency. When I ran out of my medication, I decided to supplement the GABA instead. Now disclaimer, you should NEVER just stop taking SSRI's EVER, it will screw you up big time, but I didn't have much of a choice here so I thought, what the hell, might as well try something rather than nothing. So far it's been almost 2 weeks and I feel the exact same as when I was on SSRI's. My obsessive thoughts are gone, no anxiety, it's like I'm on my regular meds. Normally after about 3 days off of my meds, my mind starts racing, I get brain zaps, and I just feel terrible but so far 2 WHOLE WEEKS in and I feel normal. I may just fall in love with this stuff.

And what if you start taking an SSRI at the doctor's recommended dose, but with no buildup time?

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