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Whole days of sluggish/tired

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I switched from Zoloft to Cymbalta earlier this year. I am recently up to 90 mg Cymbalta but had been at 60 and 30 before.


Frequently, maybe once a week or every other week, I have a whole day where i'm totally wiped out and sluggish, even if I slept well, haven't done anything very tiring.  I end up just sleeping all day.  Though sometimes my iron gets a bit low, there's nothing in my bloodwork to suggest that these days are caused by physical conditions.


Does anyone else get this with Cymbalta?

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Cymbalta has always had the opposite effect on me, making me more stimulated and wakeful, so I've never personally experienced this.  However, I do know others who have said it makes them extremely sleepy, although it was usually in the start-up weeks.  Since you recently increased the dosage, I don't think it's unreasonable that you might see this as a side effect, but it seems strange that it would hit you for just one day (seemingly randomly).  Maybe monitor how frequently this is happening and see if there is a pattern. For example, does it happen after a few days of high energy and maybe not sleeping so well? It certainly might help to let your Dr. know.  



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I've been on Cymbalta for about 2 months. I was up to 90mg a day, and am now tapering down to get off this drug. I have severe depression, and it definitely makes me feel extremely unmotivated, and not wanting to do anything. Now that I'm tapering down, I'm feeling a bit better. I'm on Lexapro, 20mg and Adderall for ADD. Maybe I'll try something else to replace the Cymbalta, maybe not. I'll see how I feel. 

I hope you feel better and it starts to help you!! 

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