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Medication For Anhedonia

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Secondary question:

has anyone successfully added a serotonin 5ht2c antagonist (which leads to dopamine inhibition) like nortriptaline or miterazapine to reverse SSRI anhedonia/apathy? Seen mixed success online.

also, I refuse to add low dose anti-psychotics like olanazipime to block those receptors.

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On 10/12/2016 at 9:03 AM, jaiho said:

I found SSRI + Nortriptyline to be quite a good combo

all nortriptyline ended up doing for me was sexual anhedonia, granted i was only on bupropion along side it.

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7 hours ago, CF900 said:

all nortriptyline ended up doing for me was sexual anhedonia, granted i was only on bupropion along side it.

I found the SSRI to be a critical part of the combo, there's something interesting about the synergy of the two.

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4 hours ago, jaiho said:

I found the SSRI to be a critical part of the combo, there's something interesting about the synergy of the two.

what ssri and what dosages are you doing? pdoc is wanting me to try trintellix.

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The process of recovery from anhedonia is primarily austerities.
It was nice to take a tablet of happiness and quickly and painlessly return to the world of the living. UNFORTUNATELY EASY SOLUTIONS OUT OF anhedonia NO!

It should be avoided until a satisfactory well-being:


Alcohol-alcohol destabilizes the opioid system in the brain.
Nicotine Nicotine -nadużywanie destabilizes the flow of acetylcholine and dopamine in the brain.
Pornography, compulsive ************* / sexual addiction extremely harmful compulsion, reduces the levels of dopamine and endorphins in the reward system in the brain also leads to dysfunction cycle of serotonin in the hippocampus. konsekwencje- deep depression with anhedonia, neurotic states running with a very strong anxiety, fear, insomnia, high risk of suicide. If left untreated, often leads to impotence.
Kawa in excess causes severe anxiety reaction rebound is impaired concentration, headaches, sleep disorders.

The drugs I will not even mention - they are determined by one słowem- death!



When we will feel as we expected we do not need to return to bad habits.
Well, unless you want to experience again hell of anhedonia.

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back on these forums since a long time... i think of all the meds ive tried fluoxetine is the one that made me feel the most "real". in the sense of being there, immersed, enjoying going to the cinema or stupid stuff like that which i had never understood before. probably stimulated arousal. i ahve been trying a lot of other stuff and stimulants (reboxetine, bupoprion, moclobemide, tianeptine, modafinil, methylphenidate), and while they all did their thing, none of them (maybe with the exception of high dose, constant moclobemide at his peak) has given me anything similar.

 

now the problem is fluoxetine is a plague on the genitals. i still suffer (7years later) from genital anaesthesia.

 

tlddr: what is a good adjunction to fluoxetine to counter the sexual side effects?

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I strongly suggest anyone suffering Anhedonia get tested for Lyme, as well as CIRS (mold exposure).. Anhedonia is a result of  HP axis dysregulation caused by inflammatory cytokines. Adding psych meds is just perpetuating the disaster!  Everyone always wants the "magic pill" solution. Sorry to tell you it doesn't exist! 

Edited by jarmenti

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Hi all! I will have to take the time to read through the various posts when I have time (currently busy with college courses). I remember when the Anhedonia forum was first created so glad to see it still going. I had severe anhedonia from around 2012 through 2016. I remember I told my psych that I felt like it I had reached an end, as far as getting any worse around the end of 2016. Then, from 2017-2019 is has slowly been fading. Unless you have a really good psychiatrist (like I presently have) I think it's something that is not easily fixed with medicine. There are 3 meds have shown to help me, from least to greatest of help: Abilify, Modafinil and stimulants. The issue with stimulants is that most doctors will not prescribe them unless you've been suffering from it for many years and then they still might not. They've help me better than anything else. Note, I found at low doses to be effective, only if it's a light stimulant effect. At higher doses and stronger stimulant effect, it seems to make matters worse, so the dosage is sort of an art, you have to play with it......That and time is the only thing that has seems **** the anhedonia. It's a horrible symptom of depression, that you all are suffering from so I definitely hope you all get some relief soon. At this point, my interest level has slowly started coming back.  I spend sometime hours in my studies where that would have been impossible just a year or so ago. One thing though, and it's just my opinion but I think I'm right about this. The anhedonia will not won't last forever. It might be almost a decade lost like in my case  (or god forbid longer), but it will eventually start to fade and go away. It just takes a long time for many. But again, those 3 meds all helped me so if you take meds, definitely give them all a try and play with the dosage as much possible before moving on. Hopefully this info helps somebody!

Edited by james555

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