Jump to content

Answers To Curing Anhedonia/numbness/apathy, No. 2


Lioninwinter

Recommended Posts

We need to get some medical experts in here. Brief them on the condition, on people's responses to the condition, on the general lack of understanding when it comes to this condition. I'm just thinking that we need some people with expert knowledge of the human body. Plus, should we manage to have any breakthroughs on various treatments, those experts can then contact the people they know and start getting some studies done on those breakthroughs and treatments.

 

I'm thinking people from the National Center for biotechnology information. http://www.ncbi.nlm.nih.gov/

Sounds like a great idea! Slightly off topic but I've been in contact with Neuralstem but no response as of yet. :(

Link to comment
Share on other sites

  • 3 weeks later...

Hi everyone!
I am suffering from anhedonia, too... followed by a very intensive stress period, started by a personal crisis in the end of this August. Couldn't sleep for days, and my "batteries" were totally exhausted.
I've been through some s***ty days, my energy levels are quite okay... however, my anhedonia not going to be healed anytime soon.

I found a little bit of information, which might give you hope:

http://www.crazymeds.us/CrazyTalk/index.php/topic/26730-my-mirapex-experience-pramipexole/page-2

"For any rational person listening, irreversible inhibition does not mean that your receptors will be inhibited for life even after you go off the med.  You know why?  Because your cells make more.  They have this nifty stuff called DNA and mRNA and ribosomes to make new , including receptors.  Once you go off a med, the recycling may take a while, but things go back to normal (tardive dyskinesia might be an exception, but you don't get that from only drugs which are irreversible inhibitors).  There are a ton of drugs out there which act by irreversibly inhibiting something.  Aspirin is one.  Most MAOIs are too.  Also, 5-HT7 receptors aren't the ones usually talked about when it comes to antipsychotic or other psychiatric drugs.  Those are D2 (and D3+D4) and 5-HT2 and 5-HT1A."

Sounds a bit positive. :)

Link to comment
Share on other sites

  • 2 weeks later...

Hi everyone.

My name is Tianna and I've had many mental illnesses, but 2 years ago is when it got so bad , keep in mind I'm only 17.. But I'm on 5-6 different medications. I realized after taking Zoloft for I believe a week or 2 I noticed I couldn't feel anything. I found music was the first to go , I never knew what Anhedonia was so I explained to my doctor guy that I couldn't feel anything and he upped my dose to 200 mg. which made it all worse but I got so used to it I felt like it was just depression until I noticed my feelings for everything I once loved has just faded and disappeared. Now I explained that to him and he gave me 18mg of concerta and I've been having panic attacks more than I usually would. I honestly have no joy for anything anymore , but sleep. When I wanna think about love I have to go as deep as the person or pet in danger. For example I look at my pug and just think what are you , and just not pay attention although I know I will not harm her , but my mind has to go so far that I have to hold her and vision someone trying to **** her , which really spooked me of how much I've lost the ability to care for people and my dream has always been to be a counsellor. I would love love to have my normal human feelings without having to take pills. /:

Link to comment
Share on other sites

Poland... This is unbelievable... I can't explain them anything cause the illness took my ability to think fast and clear. I forgot so many important facts... I feel like a ******. I barely think and speak, it's like I'm in the cage which is protecting me from explaining CLEARLY what's happening to me.  One doc said something like this: "Sir, you're not ill. Get some work, u want to spent rest of ur life in bed? - It's your choice! (I don't give a ###") I'm going to get SPECT scan and if it's something wrong, then it will be proof that it's not psychological. Fckng ignorants... 

This doc which I mention is really arogant. One day, the patient told that he is afraid of meds cuz he doesn't know what they can do to him. Doc literally said: "Who knows more about meds, YOU OR ME?!?!?! HURR DURR", "If u r rly afraid then get out and get some homeopathy!". I hope this post is understandable... 

Edited by neur0nz
Link to comment
Share on other sites

I had anhedonia for a while, so bad I never felt sexually attracted, coyldny even watch a porno and feel anything. No emotions.

I went to an endocrinologist, found out I had abnormal hormone levels. Prolactin high, Free t3 was abnormaly low. Which is odd since im 27. This all started after crazy stress, while I was on an anti depressant.

They got me on armour thyroid and.it completely Demolished the anhedonia. I feel like I did when I was 16. My free t3 levels went up, tsh went down, my free testosterone is normal now.

It's been three months, it wirks every day. I noticed before I went to see a doc, which im sure most of you notice also, is that I never had energy, but still I couldnt sleep. Melatonin helped. Licorice root helped somewhat.

Also, my temperature was abnormaly low. Which told me.I had slower metabolism, which was correct. My feet were cold, my hands, I had fat developing around abdomen, and I always had super low body fat. I never felt excited, happy, content, tired, sad, mad, anything.

The thyroid med simply cured the anhedonia. Theres no question that I had what you peoplr refer to as anhedonia. It's completely gone.

Libido is normal, Maybe too normal. Im anxious again tho, but I meditate

Hope someone benefits from this.

Link to comment
Share on other sites

I had anhedonia for a while, so bad I never felt sexually attracted, coyldny even watch a porno and feel anything. No emotions.

I went to an endocrinologist, found out I had abnormal hormone levels. Prolactin high, Free t3 was abnormaly low. Which is odd since im 27. This all started after crazy stress, while I was on an anti depressant.

They got me on armour thyroid and.it completely Demolished the anhedonia. I feel like I did when I was 16. My free t3 levels went up, tsh went down, my free testosterone is normal now.

It's been three months, it wirks every day. I noticed before I went to see a doc, which im sure most of you notice also, is that I never had energy, but still I couldnt sleep. Melatonin helped. Licorice root helped somewhat.

Also, my temperature was abnormaly low. Which told me.I had slower metabolism, which was correct. My feet were cold, my hands, I had fat developing around abdomen, and I always had super low body fat. I never felt excited, happy, content, tired, sad, mad, anything.

The thyroid med simply cured the anhedonia. Theres no question that I had what you peoplr refer to as anhedonia. It's completely gone.

Libido is normal, Maybe too normal. Im anxious again tho, but I meditate

Hope someone benefits from this.

Good for you. My hormone levels are completely normal, however I think the cause of the anhedonia is my ****ed up pleasure centers due to continous stress.

 

My meds now are: Frontin (same as Xanax), because having continous anxiety which severely interferes with my sleep, and Coaxil (an SSRE with Tianeptine).

 

I am going to the gym regularly, eating vitamins, and go sometimes running with sprinting.

Edited by silverlining_92
Link to comment
Share on other sites

I was struggling with anhedonia for a couple years. I tried everything. Things that helped were exercise, proper sleep, diet, and trying to set goals. Also, I take supplements and vitamins because I am deficient. I noticed a change after try several things, but not all at once, so I believe it has been a combination of things over the past few months that have slowly helped me get to where I aM now.

I got tested for deficiencies. I am low in iron. So I take iron supplements. I have extremely low testosterone for my age, so I am on testosterone replacement therapy, I also got diagnosed with adult adhd and depression. I've been on vyvanse and brintellix for over a month. All of these things slowly started to make me feel better. I went from wanting to disappear and give up my life to reorganizing my life and now I have a new job, completed training, certified first aid and several other courses, got a raise, New friends, and I feel engaged in life now. I actually want to do things again, I feel hope again, I have an internal drive again, and the fatigue and no motivation have lessened greatly. Now, this is just my story, everyone deals with apathy and anhedonia differently, but I hope this may help someone. Also, there were bumps and downs throughout this process, but getting through them was definitely worth it. I do worry about being on this stuff long term, but from being apathetic and anhedonic for years, and now being able to function and feel human, it's worth it for me for now. Hopefully this continues, I've had about just over a month of feeling good like this, so fingers crossed.

Hope this helps, sorry for wall of text, I'm on phone and in a hurry lol.

Link to comment
Share on other sites

Poland... This is unbelievable... I can't explain them anything cause the illness took my ability to think fast and clear. I forgot so many important facts... I feel like a ******. I barely think and speak, it's like I'm in the cage which is protecting me from explaining CLEARLY what's happening to me.  One doc said something like this: "Sir, you're not ill. Get some work, u want to spent rest of ur life in bed? - It's your choice! (I don't give a ###") I'm going to get SPECT scan and if it's something wrong, then it will be proof that it's not psychological. Fckng ignorants... 

This doc which I mention is really arogant. One day, the patient told that he is afraid of meds cuz he doesn't know what they can do to him. Doc literally said: "Who knows more about meds, YOU OR ME?!?!?! HURR DURR", "If u r rly afraid then get out and get some homeopathy!". I hope this post is understandable... 

It is sad to hear that. Tell us how your SPECT went.

Link to comment
Share on other sites

  • 2 weeks later...
  • 4 weeks later...
  • 1 month later...

I have suffered from Anhedonia my entire life. I am 52. I have been married twice. My ex-wife slept with other men because I had no sexual interests of any kind, and my current wife has followed suit for the same reason. I have been told we are a cuckold couple, meaning that while I remain faithful, my wife has sex with other men, with my permission.

 

I have no idea what it would feel like to be jealous, nor do I feel unloved by my wife, although she has sex with other men. She enjoys sex. I don't. So, why not let her do what comes "natural?"

 

Through out my life I dated several women, and even liked fondling them, but I never thought to actually have sex with them. I had/have no sexual desire. And I would find out that although we were dating, the women I dated slept with other men, often because I got them hot and bothered. I never realized that fondling a woman made her feel sexual, or want sex. And I still don't get it, mentally or physically.

 

I can't remember ever feeling anything. Everyone thinks I am the coolest guy they've ever met, because nothing ever seems to bother me. They've mistaken my apathy for coolness. Someone once told me that I have lay back down cold. Not only do I suffer from anhedonia, I also have what is medically considered a micro-penis. And I guess it's only right since it serves no real purpose other than urination.

 

My wife is 5'2" tall, has C cup breasts and weighs 105 pounds, She is very attractive, yet I have no desire to have sex with her. When we have had intercourse i found it to be quite boring. I don't even ejaculate. And she has never orgasmed with me.

 

I actually like watching my wife have sex with other men because I like seeing the joy in her face, and how much the other men seem to enjoy her. An hour before our wedding, I arranged for a friend of my wife to have intercourse with her an hour before she walked down the isle. And we had 15 other men assist in consummating our marriage on our honeymoon. My wife says that our honeymoon was the best part of our marriage.

 

I always thank the men that have sex with my wife, because they are doing something for me. They are better equipped, and they actually like having my wife. And they make my wife feel attractive and wanted, something I don't do.

 

My wife always says that she wishes I was more like other men, but she knows that can never happen. I know this as well. I raised three children with my ex-wife that were fathered by other men. My parents knew that the children weren't mine biologically, but they were happy to have grandchildren.

 

Even as a child, nothing ever excited me. My parents always wondered why I was never happy at Christmas time, but they never did anything about it. Our neighbor's husband slept with every girl I dated in high school. He was a biker. He was very masculine and forward. And it didn't bother me. My first wife got pregnant by him with our first child.

 

At school I was bullied daily and made fun of because of my micro-penis. And I was called a fag. I eventually began to believe what they said about me, and began living that way. I learned what men are like, and how different I was from them. I have always been submissive to other men, and women for that matter. If I had to fight, I wouldn't know how to defend myself. And I have been beaten up more times than I can remember.

 

The men that have sex with my wife tell me how lucky I am to be married to such a sexy woman that loves sex as much as she does. I don't feel lucky, but I am "happy" that they make my wife feel wanted and desired. My wife tells me that I don't often show my love for her, and I tell her that I do so by letting her have other men. And because I do not feel emotions, it is a choice I've made to love her.

 

I see other men having sex with my wife as a relief. As long as my wife is having sex with other men, I don't have to pretend that I want or enjoy sex. I do often wonder what it must feel like to desire something or someone. And I wonder what it must feel like to want something and actually get it. I don't want or need anything, and I rarely even eat. The men that have sex with my wife, and my wife as well, seem to really enjoy sex, a lot and often. I wonder what it must be like to enjoy sex.

 

I have an exceptionally high pain tolerance, too. I don't drink or do any drugs, but I do smoke tobacco. I do enjoy smoking, though, a lot. It is the one thing that I do derive pleasure from. I think I enjoy smoking cigarettes as much as other men seem to enjoy having sex with my wife.

 

My wife's favorite lover is a man that is 20 years her senior. She has known him for about 25 years now. He is the one that made love to her before our wedding. He is married, too, but his wife doesn't like sex, either. My wife likes that he actually makes love to her and doesn't just have sex with her. My wife considers him her other husband.

 

My wife's favorite lover and I have the same first name. So, when my wife talks about making love to him, and how he makes her feel, people think she is talking about me. And people think I am an amazing man. Other wives wish they had a husband like me. Little do they know.

 

Not only is my wife's lover a good lover, his penis (soft) is like three times the size mine is (hard.) And my wife says that he is the perfect size for her. My wife's lover's wife knows that her husband and my wife are lovers. And she, like me, likes that she doesn't have to have sex with her husband. And she likes knowing that my wife does for her husband what she would rather not do.

 

I am not totally apathetic, thankfully. My passion is my vintage clothing and my vintage shoe and hat collections. I like to play dress up at work. And people tell me I look sharp or dapper. I can say that I like that. It doesn't make me feel anything, but it is nice to be noticed. The thing is that when my wife says I look good, I believe she is saying it just because I am her husband.

 

I have never had a real friend. The only "friends" I have now are men who have sex with my wife on a regular basis. Her favorite lover is a plumber,  another is a mechanic, another is an architect,  another is in IT and his son is a welder. These men have been good "friends", as well as lovers for my wife.

 

People think I have an outgoing personality, but in reality I am very much an introvert. I put on a face, pretty much. Every one says I am the happiest guy they know. In reality I am  always in a depressed mood. I have never really been good at anything. Anything I have ever done, I do it until I am kind of okay at it, then I quit.

 

My wife's IT lover's wife knows that her husband and her son have sex with my wife. Our son and their son knew each other and that is how we all met. The day we met them we invited them to share our hot tub with us. We don't wear clothes in the hot tub because threads and soap are not good for hot tubs. When my wife saw her IT lover and his 18 year old son naked, she knew she wanted to "know" them better.

 

Our son's friend's mom, the IT lover's wife, noticed my wife staring at her husband and her son's packages. When me, my wife and the IT lover's wife were alone, the IT lover's wife told us that she and her husband didn't have sex, because she had back problems, and her husband was too big and too rough. My wife told her that she likes them bigger and she likes it rough. The IT lover's wife told me and my wife that if my wife had sex with her husband, "Have at it. I'm not putting out."

 

The IT lover's son once told me, when he was with my wife and I was in the room, naked, that the only difference between me and a woman is that women have ****. My mother even told my current wife that she used to dress me as a girl when I was little because she had always wanted a little girl. And I had cross-dressed for the last three years of my first marriage.

 

Other men make my wife happy like I used to with older men when I was a teenager. If I could, I would have sex with men on a regular basis, but I am older now and neither men nor women are attracted to me anymore. I'm not attracted to men, but I knew that when I let them have sex with me it made them happy. Now the only way my wife is happy is when she is with other men.

 

All the things my ex and my current wife have wanted me to be, other men already were/are. So, to me it makes sense for them to be with my wife because they are already what my wives wished I was. My current wife calls me her domestic god because I am such a good house husband. She says I am not much of a man, but I am a good, loving husband.

 

My wife recently had me try on a pair of her panties. Once I had them on, she made mention that I didn't even make a bulge in her panties. and she was right. My current wife told my mother about this experience and my mother told my wife that I had wore panties most of my life because I liked how they felt and they fit better than boys underwear did.

 

My whole life I have thought numerous times of committing suicide, but I have never attempted it. What keeps me going day after day is knowing that other men are making my wife happy on a regular basis. Even though it is other men having sex with my wife and making her happy, I like to think it is because I allow her to have sex with them and because they have sex with my wife that I have value.

Link to comment
Share on other sites

Have you looked into DBS, Hatman?

I heard a case of a woman just like you. she had been exactly like you since she was a child. though a more extreme case, in no photo did she smile. No emotions. This is what severe depression/anhedonia does.

In her 50s, she got into a trial for DBS treatment. Her depression was instantly cured. Her emotions all came back. it was like she was born again. I think for us, DBS is the answer but it isn't widespread as yet. It's becoming that way for Parkison's disease.

here's the story

 

Link to comment
Share on other sites

  • 7 months later...
  • 5 months later...
On 04.03.2016 at 11:30 AM, jaiho said:

Have you looked into DBS, Hatman?

I heard a case of a woman just like you. she had been exactly like you since she was a child. though a more extreme case, in no photo did she smile. No emotions. This is what severe depression/anhedonia does.

In her 50s, she got into a trial for DBS treatment. Her depression was instantly cured. Her emotions all came back. it was like she was born again. I think for us, DBS is the answer but it isn't widespread as yet. It's becoming that way for Parkison's disease.

here's the story

 

Any news/ info on DBS for anhedonia/depression?

Link to comment
Share on other sites

Hi everyone,

I appreciate this thread as it  gives me hope. My anhedonia first came on 8 months ago after a psychotic break. At the hospital I was treated with Risperdal. Thus, I am not sure if my anhedonia is a result of me taking the antipsychotic or due to the psychotic break. Since then I have just felt void and empty. I use to have a passion and zest for life and wanted to live everyday to the fullest. Now, I have no motivation and have moved back home with my parents. Food still tastes good and as a result, I have put on 30-40 pounds to fill the void. I am not working. For me I believe it might be more psychological as it feels like my 'cognitive map' has disappeared. My values and beliefs have all disappeared and I feel as if I'm just existing day to day. Anybody else have similar experiences?

Link to comment
Share on other sites

6 hours ago, AMonsterCalls said:

Hi everyone,

I appreciate this thread as it  gives me hope. My anhedonia first came on 8 months ago after a psychotic break. At the hospital I was treated with Risperdal. Thus, I am not sure if my anhedonia is a result of me taking the antipsychotic or due to the psychotic break. Since then I have just felt void and empty. I use to have a passion and zest for life and wanted to live everyday to the fullest. Now, I have no motivation and have moved back home with my parents. Food still tastes good and as a result, I have put on 30-40 pounds to fill the void. I am not working. For me I believe it might be more psychological as it feels like my 'cognitive map' has disappeared. My values and beliefs have all disappeared and I feel as if I'm just existing day to day. Anybody else have similar experiences?

@AMonsterCalls My story is so much like yours! Back toward the end of August I had drug induced psychosis due to some bad garden shrub and I was put on Risperdal in the hospital. I too man not sure whether the risperdal or the psychotic episode gave me the anhedonia but I've had it ever since and it's gotten slightly worse over the months in terms of libido and enjoying music. I'm currently on Prozac which is doing nothing and have been on wellbutrin which did nothing as well. I'm also currently on abilify. I hope that for both our sakes this anhedonia isn't permanent.

Link to comment
Share on other sites

  • 3 weeks later...

I strongly suspect my anhedonia came upon because of stress/anxiety. I've tried many medications to no avail ( Zoloft, Wellbutrin, Effexor, Tegretol,). Ive spent a lot of time researching about different medications and neurotransmitters (specifically dopamine). After reading through a lot of the no 1 anhedonia thread here I'm thinking my best bet is to try and do things I used to enjoy and stop obsessing about meds and neurotransmitters. Right now I'm on 400mg of tegretol and I've been on vyvanse 30mg for 5 days. I manipulated my psych into giving me a stimulant because I wanted to try it for my depression (was given it for concentration). Now I realize vyvanse could just make the problem worse in the long term. 

 

So, tomorrow I might stop all the meds and just start taking omega 3 fish oil and St. John's wort. It will be a struggle for me just to force myself to do things I once enjoyed and not obsess and worry.

 

if anyone knows, am I right to be fearful of vyvanse? Will it hurt my dopamine in the long term?

Link to comment
Share on other sites

  • 2 months later...

SRI induced emotional blunting & broken reward system

Hello,

I'm suffering from depressions and social anxiety. Unfortunately it looks like I have very unpleasant side effects from SRIs: I can't feel anymore, my emotions are numbed. My motivation is non-existent and I am indifferent to everything. When I watch some emotional video I used to cry before, now I can't feel that emotion any more. I'm also not sure if I can fall in love any more. I had 1.5 year "sort of a relationship" and I really liked that girl, now I feel nothing for her. I also have that feeling like I can't really enjoy good moments anymore. I just never feel truly happy or sad. I can't laugh, I can't cry, it looks like I can't experience intense feelings. I also have problems to reach orgasm and I don't enjoy sex, ************* and erotic sensations like I used to.

And they have all caused me to lose my appetite almost completely + weight loss. My doctor said it's unlikely the SSRIs causing my weight & appetite loss. I am currently considered "underweight", I was a "healthy normal weight". I can go 24 hours without food and still won’t be hungry or have appetite…

Now I don't know what to do. I need some meds cause it seems like I'm not able to live without it but I also don't want to go back to emotional emptiness & Zombieland. I haven't tried any combination of medications yet. All of them separately. 

I tried:
Fluoxetine - this was actually quite good. Gave me some emotional blunting, but only modest. I had to discontinue it due to suicidal ideation.
Paroxetine - emotional blunting + horrible physical side effects.
Citalopram - emotional blunting + absence of motivation.
Sertraline - emotional blunting + absence of motivation.

I'm starting to be really desperate and my doctor told me she don't want to treat me any more due to I'm not good patient and I'm not trying. I found a new psychiatrist and I will have a first appointment in 2 weeks but I don't know what to suggest to her. I was thinking about Wellbutrin but what I read it doesn't help with anxiety and weight gain. Has anybody some experience with a similar situation? Which antidepressant would be suitable for me? I don't know which one and I have the feeling that I'm starting to go out of options.

If there is someone who had the same problem and found some solution: please write me :Coopwink:

Link to comment
Share on other sites

I've been doing some reading & research and there is the hypothesis that SSRI-induced-agonism of 5HT2C & 5HT2A receptors dampens the dopaminergic transmission in certain brain regions thus causing the specific SSRI side effects. Antagonism / Inverse Agonism of these receptors should theoretically "resolve" the problem. What medications do antagonize / inverse agonize these receptors? Well, according to my sources: Nortriptyline, Mirtazapine, Agomelatine, Trazodone, Nefazodone... so far. I've been also thinking about trying Buspirone.

Some people say that Sertraline has some dopaminergic action, but at 100mg I didn't feel it. Its dopamingergic action is obviously to weak to have any significant effect.

Are there any other reliable theories on what is causing this? And what could help?

 

Link to comment
Share on other sites

  • 3 weeks later...
On 11/15/2014 at 8:33 AM, nostromo said:

how many of you guys play a lot of videogames?

I started playing video games again when I got anhedonia but I don't enjoy them and playing them feels like a chore to me. the only game I can stand to keep playing is gta5 and even that is boring to me. I just do it so I don't lay in bed staring at the ceiling all day.

Link to comment
Share on other sites

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now

×
×
  • Create New...