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  1. Why is this medication prescribed? Prazosin® is used alone or in combination with other medications to treat high blood pressure. Prazosin is in a class of medications called alpha-blockers. It works by relaxing the blood vessels so that blood can flow more easily through the body. High blood pressure is a common condition and when not treated, can cause damage to the brain, heart, blood vessels, kidneys, and other parts of the body. Damage to these organs may cause heart disease, a heart attack, heart failure, stroke, kidney failure, loss of vision, and other problems. In addition to taking medication, making lifestyle changes will also help to control your blood pressure. These changes include eating a diet that is low in fat and salt, maintaining a healthy weight, exercising at least 30 minutes most days, not smoking, and using alcohol in moderation. How should this medicine be used? Prazosin comes as a capsule to take by mouth. It usually is taken two or three times a day at evenly spaced intervals. The first time taking prazosin, you should take it before you go to bed. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take prazosin exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Your doctor will probably start you on a low dose of prazosin and gradually increase your dose. Prazosin controls high blood pressure but does not cure it. Continue to take prazosin even if you feel well. Do not stop taking prazosin without talking to your doctor. Other uses for this medicine Prazosin is also used to treat benign prostatic hyperplasia (BPH, noncancerous enlargement of the prostate), congestive heart failure, pheochromocytoma (adrenal gland tumor), sleep problems associated with post-traumatic stress disorder (PTSD; an anxiety disorder in people who experience or witness a traumatic, life-threatening event), and Raynaud's disease (condition where the fingers and toes change skin color from white to blue to red when exposed to hot or cold temperatures). Talk to your doctor about the possible risks of using this medication for your condition. This medication may be prescribed for other uses; ask your doctor or pharmacist for more information. What special precautions should I follow? Before taking prazosin, tell your doctor and pharmacist if you are allergic to prazosin, alfuzosin (Uroxatral), doxazosin (Cardura), terazosin, any other medications, or any ingredients in prazosin capsules. Ask your pharmacist for a list of the ingredients. tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention: beta-blockers such as propranolol (Inderal, InnoPran, in Inderide); medications for erectile dysfunction (ED) such as sildenafil (Revatio, Viagra), tadalafil (Adcirca, Cialis), or vardenafil (Levitra, Staxyn); and other medications for high blood pressure. tell your doctor if you have narcolepsy (a sleep disorder that may cause extreme sleepiness, sudden uncontrollable urge to sleep during daily activities) or if you have or have ever had prostate cancer or liver disease. tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking prazosin, call your doctor. if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking prazosin. If you need to have eye surgery at any time during or after your treatment, be sure to tell your doctor that you are taking or have taken prazosin. you should know that this medication may make you drowsy or dizzy. Do not drive a car, operate machinery, or perform dangerous tasks for 24 hours after the first time you take prazosin or after your dose is increased. ask your doctor about the safe use of alcoholic beverages while you are taking prazosin. Alcohol can make the side effects from prazosin worse. you should know that prazosin may cause dizziness, lightheadedness, and fainting when you get up too quickly from a lying position. This is more common when you first start taking prazosin, when your dose is increased, or when another blood pressure medication is added to your treatment. To help avoid this problem, get out of bed slowly, resting your feet on the floor for a few minutes before standing up. If you experience these symptoms, sit or lie down. These symptoms may also occur if you drink alcohol, stand for long periods of time, exercise, or if the weather is hot. If these symptoms do not improve, call your doctor. What special dietary instructions should I follow? Follow your doctor's directions for your meals, including advice for a reduced salt (sodium) diet. What should I do if I forget a dose? Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one. Check with your doctor if you have missed two or more doses. What side effects can this medication cause? Prazosin may cause side effects. Tell your doctor if any of these symptoms or those listed in the SPECIAL PRECAUTIONS section are severe or do not go away: weakness tiredness headache nausea Some side effects can be serious. If you experience any of the following symptoms, call your doctor immediately: hives rash itching difficulty breathing fast, pounding, or irregular heartbeat chest pain painful erection of the chicken that lasts for hours What should I know about storage and disposal of this medication? Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication. In case of emergency/overdose In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911. Symptoms of overdose may include the following: drowsiness decreased reflexes dizziness lightheadedness fainting What other information should I know? Keep all appointments with your doctor and the laboratory. Your blood pressure should be checked regularly to determine your response to prazosin. Before having any laboratory test, tell your doctor and the laboratory personnel that you are taking prazosin. Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription. It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies. This branded product is no longer on the market. Generic alternatives are available. Last Revised - 03/15/2015 Source: http://www.nlm.nih.gov/medlineplus/druginfo/meds/a682245.html#other-uses
  2. 7 Antidepressant Side Effects That Are Weird But Completely Normal JR Thorpe If you’ve been thinking about going on antidepressants or adjusting your dosage, chances are you’ve heard about the holy trinity of possible antidepressant side affects: weight gain, fatigue and libido problems. These side effects are the most well-known because they’re the ones that cause the most complaints among sufferers. But there are other side affects of antidepressant medication that are common but rarely talked about — and they can seem utterly bizarre when you’re experiencing them. The science of side affects can be difficult to understand. But it seems, in large part, that the range and degree of antidepressant side affects you’ll experience is determined by your genetics. Scientists are now postulating that genetic testing may actually help users find the right antidepressant with the fewest side effects, but those days are still pretty far off — so for now, if you’re trying a new medication, the only way to find out what side effects will impact you is to keep a close watch on what you personally are experiencing. Though these 7 side effects are common and not harmful, the usual rules still apply: if side effects persist after the usual antidepressant adjustment period (normally several weeks) and are seriously problematic for you, you need to see your doctor and consider your options. I also have to point out that not every thing that happens to you can be blamed on your antidepressants; you probably didn’t get a wart from them, for instance. But that blurry vision you’re suddenly experiencing? Yeah, maybe you got that from your new meds. So don’t panic — you’re just undergoing perfectly normal side effects of antidepressants that nobody seems to talk about. 1. Brain Zaps If you’re lowering a dose or coming off antidepressants entirely, chances are you’ll experience brain zaps, which are like electrical shocks in your head; other names for the feeling include brain shocks or shivers. It feels as if somebody’s let off a tiny firework in your skull. It’s bizarre, but usually not particularly distressing, and not harmful. Not much is known about it, but it seems to be caused by your neural circuits adapting to their new chemical situation. 2. Night Sweats It’s estimated that between eight and 22 percent of antidepressant users experience the glory that is night sweats — and yet, nobody seems to talk about the phenomenon. Probably because it’s sticky and unpleasant. We’re not entirely sure why it happens, but one current theory is that antidepressants activate the thermoregulatory center of the brain, causing the body to over-regulate its own temperature — leaving you soaked in sweat. 3. Flatulence This is an interesting one: antidepressants can impact our bowels so intensely that we can’t possibly blame all that gas on the dog. Antidepressants have been associated with farts, bloating and digestion problems in general. But certain antidepressants are actually prescribed to people with Irritable Bowel Syndrome (IBS), to reduce their stomach cramps and aches, too — so it goes both ways. 4. Dizziness Some types of antidepressants — tricyclics, MAOIS and SNRIs — are associated with dizziness and issues with balance and the inner ear. Why? We’re not sure. Vertigo usually happens when the inner ear doesn’t get enough blood, but we don’t think that these drugs create a problem with the inner ear itself — rather, it seems like they mess with the part of the nervous system that processes information about balance. 5. Bizarre Dreams It may seem far-fetched that an antidepressant could actually affect the content of your dreams, but it ain’t science fiction — it’s true. Many antidepressants impact sleep patterns, and what’s more, different ones do different things. A study found that SSRIs and SNRIs increase dream intensity and nightmare frequency, while people taking tricyclic antidepressants report happier dreams and were more able to remember their dreams in the morning. 6. Blurred Vision Blurred vision appears to be a side affect of one kind of antidepressant in particular: the tricyclic family. The probable cause? These drugs fiddle with the uptake of the neurotransmitter acetylcholine, which helps to regulate the amount of moisture in the eye via contractions of the eye muscles. If the neurotransmitter isn’t working properly, your eyes will dry out, potentially blurring your vision in the process. 7. Dry Mouth Feel like you’ve got a mouth full of cotton wool? It’s nothing to worry about: this problem has the same cause as blurred vision. Lessened uptake of the acetylcholine neurotransmitter also inhibits the proper function of your salivary glands, reducing the amount of saliva in your mouth. If you’ve just started tricyclic antidepressants and your mouth feels like sandpaper, try cutting out caffeine, and use products designed to help dry mouths, like mouthwashes and artificial saliva substitutes. So, for once in your life, being farty, dizzy, and sweaty is totally normal. Enjoy it! Images: Cartsen Schertzer/ Flickr, Giphy (7) Source: http://bit.ly/1Rzq4vH
  3. Remeron/mirtazapine is often combined with Effexor or Pristiq, in fact the combination is known as "California Rocket Fuel" in Hollywood apparently. But my pdoc explained to me yesterday that Remeron/mirtazapine can help with the side effects of the other meds, even at an extremely low dose (I'm taking 1/4 of a 15 mg pill of mirtazapine at night and I've had no side effects for 100mg Pristiq daily. Weirdly it seems like I'm having less side effects than at 50mg of Pristiq but that might just be that I've been on the combo longer now). Obviously nobody should take any med without talking to your doctor. But I thought I should pass this information on, because a lot of people don't want to take a regular dose of Remeron due to the weight-gain side effect. My pdoc specifically mentioned that the low-dose Remeron can help with side effects such as sexual side effects, insomnia and agitation. p.s. the usual disclaimer "I am not a medical professional."
  4. Hi all. I have been on lamotrigine for about almost 4 years (400mg/daily) and it has helped my moods so much. The last 2 years I have noticed excessive sweating as well as night sweats. I was also taking Zoloft, so this past January I tapered off of that, but stayed on Lamictal. The daytime sweating got less after going off of the Zoloft, but the night sweats continue. I wake up every night sweating completely through my sheets and clothing. The back of my hair is completely soaked and I wake up shivering. My feet are always cold and I have to wear socks to bed, which I never would do. I have a heater in my room, as well as a fan to help with air circulation. I also notice a very strange ammonia type odor from the sweat. It is something I have never smelled when I am sweating normally. Is anyone else having this type of smell happen when they are sweating through the night? I have even had to double check and sniff the sheets to make sure I didn't wet the bed (which I hadn't). I have had hormone levels checked (I am only 29, yet there was a potential for early onset menopause), thyroid checks, gone to a dermatologist and nothing. I take 400mg at night, but talked to my doctor today and am going down to 300mg. I really hope that lowering the dosage will make the sweating a bit more bearable. Has anyone else experienced horrible night sweats from Lamictal? If so, what helped (if anything)?
  5. Hi Everyone, I'm new to this forum, as I am new to the world of medication. Just looking for some advice and support really, as am struggling through the first few weeks of taking Sertraline, and I think friends and family have had quite enough of me! Quick background: Have suffered with anxiety on and off for the last few years, last year I had a lot of family trouble, then over Christmas (whilst staying with family) I became ill, was told had a type of PVFS (Post viral Fatigue Syndrome) and was to rest up to help it fade. After a month of this I attempted to go back to where I live and work but only made symptoms worse and ended up back with family again. By this point I was very low, had no energy, no desire to get back home and to my job and basically felt as though I was having a breakdown, my emotions were absolutely everywhere. I had always been against taking medication but when my doctor suggested it as an option to help me get back on my feet energy wise it seemed like the time had come to try it out. So I was prescribed 50mg of Sertraline, and I went through the initial two weeks of hell! Severe anxiety, upset stomach, nausea, fatigue, the works! Beyond two weeks these seemed to be easing and I was feeling a little more positive. However a week and a half later I felt as though was going back downhill again and was upped to 100mg which I have now been on for a week. Again, am very nauseous, slightly anxious, and have patches of "brain fog". I was hoping to travel back home and to work this weekend but I can't seem to maintain a mood/sense of feeling ok and well for very long. I thought yesterday that I was improving and that it would be doable but today I struggled out of bed again, and am nauseous and tired. I guess all I want to know really from your experiences on this med how long it will take for the side effects to go and it to kick in properly, from reading I see people say a month to six weeks but I guess I interrupted that by upping my dose again so am i starting from scratch from when I did that?! I just seem to have a constant feeling of malaise, maybe a few hours a day where I feel ok but nowhere near 100% Advice? Experiences? Timeframes?? Any help would be greatly appreciated....
  6. Hi, I have been on Pristiq for 3 weeks now. Lots of side effects that have not subsided yet (spaced out, very tired and wired at the same time, anxiety and tremors, headaches, palpitations). Some days are better than others and on those days I have a bit of hope as far as my depression/bipolar goes. But the past few days I have been in a much deeper depression and I am losing hope again. The side effects are bad as well. My questions are: Is it possible that the med simply has not kicked in yet? Is there hope that it might? Is 3 weeks long enough to know? and Is it possible for these side effects to diminish? Any responses are welcome and appreciated! Thanks, Jen
  7. Hi all, first time poster here. I have never taken anti-depressants until a few weeks ago. I've been going to therapy for a year and my therapist and I discussed my going on medication. He suggested Wellbutrin, as I have S.A.D. and a lot of my depression symptoms involve me having no energy. A few weeks ago I got a prescription from a gp in internal medicine (I can't afford to go to a psychiatrist, they aren't covered by my insurance which I lose in June anyway). He had me take Bupropion XL, 150mg for two weeks then going up to 300mg. I noticed an increase of energy, appetite, and anxiety in the first few days but that tapered off. I've been on it for over 3 weeks, a little over a week with the increased dose. Aside from the side effects above, I don't feel any different. I still feel worthless, no pleasure in anything, crying or being sad for no reason, little motivation to do anything or leave my house (aside from going to work). I've heard mixed things from people; some say I should feel a change by now and I should try something else. Others say it gets worse before it gets better. I have an appointment with my gp in less than 2 weeks, so I'm not sure if I should try to get on a SNRI (since I have dysthemia AND anxiety issues) or wait it out with the Bupropion. What do you all think, from your experience with this drug? Like I said this is the first anti-depressant I've ever taken so I have no idea what "better" would feel like. Thanks in advance for any replies.
  8. I have been suffering from low grade nausea most of the time that I have been on Zoloft. I had the same problem with Lexapro. I was having trouble sleeping tonight because I was feeling a bit nauseous and a bit agitated. As I wandered around cyberspace, I stumbled upon an article about ginger being as good as anti-nausea medications for morning sickness, motion sickness and chemotherapy. After, I went and tried a ginger beverage. 20 minutes later my stomach feels a lot more settled, and I feel almost relaxed. I would really like to know whether anyone else has found any simple little tricks like this that have helped alleviate side effects and make life a bit more bearable.
  9. I've been on Zoloft (Apo-Sertraline) 100 mg twice daily and I've been recently researching various side effects of the medication. I discovered that lack of sex drive and excessive sweating are two of the major side effects of the medication. My mother and partner have both commented on my excessive sweating (mostly around the face). My partner and I have also been struggling with our sex life. I was just wondering if anyone's doctors actually informed them about the side effects and were you given an option in the medication prescribed? I was prescribed Zoloft during a hospitalization and I have just realized that my doctor never discussed side effects or alternative options with me. I'm just concerned about the side effects (the sweating is particularly embarassing; on my wedding day I had bridesmaids mopping me off all day). A side note, I'm not over weight or have any other conditions that would produce this kind of sweating. Should I deal with the side effects? Should I speak with a doctor/psychiatrist? I am not currently under the care of a psychiatrist and my GP has been prescribing my medication. I'm just interested to hear other people's opinions.
  10. Hi guys, I have been on different meds for years now for psychotic depression, among other things. But I try to keep smiling and to keep others laughing. So, the other evening, after reading through some of my medication leaflets, I wrote what is intended to be a humorous poem about them. I then filmed it. You can pm me for the video. I only hope it makes some of you laugh and cheers you up. Peace and love, Kris
  11. I finally subscribed after reading different topics and always wanting to jump in. I have been "at this" now for about 26 years, but it was only 10 years ago I was finally diagnosed with bi polar disease. I feel like an old hat at this, but why can't I get a grip on it? I am STILL in the midst of a depression, getting out of major depression, and I suspect one of the medicines and or the depression has made my mind Swiss cheese. I am 44, single mother, unemployed at the moment and just can't get it together to get back to work. Kids are 12, 11 and 10. And we have a typical love hate relationship due to my poor parenting skills as a manic depressive. It just seems like I have finally gotten off the roller coaster and am dealing with the devastation and seeing my life and who I am for the first time. I feel ... Arrrrggggghhhh...frustrated. And it scares me.
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