I'm on Effexor XR 37.5 mg once a day - on it for a month. I know from a thread here (from about 2 years ago) that a couple of others have experienced this zombie-like effect. I had it with Paxil, too. I just want to sleep all the time, it's hard for me to do anything. I force myself to get to work but just can't wait to get home and get into bed again. I have noticed I no longer get hives every day and I'm not having any suicidal thoughts, although anxiety levels and other issues feel the same - I think it's mostly because I'm not having any motivation to do anything! I tried taking it at night instead of in the morning to see if it made a difference, and no luck. So weak and tired. I don't want to continue to be a guinea pig for another month if this extreme tiredness will not go away. Any others with this experience? Does it go away? Thanks so much. Note: I had this exact same problem on Paxil - but even more zombie-like on that. Wellbutrin was a dream... at first. Then I got uncontrollably itchy all over my body every day, and vivid bad dreams. Please don't tell me to 'talk to my doctor' - I'm wondering about actual personal experiences others have had. Thanks!