Oh my gosh! I am so glad I am not the only one! I started taking generic Zoloft about a week ago, after being on Prozac for 8 years. I found the fluoxetine was a culprit in my chronic headaches, and weight gain, though my depression and OCD were well controlled. I CAN NOT cool off! I feel like I am radiating my own heat, and exactly how you described - muggy. The air conditioner is on to a degree that a few weeks ago would have made me chilly. Not only is this going to be expensive, but it's quite humiliating to be at work, working with a client and be sweating profusely for no reason. Does anyone know if this goes away? I don't think this is the drug for me, if this insane sweating and overheating is permanent. Any insight greatly welcomed!