TRINTELLIX (vortioxetine) in Other Depression and Anxiety Medications Posted August 14 c4n4y Did you find the nausea subsided any with the lower dose of 5 mg? I quit taking 10 mg because it felt like my stomach was going to burn out of me. Very uncomfortable. I did find that was the only bad effect and the improvement in my MDD & Anxiety was good. I recently started taking it again because I was so bothered by the falling/dropping sensation from my anxiety. I have tried anti nausea pills and Gaviscon antacid to help, but nothing really stops the stomach issue completely. I find the sexual effects of Trintellex to be minimal, but not zero. I was also bothered by finishing the job. I must say that my falling/dropping sensation was gone in 2 days, maybe I could use a lower dose and avoid the side effects. I'll. talk to my doc about that soon.