Hi Castiel, I've had that happened plenty of times, even with meds. It could be that the medication has a placebo effect, and/or you expect to work because you want it to. I've had to go back to the drawing board all over again. It sucks and it's difficult, but it's a process. Also, some times the meds will take longer than 2 weeks to kick in, I've heard up to 4 (groan). In the past, I've had to have a lot of patience with the process of finding the right meds, if that is what you are doing (sounds like). You have to keep checking in with your pdoc. I completely understand in regards to the social anxiety. I'm totally not that bubbly, talky kind of person, more quiet and reserved, and have sat by myself plenty of times. It's sooo awkward, I know. To a certain degree, embracing and accepting it has helped, and finding another person like myself if it's possible. Not every one is the bubbly, extroverted type. I'm sorry you had to quit your job. Maybe it was not the right one for you at this time. Hang in there, you're not alone.