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I’ve been on Sertraline for awhile now, for anxiety and depression and it works well. 50mg was my first dosage, with anxiety being my major side affect. My psychiatrist slowly raised my dosage to 150mg over 7 weeks before I felt better, it usually takes that long. I think it’s great to discuss your side affect, and dosage level with your doctor, and discuss another medication, as frustrating as it can be.

Good luck. Sertraline has always worked for me.

My doctor always started me at 50mg and then slowly increased it

I've been taking 50 mg of Zoloft for 16 days but still experience anxiety. How long does it usually take for the Zoloft to kick in enough to ease the anxiety?

Hi, thanks for the input. I wish my doctor had suggested starting at 25mg from the beginning. By the time I read the recommendations I was already into 8 days at 50mg and didn't want to backtrack. By day 10 my anxiety started to subside and I'm hoping the other side effects continue to improve shortly.

I started Zoloft 7 days ago for depression (50mg) and have been feeling anxious and have no interest in anything not any appetite. My doctor gave me Xanex for sleep but nothing for the anxiety. I hope things improve. It's been hard to handle.