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Everything posted by mikl_pls

  1. I can't help but feel like this website/community is barren. It seems like a lot of people create an account, post one question, and never come back to follow up with us. When I was with crazyboards.org (they kicked me out for giving too much information), the community was way more tight-knit and everyone knew each other. I feel like it's very clique-ish here and like I don't belong here at all. I don't feel like blogging about this is going to help either since no one commented on my last blog. But whatever. C'est la vie. This too shall pass.
  2. TW: overdose Sunday I quit my job that I had only had for 2 weeks at Walgreens. I was supposed to be a pharmacy tech, but they put me on the front and had me scheduled there through xmas. My pharmacy tech license was still on the office desk with junk piling on top of it. I knew it was going to be stressful, but I didn't know they were going to throw me into the lion's den with virtually no training. Everything on the cash register I learned, I learned on my own (through trial and error). I had minimal training on stocking, facing, and pulling tags. I never finished my PPLs because I kept coming in and being put on register. We're not supposed to leave the register unattended, yet when a customer asks where something is, you have to walk with them at their pace where it is and show it to them (I didn't know where most things were) and ask if there's anything else they need help finding. My last day, I was asked not to take a lunch by my shift lead. Her blood sugar was in the 400's (she's diabetic type 1). I had had a simple-partial seizure earlier, and a tonic-clonic the night before. I think it was because of my disrupted sleep, constantly shifting hours, and mounting stress. I got home and my best friend tried his best to console me and comfort me, and things looked like they were going to be okay. After he left, though, I got to thinking about how I was going to confront my manager about the working conditions. I dreaded it more and more to the point where I took about 30 mg of Xanax. I didn't wake up until 5 PM the next day. I saw I had a text on my phone from my boss, saying "you're on the schedule 9-5, call me asap." I responded by flaming her for the work conditions and told her I quit. I shouldn't have done that... Looks like I will no longer be able to work at Walgreens anywhere again. If anyone is reading this, does anyone have any recommendations for decently paying jobs that won't **** me? I'd prefer to do pharmacy tech since I did spend the $104 on the license, but it doesn't have to be.
  3. Maybe you can tell her your experience with the other doctor and ask if she knows of another one to recommend? If not, you can find a list of doctors and psychiatrists your insurance covers on your insurance website. Just do some research online about the doctors before you call their office. That's unfortunate... Abilify is supposed to be weight neutral, but it can cause weight gain in an unlucky minority of patents. Have you tried Vraylar before? The very least she could do for your ADHD is try Strattera (a non-stimulant, selective norepinephrine reuptake inhibitor). I will say that the generic is pretty crappy IME. But if you start on generic you should be fine.
  4. Are you on Wellbutrin SR (150 mg twice daily), Wellbutrin XL (300 mg in the AM once daily), or (not likely) the instant release Wellbutrin (100 mg 3 times per day)? If you're on the instant-release or SR, you can go up to 400 mg/day with 100 mg IR 2 twice daily or 200 mg SR twice daily. If you're on XL, you can go up to 450 mg, either by taking 3 150 mg tablets or adding a 150 mg SR or 2 75 mg IR tablet(s) to it. There's also two brand-name formulations of Wellbutrin at the 450 mg dose. Forfivo XL 450 mg is a once daily extended-release tablet, and Aplenzin is a different salt of bupropion (bromide instead of hydrochloride) and the 522 mg dose of Aplenzin is equivalent to 450 mg of Wellbutrin XL/Forfivo XL. Some say Aplenzin is "smoother" than the hydrochloride salt version, so you may wish to ask about this version of it, but make sure your insurance covers one or both of those before asking your doctor for a script for it—insurance companies don't like to cover those brands anymore... It doesn't make sense for Aplenzin, sorta kinda makes sense with Forfivo XL though... Alternately, while not commonly used for depression, a stimulant could be used to augment the noradrenergic and dopaminergic effects of Wellbutrin. Ritalin (plus other products/brands, as well as Focalin) is an NDRI like Wellbutrin but more potent, and amphetamine-based products (Adderall, Dexedrine, Evekeo, Vyvanse, Desoxyn, etc.) rather cause your brain to "squeeze out" the norepinephrine and dopamine (and to a lesser degree serotonin) from storage vesicles into the synapse as well as causing mild reuptake inhibition and in higher doses, monoamine oxidase (MAO) inhibition. Some respond to both, some respond to the Ritalin-based ones and not the amphetamine-based ones, and vice versa... Just gotta try them if your doctor is on board with it.
  5. Sounds like that psychiatrist is not the one for you, and you might consider trying to find another one (I know, it's hard...) Some general practitioners are willing to prescribe ADHD meds (stimulants) for a brief time until you can get in with a psychiatrist. Also could be a lame excuse to not prescribe stimulants because she "doesn't believe they're safe" or whatever. -rolls eyes- Theoretiically Abilify should improve ADHD, but that's just on paper. Abilify is not like other antipsychotics. It is a "dopamine partial agonist" (it partially stimulates dopamine receptors) rather than a "dopamine antagonist" (dopamine receptor blocker). Its "intrinsic activity" (the percentage that it stimulates the receptor) is about 70% or more at the D2 dopamine receptor (the main one they look at for antipsychotic effectiveness), so it's pretty potent. What dose are you on? Lower doses (2-5 mg) tend to be rather stimulating, and are usually the first doses people take of Abilify. If you can stick it out through the initial dose increasing, if you can make it to 10-15 mg, or at least 7.5 mg (half a 15 mg tablet), it "calms down" more at those doses and you won't feel so "coked out." This was definitely the experience I had with it when I was on it. Beware though that it can cause impulse control problems (gambling, shopping, hypersexuality, etc.). I was one of the unlucky few who was affected this way and I developed a compulsive shopping/spending habit which ruined me financially. There's literally a class action lawsuit and a black box warning for both Abilify and Rexulti (same company) for this. It doesn't happen often, but it's a possibility to beware of. Perhaps your psychiatrist could prescribe you something like trazodone for sleep? Have you ever taken that? It's an older, sedating antidepressant (no weight gain or sexual side effects or anything) in the "SARI" (serotonin antagonist and reuptake inhibitor) class. At low doses (like 50 mg), it's used as a hypnotic to help you sleep and even help with anxiety. In higher doses (300+ mg) it's used as an antidepressant (supposedly a rather crappy one at that). Not trying to tell you what to do with your meds, but just a suggestion.
  6. Typically, for most SSRIs and SNRIs, it's 2 weeks for a thorough washout. If you want to get technical about it and do it the mathematical way, find out what the half-life is of the medicine and multiply it by 5. (If it's a range of time, like 72-96 hours, you can do both numbers or do an average...) So 5 half-lives is how long it takes for a medicine to either leave your system after you stop taking it, or reach steady state after you start a medicine or new dose of medicine. For example: Fluoxetine (Prozac) has a half-life of 4-6 days (average 5 days), while its active metabolite, norfluoxetine (which contributes to the activity of the medicine), has a half-life of 9.3 days. Fluoxetine: 5 days • 5 half-liives = 25 days (3 weeks + 4 days) Norfluoxetine: 9.7 days • 5 half-lives = 48.5 days (6 weeks + 6.5 days)
  7. I wouldn't say so. Prozac takes a long time to clear from your body completely, about 5 weeks minimum, so you still had some Prozac in your body while you were trialing this other drug. The appetite suppressing effects tend to show up in the higher doses, like 60-80 mg.
  8. Chances are you'll feel it within the next few weeks (after posting—I know this is a bit of an older post). That's at least from my experience anyway, and from what my pdoc told me. The true, true benefits of Cymbalta didn't unveil themselves for me until I got to 120 mg, which is what I'm on now. That doesn't mean you should go ask your doctor for 120 mg though. Give the 90 mg a good college try, because if you hit 120 mg, you'll have no more room to go up (except some docs prescribe up to 240 mg sometimes).
  9. I had a good experience with that combo for a short while.
  10. This is a normal side effect for Cymbalta. You can take a medication called "glycopyrrolate" to help ease the sweating.
  11. Strange. I've personally never heard of that from Latuda, but that doesn't mean it isn't a thing... lol. I'm more on the side that it's continuing depression. Thanks! I hope you're doing well too! Hydroxyzine could contribute, but more likely it could help you feel better because you're getting better sleep and it has 5-HT2A antagonism.
  12. Interesting. Latuda isn't well-known for causing that flatness you're speaking of, but it's certainly not out of the question. Hydroxyzine is definitely pretty sedating for many people. Make sure you are taking the Latuda with food (at least 350 calories of food) to ensure its absorption. My pdoc always prescribes it to take in the evening with supper. I hope it works out for you. :) If you continue to feel flat, you may ask about going down to 20 mg perhaps...
  13. Seems like your tapering is getting easier, am I right? Keep us updated!
  14. He needs to either get back on the fluphenazine (Prolixin) or switch to something else if the blurry vision is really bothering him. Something less anticholinergic, perhaps. I recommend trifluoperazine (Stelazine) if he's going to take a first generation antipsychotic, but it can be hard to find a pharmacy that can get it since it's kinda rarely prescribed and not many companies make it anymore. Haloperidol (Haldol) is an okay temporary to get by, as it's VERY strong, but rates of tardive dyskinesia are highest probably for this antipsychotic. Fluphenazine is basically Haldol without the bad side effects (it's a phenothiazine though as opposed to being a butyrophenone like Haldol).
  15. Nope, no problem mixing the two. Pepcid is in the same class as Zantac, just with less side effects and less drug-drug interactions. It's about time they pulled Zantac... Good luck with Pepcid! IMO, it's the best H2-histamine antagonist antacid. You can get this prescribed by your doc and it's way cheaper.
  16. Many illnesses increase inflammatory markers, and depression is thought by many to be an inflammatory disease in the first place. Increased inflammatory markers can lead to depression, and certain people are very sensitive to this, like when they get sick, and so they subsequently feel depressed. By now you must be over your illness, so if you're still depressed, I'd pay a visit to your doc/pdoc.
  17. Seroxat (paroxetine) can have this effect on people. Sounds like you need to try an SSRI with a more mood-brightening and stimulating effect, like fluoxetine or sertraline, or even an SNRI.
  18. Latuda can be stimulating (or agitating) at low doses (20-40 mg), so if you feel that way, your pdoc may increase the dose to 60-80 mg, or even 120 mg if needed. The max dose is 160 mg, but that's for schizophrenia. Good luck with Vraylar, I just got off it because it was making me feel more depressed. Start at 1.5 mg and keep it there as long as you can if you're taking it for depression. Also, too much Lamictal can make you feel flat and emotionless, which can be mistaken for depression, so unless you take it for seizures, you may discuss with your pdoc taking less Lamictal. Just an idea.
  19. Actually, this could mean that you are a poor metabolizer of either CYP1A2 or CYP2D6, liver enzymes responsible for metabolizing Cymbalta. Either that, or your serotonin transporter (SERT) genes are such that you are sensitive to serotonergic drugs. Why not try 20 mg for a while, then try the every other day, and so forth? Best of luck titrating off of it! It can be a doozy.
  20. Psychedelics mainly work on the serotonergic systems, so it could be that you have downregulated your 5-HT2A receptors especially (the main receptor psychedelics work at to produce hallucinogenic effects), which is actually a good thing. The fact that your antidepressant isn't working as well as it used to has me baffled though. I honestly don't have an answer to this. Have you tried escitalopram (Lexapro) before? It's basically half of the molecule (the good half) of Celexa (less side effects and more potent). Any other SSRIs tried? You might benefit from a beta-blocker, especially one like propranolol (Inderal) or pindolol (Visken). These relieve the somatic symptoms of anxiety (like chest pain, stomach queasiness, etc.) Pindolol actually can help accelerate the response to your antidepressant via 5-HT1A antagonism or low instrinsic activity partial agonism (functional antagonism). 5 mg is usually all that is needed, but sometimes 7.5-10 mg is needed. Propranolol is also great for anxiety, not so much for depression, which actually can be a side effect of it. Most people in your situation maybe only need 10 mg twice daily as needed or 20 mg twice daily as needed. I personally don't, but one of my best friends does, and he said that from his experience, psychedelics and serotonergic drugs do not mix well with each other (unfortunately, IMO... not trying to encourage psychedelic use or anything...). MDMA's effects are actually is rendered null by serotonergic antidepressants (anything that has serotonin reuptake inhibition), and can be lethal to take with an MAOI, so there's that. LSD is the same way. Psilocybin I'm not so sure about. Are you sure you're not bipolar?
  21. So God is non-binary according to this minister, if I have that terminology correct. Or androgynous? I think non-binary is neither nor, and androgynous is both at the same time. Makes sense to me. If s/he/it is omnipresent, omnipotent, etc., then it would be everything relating to sexual traits/secondary sexual traits as far as we know. Regardless of sex/gender/whatever, I believe God is God, and even believe there may be multiple Gods. I'm agnostic, so I don't claim to "know" who or what God is. I believe God is beyond our capability of comprehension because it is an infinite being—here forever before and will be forever after humans. That's just my opinion. I grew up Christian, but because of circumstances beyond my control, and a very toxic church environment, I stopped going to church and my religious orientation changed. Thank you, I truly felt safe and reassured as I was going through a difficult time when I felt that presence. I wish to feel it again whatever or whoever it was. I really hope bible verses are not going to be thrown at me for what I said. These are just my beliefs, and I wish for them to be respected just as I respect all of your beliefs.
  22. I think I saw this post on CB, but I'll go ahead and respond to it again. I used to get benign rashes all the time on Lamictal. I went to the doctor the first time I got a rash freaking out about it being SJS. He smiled and assured me it wasn't SJS. SJS has a distinctive appearance with splotchiness on the skin and severely inflamed mucous membranes. If you want to know what it looks like and have a strong stomach, use Google Image Search to see what SJS looks like. Note that these will mostly be advanced cases that have gone untreated for a while, "a while" being very relative as SJS progresses very quickly. All this being said, as has already been said, take any rash very seriously with Lamictal, as a benign rash could easily turn into a malignant one. Hope you're doing okay on the Lamictal!
  23. I have felt a presence that I felt was divine. It was a motherly, nurturing presence. Not sure if it was god or an angel.
  24. Unfortunately there are no authorized generics (equivalent to brand-name) for fluoxetine. It's probably going to be a crap shoot as to finding a generic that works for you. I actually didn't even know they made brand-name Prozac still. Interesting.
  25. I second what has been already said: Prozac has a long half-life and would theoretically create its own taper, but it would be prudent to taper off if you've been on it for a long time, and if it's been only 9 days you shouldn't have any problems coming off of it cold-turkey. The anxiety you're experiencing is very common with SSRIs, especially with Prozac, in the beginning. If you can stick it out, it will get better and you will likely get relief from your symptoms.
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