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About mikl_pls

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    Junior Member
  • Birthday 09/11/1987

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    Alabama, US

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  1. mikl_pls

    Vibryd not working for me.

    Definitely, talk to your doctor.
  2. mikl_pls

    Just moved to 30mg. Questions.

    I would discuss these symptoms with your pdoc. I personally never experienced those symptoms on Viibryd.
  3. You probably meant 37.5 mg. 37.5 mg is the smallest dose of Effexor XR, and is, at that dose, essentially an SSRI. It doesn't become an SNRI until around 150-225 mg, so you'd need to go up on the dosage a good bit to get the norepinephrine benefits from it. If you want to mitigate the sexual side effects, you could try asking for a prescription for low dose trazodone (to help you sleep), nefazodone (watch out for liver toxicity), Remeron (watch out for weight gain), or just go straight for a PDE5 inhibitor like Viagra or Cialis.
  4. Maybe you just need an additional 37.5 mg...
  5. mikl_pls

    Abilify caused hypomania

    Low doses of Abilify can be activating while higher doses tend to be calming. Chances are you were on a low dose and it activated you into a hypomanic state. If you had stuck with it and increased your dose, you would have evened out. Maybe you might try something like Lamictal as an add-on? It's an anticonvulsant but it acts as an antidepressant mood stabilizer.
  6. mikl_pls

    Major life event, not doing well.

    What's your Viibryd dose? Are you all the way up to 40 mg? My pdoc said some people need as much as 80 mg... I'm not a professional, so please take this with a grain of salt, but it sounds like it could be situational. You might want to discuss it with your pdoc and ask for their opinion, maybe even start seeing a therapist—it could be that seeing a therapist would be more beneficial than switching or tweaking your meds. Wishing you the best!
  7. mikl_pls

    Will Remeron help with SSRI apathy???

    Abilify is very activating for most people in low doses (2-5 mg) and even 10-15 mg for some people, but any higher than that (20-30 mg) it will likely become a bit calming or even sedating. For some people, even the 10-15 mg doses can be calming/sedating, but in my experience, it was stimulating all the way up to 15 mg, but I got akathisia at 15 mg and had to discontinue it. I wish you the best of luck with Abilify! If Abilify happens to poop out on you, you might check out Rexulti or Vraylar because they act in a similar manner, but are less stimulating than Abilify (well, they were for me anyway).
  8. That's an awfully long time until your next appointment and an awfully long time to deal with a medicine at the max dose which doesn't seem to be working. If you've been on Celexa since the beginning of this year... 7 months... if it would work for you, it should've worked by now. At the very most, SSRIs take about 6-8 weeks to work, but usually a little less than that. I don't understand why she refused to switch antidepressants for you, that seems almost atrocious, especially with your appointments so spaced out. Is there any way you can get a work-in appointment with her? If so, if it were me, I would insist on changing medicines, citing that SSRIs should take, at the most, up to 6-8 weeks to start working, and it is well past time for it to have started working. I don't know which antidepressants you've tried before, but Lexapro is the S-enantiomer of Celexa, which basically means it's more potent (Lexapro 10 mg = Celexa 40 mg, Lexapro 20 mg = Celexa 80 mg—beyond max dose of Celexa). Lexapro is a general run of the mill SSRI and is generally well-tolerated with minimal, innocuous side effects. Zoloft was pretty good for me (but pooped out rather quickly since I'm bipolar), but has worked wondrous miracles for my one of my best friends. It does very well for atypical depression, characterized by symptoms like excessive fatigue/oversleeping, excessive appetite, apathy, but it tends to be a little stimulating though, so if you're a high-anxiety person, you might want to start at a low dose and go up slowly (Celexa 40 mg ~ Zoloft 50 mg, so you might want to ask for enough 50 mg tablets to titrate up to somewhere around 100 mg and break them in half for 25 mg and go up by 25 mg increments; otherwise, if you don't have an issue with anxiety or want to titrate faster, you could go up in 50 mg increments). In the end, though, it is highly beneficial for anxiety. Prozac is another one that tends to be good for depression associated with atypical depression, but is also stimulating, probably more so than Zoloft (Celexa 40 mg ~ Prozac 20 mg). But it does well for anxiety, too, if you can tolerate the starting side effects. Paxil is great if you have anxiety as it tends to be rather calming (although I've never taken it so I can't speak with personal experience). I've read that it tends to cause weight gain, though, and has a bad withdrawal syndrome should you ever chose to switch or stop taking it. Luvox is indicated for OCD, and Luvox CR for social anxiety disorder, but it's commonly used off-label for depression. I didn't have a good experience with this one, but your mileage may vary. If you've taken most or all of these, you might want to try an SNRI, which also tend to be somewhat stimulating. This includes Effexor XR, Cymbalta, Pristiq, and Fetzima. The first three are generic, but the last one is brand-name only. There are also the SMSs, but they are brand-name only. These include Viibryd and Trintellix. One caveat is that these are associated with GI side effects (which I didn't experience when I took them except for Trintellix, which cause quite a bit of nausea while I was on it). For the antidepressants that are brand-name only, there are copay coupons on their websites, but your pdoc should have copay coupons available to give to you, even samples to get you started on them. I hope you can get some relief soon! Take care!
  9. mikl_pls

    Hand Tremors

    Yes, when I was on Wellbutrin my hands tremored quite a bit. Also, for some reason, Lamictal makes me hands tremor like crazy, like, enough to where strangers ask "are you okay?" It's really embarrassing... lol.
  10. mikl_pls

    Get back on abilify after 3 weeks?

    Verey nice! I'll probably ask about that next time I see my gdoc.
  11. mikl_pls

    Hand Tremors

    Propranolol or nadolol ought to do the trick for the tremors. Either that or primidone. Or both.
  12. I was about to say a common combination is Prozac and Trilfon (perphenazine), a first-gen antipsychotic, which acts as an antiemetic and anxiolytic. Compazine (prochlorperazine) works well too, as well as ondansetron (Zofran). The antipsychotics just seem to work faster for me.
  13. You probably won't have to wean off Effexor if you want to switch to Cymbalta. You can probably just hot-swap one for the other. 225 mg Effexor is about equivalent to 60-90 mg Cymbalta I think. Cymbalta actually has an indication for FM, whereas I don't think Effexor does, so I don't see why your pdoc is so concerned about switching you.
  14. I don't have any experience with citalopram, but I do have (bad) experience with escitalopram. I can tell you that according to Stephen Stahl, 40 mg citalopram = 10 mg escitalopram. So perhaps you could try cutting the escitalopram in half for 5 mg at first and take that until you get used to it and then step up to 10 mg?
  15. Wow, that's a rather rapid titration for Abilify! Are you manic? Typically Abilify is stimulating in lower doses (like 2-5 mg) and becomes relaxing or even sedating in the higher doses (10 mg and above), but it varies for some people. I think you are just titrating way too rapidly on the Abilify. I have no idea why your pdoc has you going up on it so rapidly unless you're manic and it's an emergency. Especially going from a sedating med like quetiapine. Do you just have 15 mg tablets? I'm not going to tell you how to take your medicine, but I'll tell you what I would do in your situation. Abilify has a long half-life, so you could get away with cutting the 15 mg tablets in half for 7.5 mg and take them every other day for a few weeks, then start taking them every day, then start the 15 mg tablets either every other day for a few weeks or every day. Whatever you're comfortable with. And meanwhile, down-titrate off the quetiapine as slowly and comfortably as you need. That's my 2 cents worth on the situation. If Abilify continues to give you agitation, perhaps your pdoc could prescribe you an anticholinergic like benztropine or trihexyphenidyl, a beta-blocker like propranolol or nadolol, and/or a benzo like lorazepam, diazepam, clonazepam, etc.