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  1. Great to hear your getting quality sleep. I was on Mirt for a few years (came off four years ago or so) and had the best affect on the 15 mg dose. I noticed a very positive uptick in mood after about 4-6 weeks which I think was due to the consistent restorative sleep. The dreams were incredible. I think your depression / anxiety will really improve in the next couple weeks like mine did on that dose. It was a really good med for me. Good Luck and Im sending you positive vibes.
  2. Hi Breezy I had great success with mirtazapine for a couple years and like you eventually wanted to try to come off because i did feel a little slow and sluggish during the day. I tried cold turkey but my sleep really suffered and my mood really tanked, depression and anxiety came back and I had to go back on. I tried again a few months later and was able to come off by slowly tapering down over a course of a a few months. Each time I made a reduction my mood would drop but if I gave it time I would eventually come around. I think that by gradually reducing your dose over a course of a few months it gives your brain a chance to adjust and lessons the withdrawal symptoms. Each time Id make a reduction I would stay at the same dose until I didnt have withdrawal symptoms for atleast a couple weeks. I think I went to 7.5 mg for a month. Then to 3.25mg for a month. Than I believe 1.5mg every other day for another month and then I stopped. So all in all it took about three months for me to quit if I remember correctly. I do remember feeling like crap after each reduction for a period of time before feeling better.
  3. I can relate to what your going through. I also have experienced very bad reactions to medications that once worked for me in the past. One med caused depersonalization that felt like it would last forever. It was very scary at first and felt like I would be that way forever. But over time it slowly started to go away and I began feeling better. Our brains are neuro plastic and will heal itself you need to give it time. Reduce stress as much as you can and take walks in fresh air when you have the energy. Be kind to yourself, be aware, and give your brain a chance to heal. No brain state (good or bad) lasts forever. Make sure to get the best sleep you can. ''This too shall pass"" .
  4. Yes its a normal side effect for some people and usually goes away after a few weeks. ( Something about the serotonin receptors down regulating and/or becoming desensitized). I know when I started Pristiq (chemical cousin to Effexor) I had increased anxiety for a period of time and then started to feel relief after about a month or so.. Start up periods for medications can suck but it does get better. If the start up anxiety gets to a point where it is unbearable then you should see your doctor for a new plan forward. I hope this helps and you find relief soon. Take care
  5. Hi Not a whole lot you can do about the morning grogginess. I found that getting everything ready for your day the night before helped to make mornings easier.. Lots of Coffee. The morning grogginess and daytime lethargy goes away in about a month once your body adapts to the med. The first couple weeks are the toughest but it gets better. I had incredible dreams when I started the med do you have this side effect. I really enjoyed the dreams . going to bed was like getting ready to go to a drive in theatre. lol and food tasted way better. Good luck I hope you get benefits with it.
  6. Hi Strangebird, I think there's a really good chance that your side effects will fade in time once your body adapts to the medication. it can take a good 6-8 weeks though. Good luck.
  7. I can relate to what your going through. I have to be very strict with my diet so that I don't gain too much.Im on Remeron and Pristiq. I do my best to avoid added sugars,bread,pasta, desserts. I m surprised your doctor thinks that lamotrigine is the culprit for your weight gain because usually that's a weight neutral med. Your weight increasing is more likely the aripiprazole and or the escitalopram. The aripiprazole can play with blood sugar and cause cravings. The idea is you should try and get yourself in a position where your taking the least amount (doseage) of the meds to control your mood and reap the benefits while at the same time eating as healthy as you can to minimize weight gain side effects of the meds. Some people gain on these meds and some don't. More research is coming out that high sugar and carbohydrate (not fats) diets is whats causing the obesity crisis in America. Try to cut back on simple carbs (added sugar,fruit juices, ) Georgia Ede has a great website. Shes a psychiatrist who promotes a ketogenic diet and shes seeing great results from her clients. Check out her website its www.diagnosisdiet.com. She has some great lectures on diet on youtube too. I like her because shes one of the few psychiatrists that is also knowledgeable about diet and nutrition. Good luck Im sure youll find the healthy balance your looking for.
  8. Hi! I take Pristiq I find its the best med out of the ones Ive tried. It keeps me a little more calm and content not as worked up and anxious. I would definitely give it atleast a month on its own away from Wellbutrin to let your body settle in to the med. Your probably experiencing Pristiq start up side effects along with Wellbutrin withdrawal side effects. If it were me Id stay the course on Pristiq unless the energy was unbearable and then Id contact my Doc but give it time it could be a good med for you. Good luck my friend
  9. Hello Ladysmurf I think the new medications will be very helpful for some people for sure. Lots of new scientific research being done on the brain and gut microbiome connection as well as on inflammation. If you have a chance check out Dr. Charles Raison and Dr. Rhonda Patrick youtube podcast lots of new info on depression. Its thought that genes that turn on and are causing mood disorders are also the same genes that when turned on can resist certain viruses. Its like a defense system the brain, body naturally goes into. Also check out Georgia Ede. Shes a Harvard trained psychiatrist. Shes seeing huge benefits with her clients who adopt a ketogenic and or all meat diet. Im trying the all meat diet and it s been about three weeks and I do notice a reduction in anxiety so Im hopefull Itll continue.
  10. Hi Troutmask Ive been on Remeron for a couple years now and ive gone through what you describe a few times while introducing other meds in the mix. Anytime Ive discontinued a med that interfered with sleep it would take me a longtime for the Remeron to work again. Rogaine has a crazy long half life so it might take you a bit longer but youll get there for sure. Good luck Take care
  11. Hi peaches I m on Pristiq and I feel like its helped. After two months I feel like its lessened my anxiety and irritability and made me a little more content. Its not a cure all but im better than I was. Its the best antidepressant ive tried I think. The one problem I was having with Pristiq was I wasn't absorbing it all. ( gross alert, I had to check my stool and found medication in the capsule ) I fixed this problem by putting the pristiq pill in a glass of water the night before(take the pill and drink the water the next morning) I think it helps soften the outer shell so your body can get at the medication .Anyhow Im on 100mg. The start up effects I had with Pristiq were increased anxiety ,insomnia. It does get better and is worth getting over the start up side effects to see if its a good suit for you.I would say for me that it took about a month before I started seeing benefits of the med. I think its really encouraging that you had a genesight test done that showed it suits your chemistry . Im sending you positive vibes and hope that Pristiq is the med for you. Feel free to message me if you have any questions Good luck.
  12. Some people can come off mirtazapine with little side effects (its usually the easiest med to taper). Some people find it very hard and I'm one of them. I dropped my dose from 15 to 7.5 and felt okay for a month and then bam got hit with withdrawal. I ride it out and do my best to stick with the reduced dose. I don't make any further reductions until all withdrawal symptoms are gone and then reduce very slowly. I think genetics plays a huge part in how we react to medication and withdrawal. I hope you start feeling better soon. FWIW after making the reduction to 7.5 Ive stayed there for a couple months now and plan to reduce it by 10 percent maybe every month or so.
  13. I put the pristiq pill in a cup of water the night before and it softens the outer shell and then take it the following day. I drink the water as well and take the pill. I think its working(absorbing) so far.
  14. Don't be afraid of Remeron its a great drug for many people. Its also easier for most people to taper off of when the time comes. In my opinion Remeron is the best antidepressant for anxious insomniacs. The drowsiness,dry mouth,lethargy is tough at first but it does get better with time and most if not all side effects go away in about a month. Remeron brought me out of a pit of despair when no other medication could. I stayed on 15mg. I think it was the deep sleep that helped restore my brain because I was on a sub therapeutic dose but still saw a lot of benefits. The dreams are amazing too.
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