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  1. 5-HTP will make you tired and sleepy (it converts to serotonin which converts to melatonin), so I always take it before bed. I've been taking 100mg 5-HTP + 25mg B6 (P-5-P) for quite a while now and I like the effects.
  2. I take 5-HTP at night and L-Tyrosine during the day and I think it's a good combination. I take them both with vitamin B6 (P-5-P). It's more effective than any other prescription antidepressant that I've taken. Do you remember where you read this? From what I understand, 5-HTP should always be taken with B6 (P-5-P). Dr. Slagle also recommends this on her website here: http://www.thewayup.com/products/0087.cfm
  3. Hey Cheddarhead, I'm sorry it didn't work out for you, but I just have a few questions... Were you using the P-5-P form of Vitamin B6? This type of regimen won't work unless you take P-5-P with the amino acids. The Tryptophan should also be taken before bed because it does cause drowsiness. Also, were you taking all of this on an empty stomach? Amino acids shouldn't be taken with food because then the amino acids you take will be competing for absorption with the food in your stomach. If you need to be on Zoloft, maybe you could try taking your Zoloft plus L-Tyrosine and P-5-P? I would just talk to you doctor first though.
  4. I've taken a lot of different sleep medications, but the one thing that works best for me is actually magnesium. Magnesium Taurate is good, and so is this brand called Natural Calm, which is a powder that you put in warm water and drink it like tea. Most health food stores sell Natural Calm. But I would avoid the magnesium oxide they sell in grocery stores. Magnesium works just as well as benzodiazepines for me at least for both anxiety and insomnia.
  5. Just an update: I'm about a month into the program now and I'm still feeling incredible. No depression, no anxiety, no fatigue, no brain fog, no insomnia. In fact my cognitive abilities have come back completely. And I continue to have a very positive outlook on my future. Please, if you're reading this and nothing has really worked for your depression and anxiety, look at those books I alluded to in my first post above. This is far safer and far more effective than prescription antidepressants.
  6. I take 5-HTP, L-Tyrosine, a good multivitamin, a good Co-Enzyme B Complex and extra Vitamin C. This combination has basically completely removed my anxiety and depression. I learned about it from this book "The Way Up From Down" by Priscilla Slagle. I made a topic on this in another thread. If you click on my name and view my posts you will find it. Good luck!
  7. I just looked at that multivitamin-mineral you're taking and it looks really good. I like how it has the good form of B12 (methylcobalamin) and I like how it has a high dose of Magnesium (which I hear is absolutely amazing for depression, and I'm going to test it out soon, although since I'm not depressed anymore I don't know if it'll do anything!). The proprietary blend looks good too, I just don't like how companies don't tell you how much of each of those is included. I also consider my multivitamin-mineral to be the foundation of everything. The one I take is just called "M.V.M." and is by Tyson Nutraceuticals. I also avoid gluten (and most carbohydrates), sugar, milk products and alcohol too. I find that sugar absolutely destroys my mood. I also have energy and feel awake all day now, so I've cut my caffeine/coffee intake way down. Have you ever tried taking L-Tyrosine and L-Tryptophan/5-HTP in higher doses? If you're prone to depression, you might find that this combo really pulls you out of it in an amazing way. I'm on day 23 and I haven't felt this good for as long as I can remember.
  8. Great to hear amino acids are working for you too, even though you seem to be doing it a little bit different that I am. It looks like you're taking a blend of all the amino acids, but I'm just focusing on the ones that increase mood neurotransmitter levels. How long have you been taking this for? Are you taking anything else for depression?
  9. Annnnnnnnd....one more correction: I wrote in my first post: "So it's important to take both 5-HTP/L-Tryptophan and also L-Tyrosine, so they are all being increased at once." What I meant to say is: When you take 5-HTP or L-Tryptophan (and you should only take one of these), you should also have L-Tyrosine in your regimen. This ensures that you're not only increasing serotonin (with the 5-HTP or L-Tryptophan), but you'll also be keeping your norepinephrine and dopamine levels up (with L-Tyrosine).
  10. I forgot to mention something pretty important. I have also removed most sugar and caffeine from my diet, and that alone helped immensely with evening out my mood. Both sugar and caffeine deplete the serotonin in your brain, which is not good if you're prone to depression! The L-Tyrosine increases my energy, so I don't even feel much of a need for caffeine any more. You should also not take L-Tryptophan or 5-HTP if you are already on a prescription anti-depressant (especially an SSRI), because they both increase serotonin, and you don't want to get serotonin syndrome! I would just talk your doctor first about tapering off while slowly adding in L-Tyrptophan or 5-HTP.
  11. Hello, I have suffered from depression and anxiety for most of my life. It has gotten really bad at times. I used to be prescribed Prozac, but it stopped working after several years and made me feel functional, but like a zombie. I was then prescribed Zoloft for a few years with the same effect. Because these two SSRI's worked to a degree, I knew I at least had low serotonin, so I began searching for more natural ways of increasing this in my body. I came across a book by Dr. Priscilla Slage called "The Way Up From Down". She offers it as a free PDF on her website. In it, she describes an amino acid and vitamin program that is backed by a good amount of scientific research to heal depression, and not only that, actually make you feel alive and normal. I was skeptical but pretty desperate, so I gave it a try. (I also read another one called "The Mood Cure" by Julia Ross and that has a lot of the same information.) It's only been a little over two weeks now, but even after the first day, I felt my depression lifting. For the past week or so, most of the time I don't even feel depressed, and on top of that I feel my normal self coming back. However, my mood has been up and down, but each day I can feel it getting better and it's more up than down. So this is what I have been taking: 1500 mg L-Tyrosine immediately upon waking on an empty stomach + 50 mg Vitamin B-6 (the Pyridoxine-5-Phosphate / P-5-P form) With breakfast: A pharmaceutical-grade multivitamin, a Co-Enzyme B Complex vitamin, 1000 mg Vitamin C 1500 mg L-Tyrosine in the mid-afternoon on an empty stomach + 50 mg B6 (P-5-P form) With dinner: A pharmaceutical-grade multivitamin, a Co-Enzyme B Complex vitamin, 1000 mg Vitamin C 100 mg 5-HTP before bed + 50 mg B6 (P-5-P form) The 5-HTP (you can substitute this with L-Tryptophan if you want) increases serotonin and helps me sleep. The L-Tyrosine increases dopamine and norepinephrine and gives me mental focus and energy and physical energy. I think I may have felt like a zombie before on the SSRI's because they were only increasing one of the neurotransmitters in the brain that regulates mood (serotonin), but that I was still deficient in dopamine and norepinephrine. I feel so much better right now than I ever did on SSRI's, and I feel that's the reason. Also, whenever you increase one neurotransmitter like serotonin alone, this will result in a depletion of the others like dopamine and norepinephrine. So it's important to take both 5-HTP/L-Tryptophan and also L-Tyrosine, so they are all being increased at once. The B6 (important that this is the P-5-P form) helps transform the L-Tyrosine and 5-HTP so your body can actually use them. The Co-Enzyme B Complex I take is a really good one and actually has this correct form of B6 in it already, so I may cut down on the extra P-5-P I'm taking throughout the day. The pharmaceutical-grade multivitamin and Vitamin C are giving me more energy throughout the day. I hope this helps someone out there.
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