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james555

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About james555

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  • Birthday 01/01/1972

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    U.S.
  • Interests
    Math, Music, Reading

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  1. Hello! I apologize! I understand very well what you all are going through and feel like I should help and give any good info that might help you ASAP. So sorry! I need to change my email address on here so I get notifications of replies, will try that after I post this. @SSRI I have no experience with Agomelatine. Sorry! My post was way back in February so lots has happened and I've learned more about my depression and what helps and what doesn't. In my opinion, forget those dopamine agonist. If you have treatment resistance depression w/ anhedonia (I can't speak for other types) you need a CNS stimulant and maybe take something like Wellbutrin along with it. But the CNS stimulant is key. There are a lot of bullshit articles on how stimulants are *bad*, mostly in the media. But, taken as prescribed, they are safer and 10x's more effective for people with TRD. If you feel as like it's more of a dopamine problem, then a CNS stimulant is probably as good as you get. Make sure you take the XR type though. Those work like any other add-on or AD like Abilify, etc... The IR Immediate Release type isn't consistent enough to fully do the job IMO. In my case, I am 100% sure it's low dopamine that's cause my TRD/anhedonia as well as some other symptoms like severe concentration issues and loss of all emotions. If those symptoms sound close to what you are experiencing you need to find a good psych that will listen to you and prescribe what works for you. That being said read this article, it's a decent article and has some good points: https://mentalhealthdaily.com/2014/03/13/taking-adderall-for-treatment-resistant-depression/ The article does makes a good point of how "not everyone should be on a stimulant for depression." so there are cases where it's not going to work. Nothing is perfect. But your odds are better with one if you have TRD w/ low dopamine/ahedonia. I know b/c I have suffered from it for 8+ years with hardly any help. It's not a coincidence that I just starting feeling well again almost as soon as I was prescribed one. Just my opinion, but I do not think the type of CNS stimulant matters, as long as it's works similarly, so I wouldn't get hung up on finding the right stimulant. Finding the right dosage is important though so it'll be trail and error. Watch out for caffeine and drink very little, it will cause it not to work well...just my experience.... I wouldn't recommend Pramipex as I don't know enough about it. But if you are looking for a med that will help with your dopamine issues / ahedonia then again, a stimulant is as good as it gets. It'll get you well in my opinion. It's eliminated my concentration issues, anhedonia and my loss of emotion within a a few weeks of finding the right dosage. Even at low doses I saw an improvement. Hope that helps and you get well soon. Took me 8 years until a pysch decided to prescribe this type of med for me. I should have been sooner but happy I found something. For anhedonia, it's the only answer IMO. I stress my opinion. But two things or it won't work...take as prescribed (that's very important, never take more than prescribed) and be patient and find the highest dose that doesn't cause side effects. Hope this helps!
  2. Reading helps, it's the main thing that has helped me as far as natural things. I am hesitant to say any type of reading though. I have exclusively read mostly math textbooks (it doesn't matter what level it is) and then do some problems after I'm done. Recently, I switch over CAD drawing exercises using AutoCAD. It could be the problem solving combined with reading, I'm really not sure.....or, it could be a simple as reading a book so definitely try it. And it's very important that it's a long reading session as well, short times have never really helped me. I spend hours reading doing problems now. Of course, when I was really sick, forget it, it never would have happen due to the anhedonia. That's the death of every bit of your interest...it doesn't matter how "strong" an individual your are, it's the death of an individual too. Reading can help though!
  3. Stay away from it, as far as you can. You will end up spending your time on social media and not working on whatever it is (meds/emotions/etc) you need to be working on. And it's mostly all negative as well, imo. That being said, there are good parts of the internet like this forum. It's always nice to be able to have a place at anytime to share your thoughts, you can't do that any place else. Plus, you get to see/hear all of the other people that are going through hell as well, makes you realize you are not alone.
  4. Hi all! I will have to take the time to read through the various posts when I have time (currently busy with college courses). I remember when the Anhedonia forum was first created so glad to see it still going. I had severe anhedonia from around 2012 through 2016. I remember I told my psych that I felt like it I had reached an end, as far as getting any worse around the end of 2016. Then, from 2017-2019 is has slowly been fading. Unless you have a really good psychiatrist (like I presently have) I think it's something that is not easily fixed with medicine. There are 3 meds have shown to help me, from least to greatest of help: Abilify, Modafinil and stimulants. The issue with stimulants is that most doctors will not prescribe them unless you've been suffering from it for many years and then they still might not. They've help me better than anything else. Note, I found at low doses to be effective, only if it's a light stimulant effect. At higher doses and stronger stimulant effect, it seems to make matters worse, so the dosage is sort of an art, you have to play with it......That and time is the only thing that has seems **** the anhedonia. It's a horrible symptom of depression, that you all are suffering from so I definitely hope you all get some relief soon. At this point, my interest level has slowly started coming back. I spend sometime hours in my studies where that would have been impossible just a year or so ago. One thing though, and it's just my opinion but I think I'm right about this. The anhedonia will not won't last forever. It might be almost a decade lost like in my case (or god forbid longer), but it will eventually start to fade and go away. It just takes a long time for many. But again, those 3 meds all helped me so if you take meds, definitely give them all a try and play with the dosage as much possible before moving on. Hopefully this info helps somebody!
  5. Hi BB33! Glad to see you are trying something to help with your depression. I currently take 200mg of Bupropion immediate release. Honestly, I would at least wait a good 4 more weeks to see if you feel differently. One reason I say this is that I always experienced "startup" effects form the Bupropion at 300mg. But these "start up" effects fade away from me. Example of effects for me were increased libido and energy. These usually last about 1-2 weeks for me, then go away. So be aware of that is all I am saying, not that that will happen. And also, it might happen and you stay feeling energized all day, everyday. I hope so! I would add, t hat I have had treatment resistance depression since 2011 (but thankfully I'm responding to a combination of meds at the moment) so I might not be a good example of the average user taking anti-depressant, many benefit from it. But if you don't respond, realize it's perfectly normal and you need to try something else. Let's hope you respond to it though! I wish you good luck, Bupropion has literally no side-effects for me so I think of it as one of the good AD's. 🙂
  6. Yes, I agree with Lynn1954. Give that 20mg a lot more time before you go into 'panic mode'. Also, and this comes from experience of taking meds for almost 10 years. For some, like me, there's more than one med that will work for you. So don't think, that if for some reason the Lexapro doesn't work for you, there isn't a replacement because there is for many. Hopefully you'll get some relief over the next 7-10 days!
  7. Don't worry, you'll lose the weight over time. I gained 40 pounds over a 5 year period taking various meds (including Pristiq).When I came off my meds for a few months at a time I'd eventually start losing some weight. Of course, I limited my calories and walked some everyday just to make up for what I went over. Personally, I think your body is just being a little stubborn and it's taking some time. But don't worry, if you stick to a plan and don't over eat every meal you'll start to lose again. In fact, I've losed 20 pounds over the last 7 months by limiting my calories and switching meds. Effexor actually is helping me lose weight as it is decreasing my appetite I've noticed, I've lose 5 pounds over the last 2 week...crazy...don't worry though, give it some more time.
  8. Hi again. :) Most of my initial side-effects have gone away and Effexor is working pretty well for me. At 100mg I feel like I need just a little more and at 200mg it's a tad too much and makes me tired during the day. 150mg would be probably perfect. Only issues is 1) I have them in 100mg tabs and 2) Where I go and see a psych there is no way I can get in to get him to prescribe me 75mg dosages. It must be a medical emergency and this isn't one. So I was wondering if anyone had taken their dosages "unevenly". For example, might nightime dosage wouldn't change, I would take 100mg at night but my morning dosage would be only 50mg. This way I know it would cut out all of the tiredness. The other option is take 50mg at night and 50mg during the day. And I can do that, but would rather take 150mg if possibly. So, anyone else do something similar like this or do you all take your dosages evening throughout the day/night? If not, do you think there's anything that I should be concerned with, as far as taking it at different dosages over a 24 hour period? Thanks!
  9. Yeah, the hot flashes are a pain, no doubt about that. I could imagine being in a meeting and sweating like that..lol...people would wonder what's wrong with him. :D ......I decided to taper down to 100mg a day, as opposed to 200mg, and most of the side-effects went away. Of course, some of that is probably just with time as well (I think I've been on it almost 2 weeks). Regardless, my concentration issues are helped tremendously so I'll stay here until I feel like I need to increase the dosage. It's not 100% but it's like 85% back to normal though. It's so nice to be able to read and take in information again. Unless my concentration issues come back this is a good med for me. Only lingering side-effect is lowered blood pressure (I think I dropped 10-15 points on my top number). But, I'm not below 90 so I"m not too concerned about it. I think part of the lower BP is that it must be relaxing my brain and I think that's what was needed for my concentration issues as well...just a guess but makes sense to me. So far, I really like Effexor. I wish I would have stuck w/ it a few years back but I didn't know how to deal w/ side-effects yet...comes with experience I guess. FWIW, I'll probably be on this for life.
  10. Yes, I hope you get stabilized soon OvercomerInOklahoma. Anger is one of my symptoms as well..extreme irritability and anger so I can relate somewhat. For me, the meds mostly just stabilize my mood and not much else. But that's good enough for me. The good thing with this particular med (Venlaflaxine) is it's also helping my ability to focus on tasks. It's some neurological issue w/ my mood disorder where my eyes bounce all over the page so that I'm not able to follow the letters, very bizzare symptom (haven't been able to read for 5 years). So hopefully I can fix this low blood pressure side-effect, stabilize my mood and start taking in information again...and hopefully that'll lead to increased interests...sort of like a domino effect. But yes, I hope Effexor will stabilize you. I hate we all suffer from these mood disorders, it makes life tougher.
  11. Well, just checked my blood pressure it's really low not high. Way lower than usual (I'm usually around 120/70) so it's the meds that doing it. Weird thing as I don't see much about Venlflaxine and low pressure except here: https://www.nami.org/Learn-More/Treatment/Mental-Health-Medications/Venlafaxine-(Effexor). I'm like averaging 100/70 now. The top number is low. And that will cause the fatigue and dizziness I'm experiencing as well. I'll have to do some more search on this and look for ways to increase my blood pressure now.
  12. You mean that could be the reason I'm feeling tired? My BP? That's actually something I hadn't thought of. I'll have to check after my next dosage and see if that's it. I was thinking about halving the dosage and see if that helped but I might check my BP first, then try that. Not 100% I want to play with the dosage yet though. Thanks ladysmurf
  13. Yeah, your body chemistry must be adjusting to effexor differently as I felt initial side-effects after the *first* dosage (nausea/dizziness/teeth grinding). I may be very sensitive the pysch meds, that's my guess. One of my past pychs mentioned that I might be. I'm on 200mg. From my experience, adjusting dosages rarely gets rid of side-effects for me. Either they go away gradually or I'm stuck with them. Good news is that most of the initial symptoms I had (jelly legs/arms, nausea, hot flashes, dilated pupils) are pretty much non-existent. I still am having some hot flashes but not as bad. Except one, fatigue/tiredness, is still present. :( Unfortunately, that's the one I can't live with but I need to give it more time. I've only been on this 8 days. The fatigue is about the same as it was in the beginning so I'm hoping it lets up soon! The Effexor is helping with my concentration issues so I hope the side-effect goes away. I'll give it 2 more weeks and then I'll start to worry.
  14. Yeah, I've heard the withdrawals were pretty bad. I've noticed that the Venlaflaxine is helping with my severe concentration issues so it's worth it to give it a shot. The start-up side-effects are pretty crappy. I'm on day 7 though and it's not as near as bad as day 3 or 4 so I'm hoping all of it goes away. Jelly arms/legs and tiredness isn't as bad today so I'm hoping that goes away pretty soon as I won't put up with that as a permanent side-effect, I have to be able to function w/ normal energy. Jelly arms/legs, fatigue, dilated pupils and hot flashes are my main symptoms. All of them seem to be improving a bit today so I hope this is the beginning of the end. Maybe another week? Plenty of side-effects with this med but if it can help with my severe concentration issues it's worth it, it's tough to function w/ these concentration problems, I can't take in any information this way. Let's hope Effexor does the job.
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