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Augmenting Lexapro & Lamictal


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#1 justaskin

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Posted 22 July 2012 - 07:06 AM

Hello,

I've been on Lexapro 40mg and Lamictal 200mg for who knows how long. It's been doing the trick, and by far is the best combination I've ever used (after trying a LOT of other medications).

However, I am afraid it's either losing it's potency (i've been taking it for some 8 years; perhaps I have developed a tolerance to it? If anyone knows of such a condition i'd love to hear more).

I was wondering if anyone here has experience with a similar situation, and if you have any advice as to adding an additional drug, or perhaps replacing one of them (to be honest, I don't think I'll switch the lexapro; I trust it too much).

I think I just have a general feeling of dysthymia -- although I think all mental disorders, especially depression, are pretty similar and "dividing" them arbitrary by their length / having or not having add'l thoughts / having them combined with other mental disorders doesn't mean much, I want advice as to what you suggest I do.

Thanks!


#2 MaddieLouise

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Posted 22 July 2012 - 11:17 PM

Hi justaskin and welcome to the DF!

Because I'm not a medical professional, it's hard to say definitively what is causing the feeling that the drug combination is not as effective as it once seemed to be. I would definitely make an appt. with your Dr. and explain these new feelings and find out what he/she thinks. Many people have described the feeling as if their meds. are no longer as effective or are wearing out, etc. with any number of medications and posted on these boards. Usually, after visiting with their MDs, sometimes they increase dosages or sometimes they change medications altogether. However, I don't think we become "immune" to our ADs. An article I recently read stated that it isn't really known yet what causes this, but here were some ideas: depression can worsen over time, and something situationally could be triggering you to feel more depressed, so you feel as if the drugs aren't working.

The final suggestion was to see your Dr. to determine what he or she thinks the best course of action is.

Sincerely,

MaddieLouise

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