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Wellbutrin And Effexor Together? So Many Questions...

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#1 K8tc


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Posted 31 December 2011 - 08:42 PM

Hi, I'm new to the forum. I'm from Australia and the use of Effexor and Welburtin (marketed at Zyban in Australia) is not common. In Australia, Wellbutrin is only approved for use as a smoking cessation drug, but many psychiatrists will prescribe it "off lable" as an AD. Because of this, information on it's adjunctive use with Effexor is almost non-existent. I have quite a few questions and I'm hoping someone on here can help me.


#2 solarflare


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Posted 01 January 2012 - 12:34 AM

I take 300mg of Welbutrin slow release and 50grams Luvox, just another SSRI. I havent been on the combination for long, maybe 4 to 5 weeks. They seem too help some, its hard to put a measure on it. I do seem a bit less anxious.

I was on the two separately, first Luvox then switched to Welbutrin. They have different effects. Welbutrin seemed to give me more energy and a bit more focus but didnt help the agitation..LOL The Luvox helps there I think. I am sorry about the horrible side effects for you. Good luck in searching for alternatives.

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#3 Sare


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Posted 01 January 2012 - 05:43 AM

Hi K8tc,

First of all, I just want to say that I'm sorry about all of the horrible side effects you have been experiencing over the years while taking Effexor. I really hope that the change in antidepressants from Effexor to Zyban will be successful for you. Unfortunately, I can't help in answering all of your questions, but hopefully someone on the forum will have experience of taking Effexor and Zyban together. I did want to let you know though that I am also in Australia, and at one point, I took Zyban (300mg) in combination with Cymbalta (90mg) for a period of about six months without any issues. So I guess I wanted to let you know that I was able to combine Zyban with a SNRI.

The other thing that you could consider which is used quite frequently by psychiatrist's to help ease patient's withdrawal symptoms when they are discontinuing from SNRI's such as Effexor and Cymbalta, is to temporarily take a low dose of Lovan (fluoxetine) for a short period as you come off the SNRI - with Lovan's long half life - it seems to help. This was what I had to do to get off Cymbalta because the withdrawal symptoms were really terrible.

Anyway, good luck with it all, and hopefully someone on the forum will be able to answer your specific questions,

Sare :-)

#4 dude333


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Posted 15 January 2012 - 06:01 AM

I've been on effexor for over 4 years in addition to at least 1 year of Wellbutrin. I'm also on Abilify. The Effexor is successful in taking care of my anxiety, and the Welbutrin helps on my lack of energy and mood a little. I take 225 mg of Effexor after dinner, and 3 pills of 100 mg Welbutrin spread throughout the day. Any more Welbutrin than this causes my heart to race after taking my Effexor. But the level I'm at doesn't have any side effects due to the combination of the two. I haven't noticed any side effects from Welbutrin, and some of the side effects from Effexor went away at least partly with the Welbutrin. I still get some Effexor side effects, but that's it.

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