TL;DR (short version) at the bottom.
About 4-5 weeks ago I started taking anti-depressants. First Prozac but it didn't work well with me and I had to switch. Then I switched to Celexa and it worked much better and with less side effects. My depression was receeding and I was starting to be able to function better again. However, I suffered some side effects from Celexa that were not good. I was constantly yawning and tired. And I would wake up in the morning feeling absolutely miserable (physically and mentally). As the day went on I felt better but the next morning it was the same. It also made it a little hard to stay asleep but I could manage.
Enter Wellbutrin XL. My therapist recommended Wellbutrin because it would give me energy to offset the drowsiness and it would improve the terrible feeling I had waking up each morning. So the first day I took the recommended 300mg. And I did not notice a difference. The 2nd day I felt some energy in me and a little shakiness in my body. It took me 2 hours laying in bed before I slept for 4 hours only to lay in bed another 2 hours trying to go back to sleep. By the 3rd day I was trembling uncontrollably and I felt so wired. My mind would not stop racing with thoughts and I was super impatient and irritable. It felt like I was exhausted from the lack of sleep and I just wanted to knock out but something was keeping me up and refusing to let me become calm. It was like torture where they would keep a POW awake from days or weeks by force. So that night I realy wanted to try and get some sleep. I just wanted to sleep for 10 or 12 hours. I decided maybe self-medicating would calm me down and let me get some sleep. Boy was I wrong. I had all the effects of being high and the pain and irritability of being sleep deprived but I was wide away. So that night I went to bed at 5 but could not sleep as my mind would not stop racing from one thought to another. Finally around 7 or so I feel asleep only to take 2 or 3 hours later.
So day 4 i decided I needed to get this out of my system. I have to have some sleep. I stopped cold-turkey after just 3 days. I still felt the effects but similar to day 2 where it was there but more managable. I got similar sleep to day 2 as well with about 4 hours of sleep. So now here I am on day 5, 2nd day off Wellbutrin cold-turkey. I'm going to try and stay awake all day together and not take rests or naps. Maybe I can tire myself out enough and the Wellbutrin will be less enough that I can finally get a decent nights rest again.
And the topic question... After 3 days of Wellbutrin XL 300mg and three nights of inability to sleep more than 3-4 hours, how much longer would you presume it to take before the effects of Wellbutrin leaves my system enough to allow me to get a decent nights rest?
note: I am also taking Celexa 20mg and I am on my 2nd day off Wellbutrin cold-turkey. So it is now day 5.
Edited by Sheepwoman, 26 June 2011 - 07:55 PM.