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JustDawleyGirl

Does Wellbutrin Cancel Out Effects From Other Meds?

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Posted

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I had surgery several months ago and just recently reinjured the surgical site. I am back on Vicodin for pain but I am getting no relief whatsoever (this is also intertwined with Motrin 600 mgs, on an alternating schedule). When I had my surgery initially, the Vicodin did the trick alone and Motrin was mainly for swelling. However, since then, my P-doc put me on 150mgs of WB XL, and upped my dosage about a week and a half ago to 300mgs of WB XL (same drug; higher dosage). I'm wondering if the WB is somehow cancelling out the effect of my pain medication though my doc didn't seem to think that would be the case. Additionally, I was recently prescribed 1mg of Xanax for my awful panic attacks and anxiety that has been worsening lately and it literally does nothing for me so I haven't been taking it. What's the point of putting something like that into your body if you get no relief and experience the anxiety and attack anyway?

I feel like my WB, while helping significantly with my depression, is presenting a downside with my other dominant issues and meds, and I was wondering if anyone else has experienced this? I have an appointment with my p-doc in two weeks but I don't know if I can wait until then, though my problem is not considered an "emergency" in my doc's office's terms to justify an earlier appointment.

Any advice from similar experiences or help is much appreciated. Thanks, DawleyGirl

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Posted

Welcome to the forums! :welcomeani:

Those of us who take several kinds of medications, face a real balancing act, don't we?

I can't offer any expert advice but, I can relate my own experience. Whenever, I've needed a strong pain medication (like Vicodin) it's been after a surgery when, I would be flat on my back and not taking any anti-depressants. Usually those strong pain meds (the opiates) make me so dizzy and sleepy I can barely function, anyway.

On an average day, I take a small dose of Xanax every night to help with anxiety and sleep. I've been blessed that I seldom need more but, every now and then, I get a panic attack and need extra. I take a Wellbutrin & Paxil combo, every morning. I sometimes wonder, if the timing of different medications makes the difference in the effectiveness. I haven't heard any stories of Wellbutrin blocking another med but, your doctor would know best.

Let us know how things go for you!

Take care,

Aerial

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Posted

When I was taking wellbutrin in higher doses I did notice that it seemed to reduce the effectiveness of the adderall I was taking.. In fact it seemed to dull the sensation to any mind-altering substance I used.

I am not sure about the pain factor but like I say I can tell you that it seemed to blunt any substance I took effecting the brain.

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Posted

I took Wellbutrin in combo with Vicodin with positive response for both. However, we all react/respond to meds differently. The other possibility is that the Vicodin no longer has the effect on your pain as it once did. This is something you need to discuss with your medical doc.

Sheepwoman

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Posted

I see more often than not that people's p-doc's are prescribing combinations of SSRI's or antidepressants like Wellbutrin with Paxil or Adderal (I'm not sure what that even is)...what is the benefit of a doc creating a customized "cocktail" of depression-related medications over just prescribing one over another? I really think I need to switch docs to someone who knows better what they are doing. My p-doc now is a geriatric internist (I'm 38 as of today so hopefully this is not a specialty doc that I need to be seeing yet, anyway). I sort of ended up with him as part of being shuffled around a few years back within a private practice from the primary doc I used to see normally. He's gentle and kind but I don't know that he necessarily has the experience and knowledge of these kinds of medicines and listening to me about what's really going on to help me fight it.

I'm also so afraid to ask certain questions as to not want to offend him or insult his intelligence if I'm making suggestions (as if he wasn't capable of coming up with them on his own) so I usually just sit there quietly and cry hoping he will help come up with suggestions or alternatives to things that aren't working for me. This only contributes to my own anxiety and stress because more often than not I end up leaving my doc's office more stressed and feeling like I'm no better off on the right road than relieved that I saw him and I am. Does anyone else ever feel this way or is it just me needing to grow a backbone and either be more assertive or find a doc more suited to what I'm going through in my life these last few years?

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