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Taking Cipralex And Trazodone At The Same Time


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#1 happygranny

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Posted 07 July 2009 - 05:50 PM

Hello, I am new here, this is my first post so hopefully I am doing this correctly.
I have been taking Trazodone for over 5 years now, starting at 50 mgs and now up to 100 mgs for sleep. I was Dxd with FMS and CFS/ME after 3 years for searching for answers, in 2003. I was then tested positive for Lyme disease in 2005 and been on and off ABX until February this year when I stopped because I didn't think I was getting much better anymore and in fact was getting worse.

I do suffer depression, though no anxiety attacks, mostly not able to feel much emotion anymore. I do feel contented, just no emotional highs and lows.

My Doctor Rxd Cymbalta first and after 3 or 4 days I was very paranoid and having strange thoughts so I stopped. Now I am about to try Cipralex but when I bought the Rx into the pharmacy I was told there could be a problem because of an interaction between Trazodone and Cipralex. They checked with my doctor and he said I could go ahead with it because of the doses (I guess?).

I take 100 mgs of TRazodone at bedtime and supposed to take 10 mgs of Cipralex but hesitate because of the interaction possibility.

Has anyone had experience with this?
Thanks,
happygranny

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#2 larkinthemorning

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Posted 08 July 2009 - 12:57 PM

Hi, and welcome to the forums! I have been on trazodone and celexa for two years (minus 6 months when I stopped the celexa but was still on the trazodone) and I've been fine, no interactions. I am taking 200 mg of trazodone at night and 20 mg of celexa in the morning. Did the pharmacist say what the possible interaction could be? Just curious.

#3 happygranny

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Posted 08 July 2009 - 02:54 PM

Hello Larkinthemorning, thankyou for your response, I appreciate that. Celexa and Ciprolax are fairly similar in make-up from what I have read, so that is good news.

T he warning was about Serotonin accumulation that could cause muscle spasms. I did some searching about it online and am afraid I don't understand a lot of what I read, but it did say something about : Selective Serotonin Reuptake Inhibitors with Tricyclic Compounds (Trazodone) being a Level 3 in Severity being Moderate Interaction and directions are to assess the risk to patient and take action as needed. My doctor figured there was no problem, but I still hesitate to start it.

also I am feeling quite sick right now and I think it is a reaction to the Oxycontin I am taking for Peripheral Neuropathic pain.

Thanks again,

Happygranny

Hi, and welcome to the forums! I have been on trazodone and celexa for two years (minus 6 months when I stopped the celexa but was still on the trazodone) and I've been fine, no interactions. I am taking 200 mg of trazodone at night and 20 mg of celexa in the morning. Did the pharmacist say what the possible interaction could be? Just curious.






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