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Medication Suddenly Stopped Working


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15 replies to this topic

#1 mik71

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Posted 24 October 2008 - 01:08 PM

Hi all,

I've been taking 150mg of Effexor along with 30 mg of Zispin for the past three months or so. It was doing me the world of good first but I've found myself feeling depressed and anxious again for the past week or so. In fact, the past three days have been fairly horrible because I can't sleep and all my feelings of panic have come back. I have a horrible tension headache and my chest feels like it's closing in, along with a general feeling of doom.

Just wondering if anyone had temporary setbacks on this stuff?

Thanks for listening :hearts:

#2 lm71

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Posted 24 October 2008 - 02:32 PM

Hi all,

I've been taking 150mg of Effexor along with 30 mg of Zispin for the past three months or so. It was doing me the world of good first but I've found myself feeling depressed and anxious again for the past week or so. In fact, the past three days have been fairly horrible because I can't sleep and all my feelings of panic have come back. I have a horrible tension headache and my chest feels like it's closing in, along with a general feeling of doom.

Just wondering if anyone had temporary setbacks on this stuff?

Thanks for listening :hearts:


Mik71
Yes i had the exact same thing happen to me on effexor xr this past summer. Just one day out of the blue in the grocery store I started having anxiety and did not sleep at all that night and spiraled down from there. I felt horrible panic, dizzy, weepy, lack of appetite, depression. So I think that this can happen where they just stop working. How long have you been on the effexor?

#3 mik71

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Posted 24 October 2008 - 02:46 PM

Hi all,

I've been taking 150mg of Effexor along with 30 mg of Zispin for the past three months or so. It was doing me the world of good first but I've found myself feeling depressed and anxious again for the past week or so. In fact, the past three days have been fairly horrible because I can't sleep and all my feelings of panic have come back. I have a horrible tension headache and my chest feels like it's closing in, along with a general feeling of doom.

Just wondering if anyone had temporary setbacks on this stuff?

Thanks for listening :hearts:


Mik71
Yes i had the exact same thing happen to me on effexor xr this past summer. Just one day out of the blue in the grocery store I started having anxiety and did not sleep at all that night and spiraled down from there. I felt horrible panic, dizzy, weepy, lack of appetite, depression. So I think that this can happen where they just stop working. How long have you been on the effexor?


Hi,

I've been on them roughly about three/four months. I started off on 75mg, then went up 150mg, then 150mg with 30mg Zispin to help me sleep (they don't help much).

I just feel as if they've stopped working all of a sudden, like the way that you explained. It's very strange because I seemed to be doing quite well on them.

#4 lm71

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Posted 24 October 2008 - 02:48 PM

Hi all,

I've been taking 150mg of Effexor along with 30 mg of Zispin for the past three months or so. It was doing me the world of good first but I've found myself feeling depressed and anxious again for the past week or so. In fact, the past three days have been fairly horrible because I can't sleep and all my feelings of panic have come back. I have a horrible tension headache and my chest feels like it's closing in, along with a general feeling of doom.

Just wondering if anyone had temporary setbacks on this stuff?

Thanks for listening :hearts:


Mik71
Yes i had the exact same thing happen to me on effexor xr this past summer. Just one day out of the blue in the grocery store I started having anxiety and did not sleep at all that night and spiraled down from there. I felt horrible panic, dizzy, weepy, lack of appetite, depression. So I think that this can happen where they just stop working. How long have you been on the effexor?


Hi,

I've been on them roughly about three/four months. I started off on 75mg, then went up 150mg, then 150mg with 30mg Zispin to help me sleep (they don't help much).

I just feel as if they've stopped working all of a sudden, like the way that you explained. It's very strange because I seemed to be doing quite well on them.



Maybe you should call your doc he/she may have some insight. But it does sound like the effexor has stopped working or maybe you need an increase.

#5 mik71

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Posted 24 October 2008 - 03:06 PM

Hi all,

I've been taking 150mg of Effexor along with 30 mg of Zispin for the past three months or so. It was doing me the world of good first but I've found myself feeling depressed and anxious again for the past week or so. In fact, the past three days have been fairly horrible because I can't sleep and all my feelings of panic have come back. I have a horrible tension headache and my chest feels like it's closing in, along with a general feeling of doom.

Just wondering if anyone had temporary setbacks on this stuff?

Thanks for listening :hearts:


Mik71
Yes i had the exact same thing happen to me on effexor xr this past summer. Just one day out of the blue in the grocery store I started having anxiety and did not sleep at all that night and spiraled down from there. I felt horrible panic, dizzy, weepy, lack of appetite, depression. So I think that this can happen where they just stop working. How long have you been on the effexor?


Hi,

I've been on them roughly about three/four months. I started off on 75mg, then went up 150mg, then 150mg with 30mg Zispin to help me sleep (they don't help much).

I just feel as if they've stopped working all of a sudden, like the way that you explained. It's very strange because I seemed to be doing quite well on them.



Maybe you should call your doc he/she may have some insight. But it does sound like the effexor has stopped working or maybe you need an increase.


Yeah, I think so. What about your situation? Did you up your dosage?

#6 Guest_Giz_*

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Posted 24 October 2008 - 03:07 PM

Just a question-when you say they were doing you the world of good at first-just how good were you?

Only reason Im asking is when I started effexor they made me kinda manic for a bit. Then they eased off. and seemed to be ok, then they stopped working..They upped the dose, nothing..

Now firstly, Ive found on here that the reactions I had to effexor, & before that, Cipramil, could indicate that I am in fact bi polar type II, along with some other indicators..

Personally, I came off effexor in february. Since then I have been taking a high dose natural source multivitamin & eating whole foods & organic where possible, and lots more veg. I dont drink caffeinated drinks, and Im cutting my refined sugar intake..
I feel better than I did on either set of medication, so I am inclined to believe that my problem may have had its base in nutrition.

There is a post I put up on here called Nutrition & Mental Health, I suggest you search for it, take the questionnaires and see which ones you score highest in. Then follow the advice. If you are taking the Effexor or any other medication then dont use 5Htp, Sam E, St Johns Wort, or Rhodiola-as they could interfere with each other. Ginseng interferes with one of the other types of Anti depressant-so be careful about these things.. But vitamins & minerals are fine.
Also-if buying a multivitamin be careful about which ones you buy, look at the ingredients and make sure they are natural source vitamins. Synthetic ones are not as good.

Im no suggesting you quit the meds-just saying try this as well, and see if you notice a difference, if you do then your problem may be nutritional. If it is, then you might not need the meds. One way or the other youll feel better. And then perhaps youll get involved in in the cause to stop the proposed restrictions on these beneficial nutrients by Codex(pm me if you want more information on that)

Good luck!!

Edited by Giz, 24 October 2008 - 03:10 PM.


#7 mik71

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Posted 24 October 2008 - 06:34 PM

Just a question-when you say they were doing you the world of good at first-just how good were you?

Only reason Im asking is when I started effexor they made me kinda manic for a bit. Then they eased off. and seemed to be ok, then they stopped working..They upped the dose, nothing..

Now firstly, Ive found on here that the reactions I had to effexor, & before that, Cipramil, could indicate that I am in fact bi polar type II, along with some other indicators..

Personally, I came off effexor in february. Since then I have been taking a high dose natural source multivitamin & eating whole foods & organic where possible, and lots more veg. I dont drink caffeinated drinks, and Im cutting my refined sugar intake..
I feel better than I did on either set of medication, so I am inclined to believe that my problem may have had its base in nutrition.

There is a post I put up on here called Nutrition & Mental Health, I suggest you search for it, take the questionnaires and see which ones you score highest in. Then follow the advice. If you are taking the Effexor or any other medication then dont use 5Htp, Sam E, St Johns Wort, or Rhodiola-as they could interfere with each other. Ginseng interferes with one of the other types of Anti depressant-so be careful about these things.. But vitamins & minerals are fine.
Also-if buying a multivitamin be careful about which ones you buy, look at the ingredients and make sure they are natural source vitamins. Synthetic ones are not as good.

Im no suggesting you quit the meds-just saying try this as well, and see if you notice a difference, if you do then your problem may be nutritional. If it is, then you might not need the meds. One way or the other youll feel better. And then perhaps youll get involved in in the cause to stop the proposed restrictions on these beneficial nutrients by Codex(pm me if you want more information on that)

Good luck!!


Hi, thanks for your response.

Well, to be honest, I eat very well and exercise every day so I don't think that's the problem. Having said that, I will take a look for your questionaire and see what the results are.

As regards your question about how good I was feeling intially, I'd say that I just felt a bit more relaxed but still quite melancholic. I also noticed today that when I felt that I was after dipping into a low point I suddenly went a bit manic for a while, and then dipped again

#8 mik71

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Posted 04 November 2008 - 08:50 AM

Well, I decided to go cold turkey on this stuff and I'm off it now six days. I had my therapist appointment today and I told him straight up that I wasn't going to take it any more.

First off, going cold turkey isn't for everyone and weaning is probably the more sensible way to do it. Anyway, I've had the brain zaps, a flu/hungover feeling, insomnia and stomach upset. Last night, I didn't sleep at all! Okay, that sounds scary to people I'm sure, but I'm out of work at the moment so I've been able to cope with things at my own pace. If you are going cold turkey, try to do it at a time when maybe you can take a couple of days off work, or during a quiet time. Another thing that made it a little easier for me was the fact that I told some close friends what I was doing, and that I might be out of sorts for a week or so. Whilst I still had to go through the s***ty feelings on my own, it did help knowing that I could ring or sms a friend whenever I felt low.

I suppose what I'm saying is that if you are going to taper off the stuff or go cold turkey, try to make it as comfortable as possible for yourself. That could mean getting a friend or family member over for a cup of coffee, or to watch a movie or whatever. Even if that's not an option, you could post your progress on here, even if it means saying that you want to throw your cat out the window!

I feel as if I'm getting over the worst now after a few unpleasant days, but it just takes time and a degree of optimism.

Anyway, I hope that this post can help anyone who may need it, and to let them know that it can be done.

#9 Guest_Giz_*

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Posted 04 November 2008 - 04:44 PM

How did you get on with the questionnaire?
Just wondering seeing as you decided to come off the meds..
Hope youre feeling better now!!

#10 mik71

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Posted 04 November 2008 - 06:25 PM

How did you get on with the questionnaire?
Just wondering seeing as you decided to come off the meds..
Hope youre feeling better now!!


Hi,

I'm still feeling a little out of sorts, but the lack of sleep isn't helping. I'm hoping to get a reasonable night's kip tonight.

Yeah, I took a look at that questionaire and it's very interesting. Actually, I've been low in B12 occasionally and when I got a shot it gave me a good boost. I can also relate a lot to the histamine imbalance section; that's something I'll be investigating further.

Anyway, Im hoping to feeling much better by the end of the week. I'll keep everyone posted, just for future reference in case anyone else decides to go cold turkey.

#11 Guest_Giz_*

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Posted 04 November 2008 - 07:22 PM

I went cold turkey and Bachs Rescue Remedy helped immensely with the crazy trembling/shaking where I felt like my core was having a fit and breathing was difficult..
I was also receiving an aromatherapy and a hot stone massage each week, and giving myself Reiki..(I was still in college, oh how I miss regular treatments!!)

Hope you feel better soon, someone else mentioned getting colds and stuff, I think that may be partially as your body is run down from the "discontinuation syndrome". Echinacea helps boost respiratory immunity, and tea tree oil is an immuno stimulant. One drop of it and one drop of lavender to boost its effect in a bowl of hot water and inhaled can help you with this..Please only use 1 drop of each-using too much could actually have the opposite effect..(It would be like an overdose)

Best of luck-Valerian Tea can be very helpful if the sleep is evading you.. It wont necessarily put you to sleep(its not that heavy duty), but if you are running on empty it will, and enhance your deep sleep so that your sleep is more beneficial.

Keep us posted! And if I can be of any help, PM me!

#12 mik71

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Posted 12 November 2008 - 07:17 PM

I went cold turkey and Bachs Rescue Remedy helped immensely with the crazy trembling/shaking where I felt like my core was having a fit and breathing was difficult..
I was also receiving an aromatherapy and a hot stone massage each week, and giving myself Reiki..(I was still in college, oh how I miss regular treatments!!)

Hope you feel better soon, someone else mentioned getting colds and stuff, I think that may be partially as your body is run down from the "discontinuation syndrome". Echinacea helps boost respiratory immunity, and tea tree oil is an immuno stimulant. One drop of it and one drop of lavender to boost its effect in a bowl of hot water and inhaled can help you with this..Please only use 1 drop of each-using too much could actually have the opposite effect..(It would be like an overdose)

Best of luck-Valerian Tea can be very helpful if the sleep is evading you.. It wont necessarily put you to sleep(its not that heavy duty), but if you are running on empty it will, and enhance your deep sleep so that your sleep is more beneficial.

Keep us posted! And if I can be of any help, PM me!



Hi,

Well, I'm feeling much better now. I went out at the weekend and socialised as normal, and I've managed to catch up on my sleep. The brain zaps are pretty much gone too. My doctor did give me a few days worth of sleeping tablets and they helped immensely. I'd never taken one before and I wouldn't make a habit of it, but they helped me a lot getting back on track; not being able to sleep just makes things far worse.

One thing that I will say is that my councellor wasn't very understanding in reation to my claim that the effexor was wearing off. My doctor, on the oher hand has been very helpful, and although he wasn't overly happy about me going cold turkey on the Effexor, he was very understanding of why I did.

Anyway, just to let others know that they can kick the Effexor. You will feel bad for a while (probably depending on the dosage and how it's been taken for) but it can be done :hearts:

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Posted 12 November 2008 - 07:39 PM

One thing that I will say is that my councellor wasn't very understanding in reation to my claim that the effexor was wearing off. My doctor, on the oher hand has been very helpful, and although he wasn't overly happy about me going cold turkey on the Effexor, he was very understanding of why I did.


How do you mean? When I told my doc that they had stopped working he went on about upping the dosage etc.. He didnt seem to really believe that they could just stop working.. The thing is, I think they had me quite manic for a while, but mildly manic for a longer period, which is why when that wore off I felt so bad..

It was only when I said to him that I had seen the article about how their effects were deemed "insignificant" and that I was quitting them and had accidentally started cold turkey that he listened.. (He also didnt seem to believe that I had lost my libido-as that only happens to 2% of people on them.. I dont know how he thought the fact that I had less interest in sex than I have in football was normal..I find football boring by the way..)

In reality, I was put on a drug that messed with the way my brain works. I used to trust them implicitly, now Im enraged that nutrition was never even mentioned to me. And that they failed to spot mania..And the more I research into the pharmaceutical industry's stranglehold on psychiatry the more sick it makes me feel that I was duped..

Glad to hear that you are feeling better.. Are you vegetarian/vegan by any chance??

#14 DeeBear

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Posted 12 November 2008 - 07:50 PM

Hi Mik71,

Yes, you can come off meds, and I definitely understand how frustrating it is when counselors don't listen.

But, quitting cold turkey is not a good idea, unless your doc determines that there's a good enough reason for it! I just wanted to say to anyone contemplating quitting cold turkey that it can be very difficult - as I know all too well. And please, talk to your doc, hopefully they'll understand as Mik71's did. I know it's a tremendous help when they do, but they can only deal with what you tell them!

Take care,
Dewayne
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#15 mik71

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Posted 17 November 2008 - 02:39 PM

One thing that I will say is that my councellor wasn't very understanding in reation to my claim that the effexor was wearing off. My doctor, on the oher hand has been very helpful, and although he wasn't overly happy about me going cold turkey on the Effexor, he was very understanding of why I did.


How do you mean? When I told my doc that they had stopped working he went on about upping the dosage etc.. He didnt seem to really believe that they could just stop working.. The thing is, I think they had me quite manic for a while, but mildly manic for a longer period, which is why when that wore off I felt so bad..

It was only when I said to him that I had seen the article about how their effects were deemed "insignificant" and that I was quitting them and had accidentally started cold turkey that he listened.. (He also didnt seem to believe that I had lost my libido-as that only happens to 2% of people on them.. I dont know how he thought the fact that I had less interest in sex than I have in football was normal..I find football boring by the way..)

In reality, I was put on a drug that messed with the way my brain works. I used to trust them implicitly, now Im enraged that nutrition was never even mentioned to me. And that they failed to spot mania..And the more I research into the pharmaceutical industry's stranglehold on psychiatry the more sick it makes me feel that I was duped..

Glad to hear that you are feeling better.. Are you vegetarian/vegan by any chance??


Hi,

No, I'm not a vegetarian. I like meat way too much!! When I told my councellor that the Effexor wasn't working anymore, he said that something else must have happened to make me suddenly feel bad. He asked me if I was drinking too much or taking street drugs. I wasn't so then he maintained that because I'm out of work at the moment that it must have been that! I felt that he was being very simplistic about the entire matter, and completely in denial about the medication not working. I was very disappointed with his attitude, and I honestly have to say that my doctor was far more helpful.

#16 mik71

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Posted 17 November 2008 - 02:45 PM

Hi Mik71,

Yes, you can come off meds, and I definitely understand how frustrating it is when counselors don't listen.

But, quitting cold turkey is not a good idea, unless your doc determines that there's a good enough reason for it! I just wanted to say to anyone contemplating quitting cold turkey that it can be very difficult - as I know all too well. And please, talk to your doc, hopefully they'll understand as Mik71's did. I know it's a tremendous help when they do, but they can only deal with what you tell them!

Take care,
Dewayne


Hi,

Yes, I would like to emphasise again that cold turkey isn't for everyone. People - always talk to your doctor about how your medication is going for you, whether it's good or bad. It's very important to stay in touch with your doctor and keep him/her up to date with how things are going.




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