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tina

Switchng From Cymbalta To Pristiq

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Posted

I have gained TONS of weight on Cymbalta and went to the Doctor today and he gave me samples of Pristiq. Who all has tried this? I will be taking it with Lamitical because of Bipolar? Any advice will be appreciated! I had been cutting back on my cymbalta for the past 2 weeks.

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Seeing that no one has replied to this, I wanted to say that this is the newest ad out there and hope you let us know how it goes for you!!!!

Jackie

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Posted

I have gained TONS of weight on Cymbalta and went to the Doctor today and he gave me samples of Pristiq. Who all has tried this? I will be taking it with Lamitical because of Bipolar? Any advice will be appreciated! I had been cutting back on my cymbalta for the past 2 weeks.

Hi Tina.

This is great! I have been on Lamictal for years and Cymbalta for 4 months. The Cymbalta has caused weight gain of about 15 pounds in a month or so. Never before have I gained weight with any medication, and whats more is I cannot even get the weight off!

My doctor switched me to Pristiq just yesterday. I forget to ask him how to switch, so this morning I simply replaced a 60-mg tablet of Cymbalta with a 50-mg of Pristiq. Hope I'm still alive in a few hours!

The research I read on Pristiq is not very encouraging. Basically, it is a patent extender for Wyeth. The only difference in Pristiq and Effexor seems to be that the 50-mg dose is the actual therapeutic dose. There is no need for titration, so you will find out faster whether it works or not.

Cymbalta worked better than Effexor for my mood and anxiety but weight gain is something that will end up making me more depressed - something I will not live with. It should be interesting to see if the weight comes off. If it does, maybe the joy I get from losing weight will make up for the lack of efficacy from Pristiq.

Keep posting on this one!

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Posted

I recently (2 weeks ago) was switched from Cymbalta to Pristiq. At the same time I was added Wellbutrin (the generic) at 300mg per day. My depression & nerves have been the worst in a long time. But I've heard this can happen with new WB users, so I honestly can't comment on the Pristiq.

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Update: Day 6 on Pristiq.

Wow. This seems to be working great. I have more energy and motivation, decreased appetite, and am no longer taking naps during the day. What a difference from what appeared to be a slowed metabolism from the Cymbalta. As far as my mood, it is about the same as on Cymbalta but if my weight is controlled and my energy stays up, that alone will lift my mood.

Loving it so far.

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Posted

Pristiq is basically a new form of Cymbalta, so be careful!! If you had negative side effects on Cymbalta, you will probably have them on Pristiq as well. The Wellbutrin may mask the negative Pristiq side effects at first, so monitor your feelings and energy level carefully. If you begin to feel tired, lethargic, and/or apathetic, I encourage you to re-evaluate your use of Pristiq. The Pristiq could be making you worse (like Cymbalta does to many people). Pristiq has only been on the market since Feb. 2008, so there is not much public info available yet.

You may only need the Wellbutrin to help you feel better.

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Posted

Pristiq is no way, shape or form related to cymbalta. It is the active metabolite of effexor.

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Posted

Effexor, Cymbalta and Pristiq are all in the same category of anti-depressants: serotonin-norepinephrine reuptake inhibitor (SNRI).

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Posted

I have gained TONS of weight on Cymbalta and went to the Doctor today and he gave me samples of Pristiq. Who all has tried this? I will be taking it with Lamitical because of Bipolar? Any advice will be appreciated! I had been cutting back on my cymbalta for the past 2 weeks.

I am on day 4 of taking Pristiq. I sure hope I dont gain weight. As for my depression, well there is no change but I guess it's too soon to tell. Everything I read on here about medication scares the heck out of me.

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Posted (edited)

I have gained TONS of weight on Cymbalta and went to the Doctor today and he gave me samples of Pristiq. Who all has tried this? I will be taking it with Lamitical because of Bipolar? Any advice will be appreciated! I had been cutting back on my cymbalta for the past 2 weeks.

I am looking into making this switch as well. I have gained weight on Cymbalta which is leaving me feel depressed. Have you noticed a loss of the weight you gained while on Cymbalta after the switch?

Edited by 4mykids

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Posted

I have gained TONS of weight on Cymbalta and went to the Doctor today and he gave me samples of Pristiq. Who all has tried this? I will be taking it with Lamitical because of Bipolar? Any advice will be appreciated! I had been cutting back on my cymbalta for the past 2 weeks.

I am looking into making this switch as well. I have gained weight on Cymbalta which is leaving me feel depressed. Have you noticed a loss of the weight you gained while on Cymbalta after the switch?

Hi 4MK,

I know what you mean about the weight gain on AD. Years back when I was on Paxil I gained about 40 pounds and was horribly depressed. Eventually I decided to stop taking them because of that. I am now on Cymbalta and have been for about 5 weeks now. I am just now getting my appetite back

(I had none when I first started Cymbalta) and if anything I've lost weight. I'm still scared to death that it may still happen on Cymbalta. How long have you been on it? It's crazy how some people gain, others lose. You just never know. I'm just trying to eat smart these days and hoping for the best.

Thanks!

TTysoon :hearts:

Tink

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Posted

Hi Tink,

I've been on Cymbalta for about 3 months now. It's just been in the last month that I've gained the weight and that's what has me terrified. 10 lbs in one month! I'm hoping the Pristiq will level out this weight thing. Other than the weight, I'm happy with the way it was working. I feel good, a little tired, but good.

You are right when you say it affects people differently. Just hang in there.

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Posted

Hi Tink,

I've been on Cymbalta for about 3 months now. It's just been in the last month that I've gained the weight and that's what has me terrified. 10 lbs in one month! I'm hoping the Pristiq will level out this weight thing. Other than the weight, I'm happy with the way it was working. I feel good, a little tired, but good.

You are right when you say it affects people differently. Just hang in there.

Hi again!

What dose are you on? I'm on the 60mg but I think I need an increase. I don't feel much of anything these days. I'm just at an even keel. Not as bad as I was, but not nearly where I want to be. I'm on it for Anxiety, OCD and severe Depression. I'm going to the doctor's next week and hopefully she will be able to help me and adjust the dose. I have a high tolerance to drugs so who knows. I had my Paxil dose increased many times as well.... so who knows. I just want to feel better, and I'm slowly losing hope :hearts:

Thanks again!

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Posted

well after reading your posts i truely dont want to go on cymbalta!! i cant deal with anymore weight gain ! feeling fat and unwanted does nothing for my depression !!! ugh !

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Posted

Hi again!

What dose are you on? I'm on the 60mg but I think I need an increase. I don't feel much of anything these days. I'm just at an even keel. Not as bad as I was, but not nearly where I want to be. I'm on it for Anxiety, OCD and severe Depression. I'm going to the doctor's next week and hopefully she will be able to help me and adjust the dose. I have a high tolerance to drugs so who knows. I had my Paxil dose increased many times as well.... so who knows. I just want to feel better, and I'm slowly losing hope :hearts:

Thanks again!

Hi Tink,

I'm on 60 mg as well. I went back to my doctor after two months to have it increased and apparently the research shows that a higher dose isn't more effective. We waited it out and I am definitely feeling better. I was on 200mg of Zoloft a few years ago. Other than the weight issue, I am feeling much more relaxed, patient and balanced. I wish I could feel this way without taking medicine. The weight thing leaves me feeling too depressed though to continue with this medication, which essentially is counter productive. My pants were tight this morning when I went to put them on and I just started crying. I threw out all my "fat clothes" when I lost the weight because I didn't want going back to that to be an option for me. Don't lose hope though, Tink. Somewhere we'll find the answer we are looking for.

4MK

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Posted

I'm sorry, I'm new here, but I'm a little baffled by all these people saying they gained all this weight. Every forum I've been to seems to have horror stories about gaining weight, yet no stories about people who HAVEN'T gained weight.

Well. I'm on Cymbalta and I actually lost weight. Crazy huh? When I was depressed I couldn't eat. It only makes sense that now that I'm happy, I would gain happy weight. Fortunately for me though, I was never the type to eat emotionally, whether happy or sad, so I didn't gain any weight. Seriously, weight gain is NOT a direct side effect - the increased appetite is.

Just exercise, and stop this whole I'mgoingtogetfat so Imightaswellgetfat mentality and go outside! Take a walk! Walk your dogs! Life is awesome.

Obviously, Cymbalta is working for me.

Let's here it for the people who are actually doing GREAT on ADs!! Speak up! Life is a helluva lot better than when I was depressed, fat or not!

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Posted

I'm switching back to Cymbalta. Pristiq is not working for me. In fact, I feel awful. I am impatient, irritable and the mood swings have my husband unsure whether he should hold me or run. Cymbalta was working for me mood-wise, better than any drug has ever. It was the weight gain and sexual side effects that bothered me most, but if I am smart with my eating and diligent about exercise, maybe I can combat that, at least the weight. Maybe I'll ask for some Viagra for women! Seriously though, Pristiq is not for me: headaches like I've never experienced, I haven't slept properly since I started taking it and when I am sleeping, I'm having really strange and disturbing dreams.

I got pretty sick making the switch to Pristiq-I hope it isn't as bad when I switch back.

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Posted (edited)

Hello All -

I just joined today and this is my first post. I was diagnosed with low levels of seratonin back in 2006. I tried Prozac for 6 months, felt much better, went off it for 3 months, and started to get down again. My doctor switched me to Lexapro. I tried it for 1 year, and as I continued feeling pretty good, I tried going off it. Within another few months I started noticing symptoms again. I've always had trouble sleeping, problems with headaches/migraines, and just didn't feel motivated to do much of anything. My doctor said that 50% of people can go on an SSRI and come off in 6 months and be fine - the same thing goes for the 12 month "2nd trial." Since it was clear that I was worse off without the help of the medication, I began taking Cymbalta in the summer of 2007 and have recently been on 120mg a day. Over the last year I've noticed quite a bit of belly fat accumulating and became concerned about weight gain. I revamped my diet and began eating more small meals a day, lots of chicken/fish/fresh fruits/veggies, and maintained an exercise regimen. I even purchased and started the P90x workout program but had to stop around day 50 because I found out I have two herniated discs in my back (unrelated, unknown cause). I generally drink 1 gallon of water a day and focus on fresh/organic foods and low sugar snacks/meal replacements. I drink a lot of smoothies and add Acai, L-glutamine, and creatine supplments as well as take Tonalin-CLA to boost my metabolism's fat burning.

NONE of all the things I tried made a difference. I was shocked that I couldn't get rid of ANY excess body fat while going through the rigorous P90X workout program. Since I've been hurt, I haven't been able to exercise much, but I have maintained eating healthy and drinking plenty of water (avoiding pop and other sugar filled drinks). I didn't gain much more weight, but it feels/looks like I've lost some muscle weight and continue gaining fat weight in my abdominal area. This frustration has KILLED my self esteem and has made me feel more depressed than usual. I talked to my doctor about my weight/body fat % concerns and he told me I look fine and not to worry about it. I couldn't accept that and started researching to see if Cymbalta may be part of the problem. Over the last year or so I've felt in kind of an indifferent "fog" - not so many highs and lows, just an every day average feeling. I've noticed that since I've been on Cymbalta I have battled sugar cravings at various times of the day, and found myself snacking all the time, even into the night. I'm doing all I can now to keep snack foods out of my house and not eating anything before bed.

After looking into Cymbalta, from what I could find, several other people seem to attribute weight gain (specifically fat) to being on Cymbalta. After seeing so many commercials about adding Abilify to help with symptoms, and now seeing Pristiq commercials, I started looking into switching to Pristiq. I have read a lot of people's testimonies who have made the switch and they have noticed a better overall feeling and even dropped weight in a lot of cases. I called my doctor and requested to switch over from Cymbalta to Pristiq. I know going off of Cymbalta has a withdrawl period, but my doctor explained that switching right to Pristiq would not be a problem and I shouldn't experience any problems. Maybe it's just a psychological thing and/or something new we're all looking for hope in, but I'm going to give Pristiq a try and see how my body and mind respond to it. Lately I've remained in a depressed fog, and being stuck at home because I can't do much of any physical activity has not helped. I just want to enjoy more things in life instead of constantly thinking about the things I'm unhappy about. I should look forward to walking my dog, taking care of my house, taking good care of myself, and so many other things. Here's to hoping that Pristiq gives me some assistance in accomplishing my goal. I don't think that Pristiq is going to be some kind of miracle weight loss drug - but maybe by getting rid of the Cymbalta, Pristiq will have positive effects on my seratonin levels and my body will not otherwise have the issues I've been dealing with (low metabolism, belly fat gain). Before being treated for depression/anxiety (I'm also taking Xanax as needed), I was stick thin no matter what I ate (obviously changes with age, but I'm only 26). I don't know what's changed, but I want to get back to being happy about myself and my life.

I was working out 4-5 days a week when I first started noticing my belly sticking out further and further. In August of 2008 I had to have my gall bladder removed. I'm sure this has played a factor in my digestive system. I have to take a pill once or twice a day to absorb some of the bile that just sits in my intestine now that bile just flows directly into my intestines instead of being stored in the gall bladder and pumped out when needed. I believe not having the gall bladder can have some effects on the body's ability to emulsify fats - but my doctors have said that if anything, more fats should just be excreted as waste, not digested and stored. On top of the depression issues, I'm also trying to figure out the effects of not having a gall bladder can be.

Thanks to anyone who reads/replies. Any advice is appreciated. I will be starting Pristiq today - I will post updates as things move along.

Matt

Edited by Krash4882

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Posted

Hello,

I am new here also and found this site by searching about Pristiq. I was on 20 mg of lexapro and it never seemed to work that well. After some serious life events my depression got worse so my doctor put me on Pristiq. I am on day 3 and so far am feeling better. At least I want to get out of bed now! I feel a little flat lined but that's ok for me right now.

My depression is much better it seems. Hope this will work. I have cut back my lexapro to 10 mg for 2 weeks then I am supposed to stop it. That scares me a little!

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Pristiq is basically a new form of Cymbalta, so be careful!! If you had negative side effects on Cymbalta, you will probably have them on Pristiq as well. The Wellbutrin may mask the negative Pristiq side effects at first, so monitor your feelings and energy level carefully. If you begin to feel tired, lethargic, and/or apathetic, I encourage you to re-evaluate your use of Pristiq. The Pristiq could be making you worse (like Cymbalta does to many people). Pristiq has only been on the market since Feb. 2008, so there is not much public info available yet.

You may only need the Wellbutrin to help you feel better.

Not true for everybody, I'm new to AD's and started taking Cymbalta about 4 months ago, I started feeling good at first, but then had problems sleeping and getting sleepy with low energy all day. I discussed my issues with my Doc, and he suggested I change to Pristiq and WOW!...what a difference. I've never felt so good before, high energy, focused, no sleepiness, no insomnia...just great.

It's been two weeks on the regular 50mg dose and I have not experienced any notable side effects.

Hope this helps anybody debating the switch.

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Posted

Hello,

I am new here also and found this site by searching about Pristiq. I was on 20 mg of lexapro and it never seemed to work that well. After some serious life events my depression got worse so my doctor put me on Pristiq. I am on day 3 and so far am feeling better. At least I want to get out of bed now! I feel a little flat lined but that's ok for me right now.

My depression is much better it seems. Hope this will work. I have cut back my lexapro to 10 mg for 2 weeks then I am supposed to stop it. That scares me a little!

My name is Dave and I started Pristiq 9 days ago. I am still feeling nausea and dizzy..but i will give it a lot more time for it to take affect. I hope it works. I am at my wits end.

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Pristiq is basically a new form of Cymbalta, so be careful!! If you had negative side effects on Cymbalta, you will probably have them on Pristiq as well. The Wellbutrin may mask the negative Pristiq side effects at first, so monitor your feelings and energy level carefully. If you begin to feel tired, lethargic, and/or apathetic, I encourage you to re-evaluate your use of Pristiq. The Pristiq could be making you worse (like Cymbalta does to many people). Pristiq has only been on the market since Feb. 2008, so there is not much public info available yet.

You may only need the Wellbutrin to help you feel better.

Not true for everybody, I'm new to AD's and started taking Cymbalta about 4 months ago, I started feeling good at first, but then had problems sleeping and getting sleepy with low energy all day. I discussed my issues with my Doc, and he suggested I change to Pristiq and WOW!...what a difference. I've never felt so good before, high energy, focused, no sleepiness, no insomnia...just great.

It's been two weeks on the regular 50mg dose and I have not experienced any notable side effects.

Hope this helps anybody debating the switch.

How did you do the switch from Cymbalta to Pristiq? I have been on Cymbalta for 3 months and my doc and pharmacist disagree on how I should do it . . . any guidance would be appreciated. Also, did you get really sick when you started the Cymbalta?

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Posted

I have gained TONS of weight on Cymbalta and went to the Doctor today and he gave me samples of Pristiq. Who all has tried this? I will be taking it with Lamitical because of Bipolar? Any advice will be appreciated! I had been cutting back on my cymbalta for the past 2 weeks.

that is so weird, i heard cymbalta makes you lose weight, i also have gained. i just got switched today from cymbalta to pristq. Does pristq make yu gain weight??

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Hello, I just joined today, I found this sight when i googled pristq. So how has it been working for you?? :snowman1:

I just joined today and this is my first post. I was diagnosed with low levels of seratonin back in 2006. I tried Prozac for 6 months, felt much better, went off it for 3 months, and started to get down again. My doctor switched me to Lexapro. I tried it for 1 year, and as I continued feeling pretty good, I tried going off it. Within another few months I started noticing symptoms again. I've always had trouble sleeping, problems with headaches/migraines, and just didn't feel motivated to do much of anything. My doctor said that 50% of people can go on an SSRI and come off in 6 months and be fine - the same thing goes for the 12 month "2nd trial." Since it was clear that I was worse off without the help of the medication, I began taking Cymbalta in the summer of 2007 and have recently been on 120mg a day. Over the last year I've noticed quite a bit of belly fat accumulating and became concerned about weight gain. I revamped my diet and began eating more small meals a day, lots of chicken/fish/fresh fruits/veggies, and maintained an exercise regimen. I even purchased and started the P90x workout program but had to stop around day 50 because I found out I have two herniated discs in my back (unrelated, unknown cause). I generally drink 1 gallon of water a day and focus on fresh/organic foods and low sugar snacks/meal replacements. I drink a lot of smoothies and add Acai, L-glutamine, and creatine supplments as well as take Tonalin-CLA to boost my metabolism's fat burning.

NONE of all the things I tried made a difference. I was shocked that I couldn't get rid of ANY excess body fat while going through the rigorous P90X workout program. Since I've been hurt, I haven't been able to exercise much, but I have maintained eating healthy and drinking plenty of water (avoiding pop and other sugar filled drinks). I didn't gain much more weight, but it feels/looks like I've lost some muscle weight and continue gaining fat weight in my abdominal area. This frustration has KILLED my self esteem and has made me feel more depressed than usual. I talked to my doctor about my weight/body fat % concerns and he told me I look fine and not to worry about it. I couldn't accept that and started researching to see if Cymbalta may be part of the problem. Over the last year or so I've felt in kind of an indifferent "fog" - not so many highs and lows, just an every day average feeling. I've noticed that since I've been on Cymbalta I have battled sugar cravings at various times of the day, and found myself snacking all the time, even into the night. I'm doing all I can now to keep snack foods out of my house and not eating anything before bed.

After looking into Cymbalta, from what I could find, several other people seem to attribute weight gain (specifically fat) to being on Cymbalta. After seeing so many commercials about adding Abilify to help with symptoms, and now seeing Pristiq commercials, I started looking into switching to Pristiq. I have read a lot of people's testimonies who have made the switch and they have noticed a better overall feeling and even dropped weight in a lot of cases. I called my doctor and requested to switch over from Cymbalta to Pristiq. I know going off of Cymbalta has a withdrawl period, but my doctor explained that switching right to Pristiq would not be a problem and I shouldn't experience any problems. Maybe it's just a psychological thing and/or something new we're all looking for hope in, but I'm going to give Pristiq a try and see how my body and mind respond to it. Lately I've remained in a depressed fog, and being stuck at home because I can't do much of any physical activity has not helped. I just want to enjoy more things in life instead of constantly thinking about the things I'm unhappy about. I should look forward to walking my dog, taking care of my house, taking good care of myself, and so many other things. Here's to hoping that Pristiq gives me some assistance in accomplishing my goal. I don't think that Pristiq is going to be some kind of miracle weight loss drug - but maybe by getting rid of the Cymbalta, Pristiq will have positive effects on my seratonin levels and my body will not otherwise have the issues I've been dealing with (low metabolism, belly fat gain). Before being treated for depression/anxiety (I'm also taking Xanax as needed), I was stick thin no matter what I ate (obviously changes with age, but I'm only 26). I don't know what's changed, but I want to get back to being happy about myself and my life.

I was working out 4-5 days a week when I first started noticing my belly sticking out further and further. In August of 2008 I had to have my gall bladder removed. I'm sure this has played a factor in my digestive system. I have to take a pill once or twice a day to absorb some of the bile that just sits in my intestine now that bile just flows directly into my intestines instead of being stored in the gall bladder and pumped out when needed. I believe not having the gall bladder can have some effects on the body's ability to emulsify fats - but my doctors have said that if anything, more fats should just be excreted as waste, not digested and stored. On top of the depression issues, I'm also trying to figure out the effects of not having a gall bladder can be.

Thanks to anyone who reads/replies. Any advice is appreciated. I will be starting Pristiq today - I will post updates as things move along.

Matt

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Hi Matt--

How did the switch from Cymbalta to Pristiq go, now that a few more months have passed? Have any others had weight loss after switching?

I have been on Cymbalta for 4 years now and have gained 50 lbs.! First my psychiatrist made it seem like my fault, then my doctor: I was trying to "protect myself" from having contact from others, it was because I wasn't eating well or exercising enough, it was because my metabolism is different because I've entered my 30s, etc. I couldn't understand it because I've always been a healthy eater and had a slim body and small frame before starting Cymbalta. And dieting and doing strenuous workouts have done little to reverse the weight gain. I can't bear to look at photos of myself anymore! For years Cymbalta denied the weight gain side effect, only now it seems doctors have changed their tune. Was glad to read that others had a similar experience of weight gain-- now I know it's not my fault.

I would like to try Pristiq, if others have had luck with weight loss while on it. Cymbalta was working well for 2-3 years, but now it seems like my old irritability and bad temper is returning, and I'm constantly tired in the afternoon and am prone to napping. Could be time to try a new prescription.

--M

Hello, I just joined today, I found this sight when i googled pristq. So how has it been working for you?? :snowman1:

I just joined today and this is my first post. I was diagnosed with low levels of seratonin back in 2006. I tried Prozac for 6 months, felt much better, went off it for 3 months, and started to get down again. My doctor switched me to Lexapro. I tried it for 1 year, and as I continued feeling pretty good, I tried going off it. Within another few months I started noticing symptoms again. I've always had trouble sleeping, problems with headaches/migraines, and just didn't feel motivated to do much of anything. My doctor said that 50% of people can go on an SSRI and come off in 6 months and be fine - the same thing goes for the 12 month "2nd trial." Since it was clear that I was worse off without the help of the medication, I began taking Cymbalta in the summer of 2007 and have recently been on 120mg a day. Over the last year I've noticed quite a bit of belly fat accumulating and became concerned about weight gain. I revamped my diet and began eating more small meals a day, lots of chicken/fish/fresh fruits/veggies, and maintained an exercise regimen. I even purchased and started the P90x workout program but had to stop around day 50 because I found out I have two herniated discs in my back (unrelated, unknown cause). I generally drink 1 gallon of water a day and focus on fresh/organic foods and low sugar snacks/meal replacements. I drink a lot of smoothies and add Acai, L-glutamine, and creatine supplments as well as take Tonalin-CLA to boost my metabolism's fat burning.

NONE of all the things I tried made a difference. I was shocked that I couldn't get rid of ANY excess body fat while going through the rigorous P90X workout program. Since I've been hurt, I haven't been able to exercise much, but I have maintained eating healthy and drinking plenty of water (avoiding pop and other sugar filled drinks). I didn't gain much more weight, but it feels/looks like I've lost some muscle weight and continue gaining fat weight in my abdominal area. This frustration has KILLED my self esteem and has made me feel more depressed than usual. I talked to my doctor about my weight/body fat % concerns and he told me I look fine and not to worry about it. I couldn't accept that and started researching to see if Cymbalta may be part of the problem. Over the last year or so I've felt in kind of an indifferent "fog" - not so many highs and lows, just an every day average feeling. I've noticed that since I've been on Cymbalta I have battled sugar cravings at various times of the day, and found myself snacking all the time, even into the night. I'm doing all I can now to keep snack foods out of my house and not eating anything before bed.

After looking into Cymbalta, from what I could find, several other people seem to attribute weight gain (specifically fat) to being on Cymbalta. After seeing so many commercials about adding Abilify to help with symptoms, and now seeing Pristiq commercials, I started looking into switching to Pristiq. I have read a lot of people's testimonies who have made the switch and they have noticed a better overall feeling and even dropped weight in a lot of cases. I called my doctor and requested to switch over from Cymbalta to Pristiq. I know going off of Cymbalta has a withdrawl period, but my doctor explained that switching right to Pristiq would not be a problem and I shouldn't experience any problems. Maybe it's just a psychological thing and/or something new we're all looking for hope in, but I'm going to give Pristiq a try and see how my body and mind respond to it. Lately I've remained in a depressed fog, and being stuck at home because I can't do much of any physical activity has not helped. I just want to enjoy more things in life instead of constantly thinking about the things I'm unhappy about. I should look forward to walking my dog, taking care of my house, taking good care of myself, and so many other things. Here's to hoping that Pristiq gives me some assistance in accomplishing my goal. I don't think that Pristiq is going to be some kind of miracle weight loss drug - but maybe by getting rid of the Cymbalta, Pristiq will have positive effects on my seratonin levels and my body will not otherwise have the issues I've been dealing with (low metabolism, belly fat gain). Before being treated for depression/anxiety (I'm also taking Xanax as needed), I was stick thin no matter what I ate (obviously changes with age, but I'm only 26). I don't know what's changed, but I want to get back to being happy about myself and my life.

I was working out 4-5 days a week when I first started noticing my belly sticking out further and further. In August of 2008 I had to have my gall bladder removed. I'm sure this has played a factor in my digestive system. I have to take a pill once or twice a day to absorb some of the bile that just sits in my intestine now that bile just flows directly into my intestines instead of being stored in the gall bladder and pumped out when needed. I believe not having the gall bladder can have some effects on the body's ability to emulsify fats - but my doctors have said that if anything, more fats should just be excreted as waste, not digested and stored. On top of the depression issues, I'm also trying to figure out the effects of not having a gall bladder can be.

Thanks to anyone who reads/replies. Any advice is appreciated. I will be starting Pristiq today - I will post updates as things move along.

Matt

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