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Adding Cymbalta To Remeron


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#1 House Cat

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Posted 20 June 2008 - 12:22 PM

I'm taking remeron for depression and amytriptyline for neck pain. My pain doctor recommended I try cymbalta instead to help with pain relief. I got some from my regular doctor. Tapered down the remeron from 60 to 30 for a week, then stopped for a week.... then read more details about cymbalta and how it doesn't mix well with amytriptyline so I spent another week without the remeron while I stopped the amytriptyline to let it flush out of my system. So Ive spent the last three weeks thus:

#1 half dose remeron, full dose amytriptyline
#2 no does remeron, full dose amytriptyline
#3 no does remeron, no dose amytriptyline

I was planning on starting the cymbalta in the next day or two, but I completely fell apart without the remeron last night so I went back on it. I had no choice, it was bad. Very bad. I cant get off it long enough to let it flush out to start the cymbalta. So what I want to know is: can I keep on the remeron and start the cymbalta as well

#2 Isabeau

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Posted 20 June 2008 - 10:01 PM

Hey House Cat,

None of us here are professionals to give you that sort of advice, so the best thing you can do is go and see your doctor or contact them and tell them how you are feeling.

He/She will know what is best for you,

HUGS
Isabeau :hearts:

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#3 X-ray

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Posted 21 June 2008 - 07:24 AM

I'm taking remeron for depression and amytriptyline for neck pain. My pain doctor recommended I try cymbalta instead to help with pain relief. I got some from my regular doctor. Tapered down the remeron from 60 to 30 for a week, then stopped for a week.... then read more details about cymbalta and how it doesn't mix well with amytriptyline so I spent another week without the remeron while I stopped the amytriptyline to let it flush out of my system. So Ive spent the last three weeks thus:

#1 half dose remeron, full dose amytriptyline
#2 no does remeron, full dose amytriptyline
#3 no does remeron, no dose amytriptyline

I was planning on starting the cymbalta in the next day or two, but I completely fell apart without the remeron last night so I went back on it. I had no choice, it was bad. Very bad. I cant get off it long enough to let it flush out to start the cymbalta. So what I want to know is: can I keep on the remeron and start the cymbalta as well


Hello House Cat,

I think that Remeron and amitriptyline is a bad combo.
Those drugs don't go well together.

If you google "drug interactions" you will get many answers.
You can check the combo of Remeron and Cymbalta for yourself.

Amitriptyline can help both with depression and pain.
It's not a modern drug, so the side-effects are bad.

Remeron is good for sleep, but you will need something for your pain.
Cymbalta is approved for depression and nerve pain.

Best of Luck,
X-ray

#4 idleinn

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Posted 21 June 2008 - 01:14 PM

I have just switched to cymbalta from other ssri and combos ( effexor , mirtazapine and lithium )for the same reason to help with nerve pain which has been caused by 8 broken vertabrae. Two weeks after starting i am back at work dep has started to lift and have been able to stop pain meds all together.

All the best ...have a nice day...

#5 House Cat

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Posted 22 June 2008 - 12:35 AM

I'm taking remeron for depression and amytriptyline for neck pain. My pain doctor recommended I try cymbalta instead to help with pain relief. I got some from my regular doctor. Tapered down the remeron from 60 to 30 for a week, then stopped for a week.... then read more details about cymbalta and how it doesn't mix well with amytriptyline so I spent another week without the remeron while I stopped the amytriptyline to let it flush out of my system. So Ive spent the last three weeks thus:

#1 half dose remeron, full dose amytriptyline
#2 no does remeron, full dose amytriptyline
#3 no does remeron, no dose amytriptyline

I was planning on starting the cymbalta in the next day or two, but I completely fell apart without the remeron last night so I went back on it. I had no choice, it was bad. Very bad. I cant get off it long enough to let it flush out to start the cymbalta. So what I want to know is: can I keep on the remeron and start the cymbalta as well


Hello House Cat,

I think that Remeron and amitriptyline is a bad combo.
Those drugs don't go well together.

If you google "drug interactions" you will get many answers.
You can check the combo of Remeron and Cymbalta for yourself.

Amitriptyline can help both with depression and pain.
It's not a modern drug, so the side-effects are bad.

Remeron is good for sleep, but you will need something for your pain.
Cymbalta is approved for depression and nerve pain.

Best of Luck,
X-ray

I've been doing remeron and amytriptyline for several years now with good effects. They may not play nice with other people, but the play nice together with me.

I know amytriptyline is out of date, but it has been a miracle worker for my pain. The first time I used it I was on 50mg a day and it completely resolved my neck pain. Unfortunately I can't run that dosage for any length of time because the side effects slowly build and they are harsh when they hit full steam. But I'm now on it 20mg a day and when work requires more physical effort I bump it temporarily to 30mg a day and that helps when needed. As bad as the side effects are I'm better off with it than without it (assuming I control the dosage).

So back to the original point: is anyone using remeron and cymbalta together successfully/safely?

#6 moonlightress

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Posted 22 June 2008 - 04:22 AM

I know amytriptyline is out of date, but it has been a miracle worker for my pain.

Actually, it's still being used a lot. It doesn't work as specifically as the newer drugs, which means more side effects, but when the newer drugs fail, the older ones get used with good success.
I took amitryptiline for chronic headaches, just 10mg, worked very well AND I slept so well.

#7 edgeoftheocean

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Posted 25 February 2009 - 01:38 PM

I AM TAKING REMERON AND CYMBALTA TOGETHER

Hello Everyone,
I guess I'm the guinea pig that's taking both remeron and cymbalta at the same time. I am taking them together (15 mg remeron at night before bed, and 30mg cymbalta in the morning), my doctor has told me that I am at risk of serotonin syndrome. I'm taking both for anxiety, not depression. The side effects of cymbalta as far as I can see are 50/50. You don't have muscle pain (thank goodness, because the muscle pain from remeron was brutal), it curbs your appetite (makes you nauseous), you feel significantly more alert without being scared (unlike the common side effect of anxiety in conjunction with alertness I experienced on Wellburtin XL). The negative side effects (for me) however are sexual disfunction, stomach pain, hot flashes, skin sensitivity, exhaustion by 10pm ('crashing') and apparently some people have lost their monthly visitor as well. I want to stop taking remeron completely and just stay on cymbalta as I've gained 50-60 lbs since starting remeron in June of last year (by far the heaviest I've ever been, and hating it), but I have to talk to my doctor and see what he prescribes.

#8 ssda72

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Posted Yesterday, 05:37 PM

I realize this is an old post, but it came up as one of the top links when i looked up "adding Remeron to Cymbalta".

I have been taking Cymbalta for a few months now (currently on 60 mg, but had went up to 90 mg at one time). My psychiatrist has added Remeron to the mix and has upped the dosage to 30 mg just today. I recently had an accident (falling down some cement stairs outside my apt complex, broken arm and 3 breaks to my ankle requiring surgery). And all of that has made me almost home-bound due to having to be in a wheelchair because of the broken arm.

When I had my visit today I mentioned to the doctor that I was feeling pretty "blue" a lot here lately and that I'm sure this whole accident situation is probably the cause. That is when he upped the Remeron to 30 mg. He explained how both Cymbalta and Remeron work and why they work well together. Understanding that helped a lot, at least for my over inquisitive mind. So I would encourage anyone who is on this combo to talk to their doctor to get this same information.

 

So we'll see if it helps (going back to 90 mgs on the Cymbalta is not an option for me).

 

Again, I know this is an old thread, but i just had to comment on the above post from "Newbie". This person said they were prescribed 15 mg of Remeron at night and 30 mg of Cymbalta in the morning, both for anxiety. Remeron is an anti-depressant that is prescribed for depression. Cymbalta works for both anxiety and depression. Also, I noticed that this person said they were taking these medications for anxiety only, not depression. Then my question to that person would be why were they ever prescribed Wellbutrin, because it is for depression only.

Anyway, who knows. It was just a thought.

 

Having both (anxiety and depression, while not being bipolar) limits the medication that will help. But after taking a plethora of different ones, I'm so far happy with Cymbalta. Like others has said, it helped with depression pains as well as some psychosomatic pain I was having.

 

I have no real reason for posting this except to say that I too am on the combo. and my thoughts to others from my experience only is that I changed the time I take my Cymbalta from nightly to in the morning. it seemed to work better. But now that I'm taking the Remeron in conjuction with it, I may have to go back to nightly. They are supposed to work together, so it would seem that they would need to be taken together. the remeron does make me sleepy. The Cymbalta does not make me sleeply anymore (after you hit that 8 weeks mark, it gets better as far as the side effects go). But i don't know , I wished I would have remembered to ask the doctor if it would work better if they were taken at the same time. If anyone does read this, and knows, please let me know.

 

Thanks!






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