Generic Wellbutrin Does Not Work!
Posted 31 March 2008 - 05:07 PM
Hope this helps someone!!
Posted 31 March 2008 - 05:20 PM
For those out there not having luck with Wellbutrin, I just want you to know that the name brand is the only way to go. Several dr's are seeing a "crash" with patients who go to the generic brand. Since it is not regulated, the medicine can be as low as 20% strengh as the name brand. Please discuss this with your dr. I had a major crash after going from 150 mg name brand to 300 mg generic.
Hope this helps someone!!
My Prescription that I'm going to start today is:
Posted 31 March 2008 - 06:21 PM
Even though it's not name brand, it still has to pass F&D regulations. How do they get away with making it so much weaker? That can actually be quite dangerous to people. It *could* cause a seizure!
Since you are just starting the bupropion, you do not have to worry about the seizure from sudden withdrawal that I'm referring to. My advice to you is just as I said on your thread. Meditate, exercise or do what ever it is you do to relax and go with it. It does sound like your doc knows what s/he's doing. Please try to relax.
Posted 31 March 2008 - 07:08 PM
Two weeks prior to Dr. Temple's remarks, on December 1, 2007, the United States Pharmacopeia (USP) officially released information indicating that the dissolution of the Budeprion XL 300 varied significantly from the original drug. According to the USP, tablets of Wellbutrin XL release only a small amount (less than 20%) of drug during the first two hours of dissolution. In contrast, the Budeprion XL releases at least 25% and as much as 50% of its drug in that period. These USP dissolution standards are based upon performance characteristics that the FDA approved for the original and generic drugs, respectively, and were provided to USP by the manufacturers.
edient and binders, etc. Also the FDA regulations for dissolution are rather broad. This can be a problem with a drug such as Wellbutrin.
Posted 31 March 2008 - 08:48 PM
Some people experience a crash when increasing from 150mg to 300mg, regardless of brand. The effective dose is different for everyone. Some people do very well on 150mg, but feel terrible on 300mg. Unfortunately, it takes some trial and error to find the right brand and dosage for you.
Edited by suburgatory, 31 March 2008 - 08:49 PM.
Posted 02 April 2008 - 04:34 PM
Posted 10 April 2008 - 06:30 PM
I felt almost nothing at 300 for a month and went to 450 and crashed hard for the past week. Horrible dark depression and tried all day...zombie-like...never go outside...confusion...
only positive is I stopped smoking
For a month I was taking Wellbutrin XL in the brand name bottle---samples form the Dx. Then I got a prescription for Bupropion ER 150 (Generic for Wellbutrin SR)
Can there be a difference between XL & SR? Does it really matter that much?
Edited by pocketplayer, 10 April 2008 - 06:32 PM.
Posted 11 April 2008 - 12:21 AM
XL is longer lasting and is only taken oncer per day, whereas SR is made to be taken twice per day. So the amount of drug in your system at any given point could very well be different between the two preparations.
Thank you! I'm pretty pi**ed off right now hearing this. When I went to the pharmacist to fill my prescription, it was for XL. They gave me generic which is SR. The pharmacist said I could take them all at once like I did the XL. My life the past five days has been horrible! I am going to visit this pharmacy.
I will try the SR three times per day--morn, noon, night
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