Almost on day 2 of Remeron (30mg) - was given it for sleep, appetite, and depression. My psychiatrist made it clear it was mainly to help the first 2, but said it should elevate my mood as well. He prescribed it to me because he believed I didn't have clinical depression, and that with therapy and with certain changes in my life it would give me that extra boost. I recently had a bad experience with Cipralex (20mg) where it didn't agree with me AT ALL as it severely worsened my depression, so I was a little hesitant to try another AD.
So far I've noticed my appetite sky rocket as if I were working out twice a day again. Food tastes great, and I'm eating a lot more of it. It made me drowsy after taking it but I was also taking T3's at the time of taking it. As for my mood, I'm not sure if it's because I was discharged from the hospital and finally got to go home, but I haven't felt this happy in a long time. I didn't get any sleep last night since I've been so excited. My fingers are crossed that it keeps going good for me and that it helps with my insomnia.
PinkFloyd! Glad you're having a good response so far! Based on my own experience I would say IF things get worse again before getting better, don't panic, that does happen for some of us. Side effects generally reduce with time. Beware the weight gain, I've had the appetite thing too and have put on maybe 10 pounds in the couple months... but the positive effect for me is worth it :)
I started Remeron a few months ago as an add-on to the Effexor i was already taking. Effexor was interfering with my sleep and the Remeron counteracts that. Also the two supposedly have a "synergistic" effect in the way they each affect norepinephrine & serotonin.
I had tried Remeron alone for depression years ago and hated it; it just seems to work better for me in combo.