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Depression Forums - A Depression & Mental Health Community Support Group _ OTHER DEPRESSION & ANXIETY MEDICATIONS _ Topomax (Topiramate ) FAQ's

Posted by: Lindsay Jun 25 2004, 03:32 AM

Topomax is used in the adjunctive treatment of partial onset seizures in adults and pediatric patients ages 2 to 16 years, in Binge-eating disorder, and to treat bipolar disorder.
Add on treatment for primary generalized tonic-clonic seizures in adults and children, 2-16 years old.


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CLASS: Anticonvulsant.
Generic name:
Type:

Strengths:

Tables:
25 mg, 100 mg, 200 mg.

Dosages: Actual dosage must be determined by a physician.

Adult

Oral:
Start: 50 mg.
Increases: 50 mg each week for eight weeks, until the dose is 400 mg/day.
Maintenance: N/A
Maximum: 400mg daily, in 2 divided doses.

NOTE: If CCR < 70 mL/1.73 m2, use one half of the usual adult dose.

Children, 2-16 years

Oral:
Start: 5-9 mg/kg/day in two divided dose.
Increases: N/A
Maintenance: N/A
Maximum: N/A

Normal dosage:

Adult: 200mg daily, in 2 divided doses.

Problems with:
Liver Function: Lower dosage with care, increase as needed.
Kidney Function: Lower dosage with care, increase as needed.

The metabolic breakdown of Topomax will be reduced increasing the duration and intensity of its effects.

Test:
Before taking: Liver / Kidney.
While taking: Liver / Kidney.

Take With:

Full Benefits In: Up to four weeks.

Missed Dose(s):  If within one hour take, if over an hour skip and then continue on your normal schedule.
Never Take a Double Dose!

If Stop Taking:  Do not stop without consulting your physician and never abruptly are you may develop withdrawal seizures.

Overdose symptoms include:  N/A.


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Warnings

Patients with hepatic function impairment may have increased Topiramate plasma concentrations and a dosage adjustments may be needed.

Avoid alcohol while taking this drug.

Use extra caution if you have any liver or kidney impairment. ( The metabolic breakdown of Topomax will be reduced increasing the duration and intensity of its effects ).

Topomax may increase the frequency of kidney stones.

The habit-forming potential is

Do not take this drug if you are pregnant. ( Only take if the mother's or baby's life is endangered )

Do not take this drug if planning to become pregnant. Do not take if you are breast-feeding.

Do not give this drug to anyone under the age of two years.

Only use drug in small doses at first if over sixty and with close monitoring.

Do not use if: You had negative reactions to this drug in the past.

Inform your Doctor if: You had negative reactions to this drug in the past.


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Topomax ( Symptoms or Effects )

Common: Anxiety, depression, sedation, speech problems, double vision, abnormalities in vision, decreased appetite, impaired cognition, memory impairment, dizziness, impaired muscular coordination, tingling in the extremities, an unsteady gait, nausea, respiratory infections, or weight loss.

Rare: Weight gain.

See physician always: Anxiety, depression, sedation, speech problems, double vision, abnormalities in vision, decreased appetite, impaired cognition, memory impairment, dizziness, impaired muscular coordination, tingling in the extremities, an unsteady gait, nausea, respiratory infections, weight gain, or weight loss.

See physician if severe:

See physician NOW:

Stop taking and see physician NOW: