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Burgy
post Jan 17 2008, 10:57 AM
Post #1


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This is a subject that I feel is important enough for its own topic. I have experienced this effect myself, and witnessed it in most people who start this medication.

Bupropion (Wellbutrin, Zyban, Budeprion) has a unique startup effect, a sort of honeymoon, or mirage in the dessert. When first starting, it can give an instant high, bringing lots of energy, and completely relieve depression. This may be caused by the fact that bupropion is chemically related to amphetamine. Having experimented a few times with meth in my 20s (bad boy, I know) I can say that the feeling is similar, although bupropion is not as intense and doesn't alter you the way meth does (or ruin your life, etc.), thank goodness.

Like all highs, this effect wears off and you fall back to where you were before, which can feel even worse than before, because you were given a glimpse of happiness and relief. This can be very confusing and discouraging, and make you think that bupropion has already given up on you. It hasn't. Like most antidepressants, you have to give it the full 6-8 weeks to build up and stabilize, although you should start feeling better sooner than that. Once you have fully adjusted, you'll enjoy the energizing and brightening effects, although it won't be as intense as the false high in the beginning.

I see so many people go through this and post about it, and I hope that devoting a topic to the subject will help those who are new and struggling with the startup process. By the way, I am on 300mg XL, and loving it. It's a wonderful antidepressant in my opinion, that has lifted me out of the often suicidal darkness I was stuck in for years. I think it's important for people to know that you might have a very difficult startup, so please try to hang in there and give it the full 2 months. Only then will you know what it can really do for you.


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We are what we think. All that we are arises with our thoughts. With our thoughts, we make the world. ~Buddha
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Posts in this topic
- Burgy   The Wellbutrin Honeymoon   Jan 17 2008, 10:57 AM
- - MichaelBlue   The big teaser, indeed! Many thanks to Burgy...   Jan 17 2008, 02:45 PM
- - manckar   i`m pesimestic now :( i`m on my seventh w...   Jan 17 2008, 05:06 PM
|- - Burgy   manckar, In my experience, the people who don...   Jan 17 2008, 09:05 PM
- - Lucinda   Yep, when I first started WB it was like drinking ...   Jan 18 2008, 12:09 AM
|- - Elizabeth007   QUOTE (Lucinda @ Jan 18 2008, 12:09 AM) Y...   Mar 12 2008, 02:03 PM
- - Deet   Yah, Burgy, I had that experience in July...I reme...   Jan 18 2008, 09:08 AM
- - MichaelBlue   Correction, Deet: We ARE the research. We...   Jan 18 2008, 04:07 PM
- - slw   the amphetimine idea makes perfect sense -- my son...   Jan 18 2008, 04:13 PM
- - LA_Woman   I totally experienced the honeymoon thing too. It ...   Jan 18 2008, 04:20 PM
|- - Lek   Well, since this is for research purposes ... I...   Jan 18 2008, 06:03 PM
|- - Burgy   Lek, my flatulent friend! I'm so glad ...   Jan 19 2008, 11:36 AM
- - aaronteds   I'm really glad to hear the "meth-y...   Jan 29 2008, 05:47 PM
- - MichaelBlue   Aaron- No question. I felt it, too, after just ON...   Jan 29 2008, 06:38 PM
|- - Tannor   I just started it yesterday generic 100 SR, and ha...   Jan 30 2008, 12:10 PM
|- - gaugreg1x   It will take significantly longer than one day t...   Jan 30 2008, 01:25 PM
||- - Tannor   QUOTE (gaugreg1x @ Jan 30 2008, 06:25 PM)...   Jan 30 2008, 01:53 PM
|- - Dark Priestess   QUOTE (Tannor @ Jan 30 2008, 01:10 PM) I ...   Mar 18 2008, 04:59 PM
- - aaronteds   Well, my Wellbutrin honeymoon is definitely over, ...   Feb 6 2008, 06:37 PM
|- - Burgy   QUOTE (aaronteds @ Feb 6 2008, 03:37 PM) ...   Feb 7 2008, 10:51 AM
- - MichaelBlue   Aaronteds: Sorry to hear this. Some people do b...   Feb 7 2008, 08:51 AM
- - no1really   I experienced a similar 'honeymoon' phenom...   Feb 9 2008, 01:55 AM
- - Niffer   OMG! I am so excited I found this thread!...   Feb 10 2008, 11:31 AM
|- - Burgy   I'm so glad I could put your mind at ease ((((...   Feb 10 2008, 12:06 PM
|- - Niffer   QUOTE (suburgatory @ Feb 10 2008, 01:06 P...   Feb 10 2008, 01:34 PM
|- - Beanchop99   QUOTE (Niffer @ Feb 10 2008, 12:34 PM) QU...   Feb 10 2008, 01:52 PM
- - Niffer   Here is what I posted in the other topic. I though...   Feb 10 2008, 03:02 PM
- - Mimen   On WN now for just over 2 months. Never experience...   Feb 19 2008, 01:38 PM
|- - Burgy   It's nice to hear some people can respond grad...   Feb 19 2008, 01:41 PM
|- - SublimeDysfxn   QUOTE (Mimen @ Feb 19 2008, 10:38 AM) On ...   Jan 4 2009, 11:39 PM
- - CinCity   QUOTE (suburgatory @ Jan 17 2008, 07:57 A...   Feb 19 2008, 10:34 PM
- - Beanchop99   Cindy: Are you taking Lex and WB? Or just Lex? ...   Feb 21 2008, 12:42 PM
|- - ecstatichappy   Interesting topic, sburgatory and helpful too. I...   Feb 27 2008, 06:52 PM
|- - Burgy   ecstatichappy, It sounds like you're reacting...   Feb 29 2008, 01:02 PM
||- - recovery   Initially was prescribed Wellbutrin 100mg SR taken...   Mar 4 2008, 03:09 PM
||- - ecstatichappy   I think it's very hard to predict whether anyo...   Mar 4 2008, 03:53 PM
||- - recovery   Thanks for the encouraging words, ecstatichappy. ...   Mar 6 2008, 12:13 PM
|- - Mimen   LOL you wont jinx yourself! Wellbutrin works e...   Mar 14 2008, 11:37 AM
- - Danielson   I'm in my 4th week on wellbutrin, along with ....   Mar 11 2008, 09:07 PM
|- - Mimen   Danielson hi, I don't know about the Zanax as ...   Mar 12 2008, 01:08 AM
- - ctoro   Thank you for posting this. I had this honeymoon p...   Mar 21 2008, 09:51 PM
- - historyteach   I am on 100 mg of Wellbutrin twice a day. I am for...   Mar 22 2008, 09:04 AM
|- - Burgy   Hi historyteach, Instead of choosing either WB or...   Mar 22 2008, 10:51 AM
- - historyteach   Thanks, subburatory, I've had SSRI's befor...   Mar 22 2008, 11:58 AM
- - woodscamper   I am into just over two weeks on WB XL 300 mg. B...   Mar 25 2008, 12:50 AM
|- - EndTheStigma   So I started taking 150mg (up to 300mg after 3 day...   Mar 26 2008, 10:31 AM
|- - Burgy   Yes, things will get much better, so please try to...   Mar 26 2008, 10:43 AM
- - kgill78   I started wellbutrin sr (150mg) about a week or so...   Jun 2 2008, 02:10 AM
|- - RVQueen57   QUOTE (kgill78 @ Jun 2 2008, 02:10 AM) I ...   Feb 3 2009, 03:09 PM
- - RedneckCowboy   Day Four... Right on the nose, the 'Honeymoon...   Jun 7 2008, 09:10 AM
|- - Burgy   Hey RC, As I responded to your other post, I thin...   Jun 7 2008, 09:40 AM
|- - KarenRB53   QUOTE (suburgatory @ Jun 7 2008, 10:40 AM...   Jun 11 2008, 08:55 AM
|- - Burgy   QUOTE (KarenRB53 @ Jun 11 2008, 05:55 AM)...   Jun 11 2008, 10:23 AM
|- - moonlightress   QUOTE (suburgatory @ Jun 11 2008, 05:23 P...   Jun 12 2008, 01:56 AM
- - daughty   Hi, I am now to these forums; I discovered them wh...   Jul 14 2008, 08:33 AM
|- - Burgy   to DF, (((((daughty))))) I got everything except ...   Jul 14 2008, 11:19 AM
- - daughty   Hi Burgy, thanks for the warm welcome and for your...   Jul 15 2008, 03:44 AM
- - aries woman   Oh I'm so glad the internet exists. I...   Jul 26 2008, 02:09 AM
- - Burgy   I've heard from a few people recently who are ...   Oct 2 2008, 11:01 AM
- - Chenderson   My honeymoon was great! It was like I took an ...   Oct 3 2008, 02:41 PM
|- - Burgy   Hang in there, (((((Chenderson)))))!! I kn...   Oct 3 2008, 02:45 PM
||- - Chenderson   QUOTE (Burgy @ Oct 3 2008, 02:45 PM) Hang...   Oct 3 2008, 03:08 PM
||- - Burgy   QUOTE (Chenderson @ Oct 3 2008, 12:08 PM)...   Oct 3 2008, 03:41 PM
|||- - Chenderson   QUOTE (Burgy @ Oct 3 2008, 03:41 PM) QUOT...   Oct 3 2008, 04:26 PM
||- - andiepants   QUOTE (Chenderson @ Oct 3 2008, 03:08 PM)...   Jan 6 2009, 02:51 AM
||- - SoulSearching   Thank you for posting this topic Burgy! This m...   Jan 9 2009, 11:59 AM
|- - Lindsey22   QUOTE (Chenderson @ Oct 3 2008, 11:41 AM)...   Oct 3 2008, 03:00 PM
- - debiski   I am on day three of Wellbutrin at 100mg. I have f...   Oct 9 2008, 01:47 PM
- - Angeldoggies   You all cannot imagine how much your posts mean to...   Oct 10 2008, 10:01 AM
- - jr ranger   hey there. thanks so much for starting this thread...   Oct 15 2008, 09:34 PM
- - givemepeace   I think my honeymoon only lasted about a week, the...   Oct 16 2008, 06:17 AM
- - webkangaroo   Burgy: I also just wanted to thank you very much ...   Oct 26 2008, 08:37 PM
- - givemepeace   Yeah, the sleep deprivation is the hardest part fo...   Oct 27 2008, 06:18 AM
|- - moonlightress   RE: The Wellbutrin Honeymoon   Nov 13 2008, 09:19 AM
- - Guru   Hi All, After taking 10mg Lexapro for about 9 wee...   Nov 19 2008, 01:47 PM
|- - Burgy   QUOTE (Guru @ Nov 19 2008, 10:47 AM) Did ...   Nov 19 2008, 02:13 PM
|- - Guru   QUOTE (Burgy @ Nov 19 2008, 02:13 PM) QUO...   Nov 19 2008, 04:00 PM
|- - s_frye   Thanks, Burgy and everyone else for contributing t...   Nov 19 2008, 07:11 PM
- - NJosh   How long did it take for you guys to feel this ...   Dec 30 2008, 01:41 AM
- - lisarowe   I wish the Honeymoon Stage wasn't the Honeymoo...   Jan 1 2009, 11:10 AM
- - LunchLady   hey all! i been on Wellbutrin for 2 days now. ...   Jan 1 2009, 12:15 PM
|- - Burgy   QUOTE (LunchLady @ Jan 1 2009, 09:15 AM) ...   Jan 1 2009, 12:51 PM
|- - oswing   Hi there! I have a question for you Burgy: ...   Jan 15 2009, 09:43 AM
|- - Burgy   No problem, Olivier. When I first increased to 30...   Jan 16 2009, 06:56 PM
|- - oswing   Thank you very much Burgy. It is true that WB is ...   Jan 19 2009, 06:52 AM
|- - Burgy   True, WB is chemically unique and works differentl...   Jan 19 2009, 05:50 PM
|- - oswing   Yes! I also think you can stand back: I gather...   Jan 20 2009, 10:36 AM
|- - oswing   Woops! My post went away on its own... Just...   Jan 20 2009, 10:42 AM
|- - Burgy   I'm pretty sure XR (also called ER) is extende...   Jan 20 2009, 06:33 PM
- - SublimeDysfxn   i am on day 5. if anyting it makes me slightly dr...   Jan 4 2009, 11:30 PM
- - JJ67   Wow this is interesting stuff. I am on Lexapro 20...   Feb 5 2009, 06:12 PM
|- - sojo   I'm definitely on the honeymoon phase right no...   May 25 2009, 12:10 PM
- - Darken   Hi Sojo, Glad to hear your first few days on We...   May 25 2009, 12:30 PM
- - griz47   Well i definetly experianced the honey moon effect...   May 26 2009, 04:21 PM
|- - sojo   QUOTE (griz47 @ May 26 2009, 01:21 PM) We...   May 27 2009, 12:08 PM
- - pbreno   Hi Everyone. A little about me.. male, 41, divorc...   May 29 2009, 03:42 PM
|- - Darken   QUOTE (pbreno @ May 29 2009, 03:42 PM) Hi...   May 29 2009, 04:18 PM
- - pbreno   Things are feeling leveled out for me now. What I...   Jun 2 2009, 08:52 AM
- - PetersKeys   QUOTE (suburgatory @ Jan 17 2008, 10:57 A...   Jun 19 2009, 05:12 PM
- - renmo27   Hi. 27yr old male here. I just want to start off ...   Jun 19 2009, 09:29 PM
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