Have taken long term prior (since 2003), mirtazapine, strattera, wellbutrin, trazadone at least in terms of AD's

Mirtazapine allowed me to sleep better initially, but did nothing for me after getting used to it. Same with trazadone.

On the stimulating side,
Strattera was too agitating. Wellbutrin did nothing.

Starting Zoloft in hopes an ssri might work out.

All these drugs were meant to combat insomnia/fatigue, somehow treating it through sedative or stimulating side effects. Nothing worked long term, even after the first few days of getting used to the drug.

If an SSRI doesn't work, where to next?

I have a whole history migrating from Ambien/Sonata, through alternative sedatives like mirtazapine and gapapentin, through stimulants like Provigil and Adderall, and giving up somewhat the last few years due to the lack of success on these and dwindling options.

Kinda running on the assumption with the SSRI that maybe I have some underlining depression that is somehow causing the insomnia and fatigue. I certainly have my depressed and manic moments, but these are so closely tied with energy I don't know what comes first.

Hi randomthoughts,

God you really have tried a lot of meds. How frustrating. I think it's easy to find some benefits on most things but finding one that does everything is hard. I would love to find something that would stimulate me.
Good luck with the zoloft. Let us know how you get on.

PRT xx

I will say that Zoloft helps me get out of bed and get going easier. I don't need as much coffee to "wake up" in the morning. However, later on in the day it can make me feel tired. Not sure why it works that way, but for me, it does. I'm thinking about going to the doctor and telling him about it because I don't like feeling so tired at night. I work second shift so from 9pm until I get out of work I'm usually very fatigued. I find that getting up and doing something constructive really helps though.

25mg this morning seems to be "working" ok after about an hour... supposed to stay on this for six days.

If a week from now I find sertraline is at all stimulating for even a few hours during the day, I think I'll be pretty impressed! Likewise if it makes me drowsy at night. Will certainly report on any findings.

I did have "stimulatng"(lol) after the first couple of weeks. It's so long ago now I'm not sure ifithappened that fastlol