Hi all. Today begins Week#5 for me on the Lexapro. I have to say that I feel less anxiety and less of that "zoned-out" feeling from the first three weeks. But my mood is still very, very low. Still feel "stuck" in that joyless hole of depression, with low motivation to do much of anything. Before the depression hit me a few months ago, I was really productive and energetic. So my frustration is boiling at times.

As I wait and wonder if the medicine will fully kick in, I just saw a new study (released today) in Canada that is encouraging. Researchers (in collaboration with the drugmaker) found that Lexapro is as effective in a "real-world" setting for major depressive disorder as it has been shown to be in clinical trials. Some 647 patients enrolled in the trial, and 71% completed the 6 months of treatment. Of those, 78% responded very well to the med. I'll post the full story in the Depression&Meds section of the forum.

Regards, and hope to hear from others.