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post Sep 25 2007, 11:28 AM
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Hello everyone!

This is day 6 of Wellbutrin 150 mg. XL for me.

I had tried it back in June and only lasted 10 days, and it caused my arm between the elbow and shoulder to go into spasms. I have Essential Tremors and many of these meds do cause the tremors to be worse, however the spasm scared me, as I was afraid it might become irreversible.

In desperation though I am back on the Wellbutrin, as the depression was simply out of control.

So far my tremors are slightly worse, but no spasms yet.

I am feeling no other side effects except for insominia.
The insominia started trhe very first night. I am usually the Queen of sleep, fall asleep easy, stay asleep, and sleep way too much especially during severe depressions.

On the very first night, and every night since I can not go to sleep. I have been taking Rozerem, but that doesn't help, then I get up and take one half of an Ativan and that will put me to sleep.

Before I started Wellbutrin, it was a very rare occassion for me to have to use a sleep aid.

My question is, does this insominia problem get better after a few weeks, or does a person need a sleep aid forever while on Wellbutrin.

I really hate taking a med that causes you to have to take another med to counteract something it is doing.

Somehow, I escaped the use of illegal drugs, never even smoked pot, and this taking Wellbutrin, then having to take a sleep med is to me somewhat like taking uppers and downers, or at least that is what my brain is trying to tell me at the moment.

On the positive side of things. The Wellbutrin slowed , almost stopped the suicidial thoughts from the very first day also.
My deprssion has gone from severe to less severe, and today for the first time in weeks, I am doing laundry, doing the dishes etc.---My heart isn't completly into it, and I am slow, but I do have the mental will power to just not give up. That is a huge improvement from where I have been since March.

Hope each day gets a little better, and above all I hope I can find a way to deal with the spasms if and when they start, and that they will go away.

Oh, I did ask the question back up there somewhere about sleep, would appreciate your experience with this.
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jillyo
post Sep 28 2007, 09:35 AM
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Yo.

Well, I'm on my third day on Wellbutrin XL (150 mg). So far I've noticed it's given me an attitude. That's about it. I know I have to wait for about 8 weeks for it to truly kick in, but dang I'm impatient. But I did notice a good thing right away. It made me more alert. When I was on Zoloft, I was draggin big time. I'm also taking Depakote. Oh, quick question: I've been brusing very easily. Is that a side effect of Depakote?

Alrighty, TTYL!
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lambvet
post Sep 28 2007, 10:52 AM
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QUOTE(jillyo @ Sep 28 2007, 07:35 AM) *
Yo.

Well, I'm on my third day on Wellbutrin XL (150 mg). So far I've noticed it's given me an attitude. That's about it. I know I have to wait for about 8 weeks for it to truly kick in, but dang I'm impatient. But I did notice a good thing right away. It made me more alert. When I was on Zoloft, I was draggin big time. I'm also taking Depakote. Oh, quick question: I've been brusing very easily. Is that a side effect of Depakote?

Alrighty, TTYL!


Hi Jillyo,

You should talk to your doctor soon, Depakote may be involved but you really should disclose this type of concern for an accurate assessment of how you could be reacting to any medication. Our meds can have a variety of SEs, even those that are rare and you might not usually hear about. Years ago, although I am probably much older than you and have a history of alcohol abuse, but again, years ago, the pDoc I had back then suspected that I might be BP, since then NOT, but at the time she had me take a liver test and then checked my liver every 8 weeks until I finally changed to gabapentin. I never had any liver abnormalities, but sometimes Depakote can cause them. So she just wanted to be safe because of my history. So definitely let your doc know about your bruising if it is abnormal. Good advice for any abnormality you might notice with any med.

Peace and Love.... wayne


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Jamielove21
post Sep 28 2007, 05:18 PM
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I've been on WB for 3 days now. I've taken Paxil for about 7 years, and didn't like the weight gain and the "dead" feeling. I am no longer feeling dead, and im wondering if this is what I should be feeling?? I've felt pretty upbeat for the last 2 days. Today im kind of down. It "could" be outside factors. I'm not suicidal, but I wish the higher power would just take me out of this life. Anyone know the feeling?
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Sheepwoman
post Oct 1 2007, 04:15 PM
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Hi, Jamielove,
A lot of people experience a lifting of spirits when starting a new med. It can be bumpy, though, ranging from good to not so good with moods. It can take up to 8 weeks and maybe some dose adjustments to get the full benfits. What dose are you on?

Hang in there and be patient.
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superman19
post Oct 2 2007, 02:38 AM
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QUOTE(Jamielove21 @ Sep 29 2007, 12:18 AM) *
I've been on WB for 3 days now. I've taken Paxil for about 7 years, and didn't like the weight gain and the "dead" feeling. I am no longer feeling dead, and im wondering if this is what I should be feeling?? I've felt pretty upbeat for the last 2 days. Today im kind of down. It "could" be outside factors. I'm not suicidal, but I wish the higher power would just take me out of this life. Anyone know the feeling?

I know the feeling that you are talking about. I always have it when i have a medication change. The drugs are quite powerful and subtly change mood and thinking patterns. I am sure that it will pass once the medication levels even out in your system. Sometimes I think the medication makes things worse.
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Palis
post Oct 2 2007, 11:34 AM
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QUOTE(Beanchop99 @ Aug 21 2007, 07:29 PM) *
Welcome to the Wellbutrin forum!

Please tell us a little about yourself.


Hello. I am new to this forum. I recently started taking WellbutrinXL. My doc had me on 150 mg for 2 wks and then increase to 300mg. I had a lot of side effects in the first week and a half but they seemed to go away. After increasing to 300 mg I felt kind easy to anger. Thinking I should back the dose back to 150mg. ?? Also recently I am experiencing horrible allergic reaction with dairy. I have been sensitive to it from time to time but nothing like this... sharp pains, sweats, vomiting.... Has anyone else had this issue with dairy and Well..XL?
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Burgy
post Oct 2 2007, 11:48 AM
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welcomeani.gif to DF, Palis!

I'm on Wellbutrin XL 300 mg, too. I've been on it for several months, and it's completely smoothed out for me. But I agree, the first 8 weeks, and especially the first 4, can be an emotional rollercoaster. I actually took 150 mg for the full 8 week startup period, to see if that was enough. I recommend that to people, because 300 mg can be too intense for some people. But of course, you should talk to your doctor and follow his/her instructions. Most ADs, including WB, will heighten your sensitivity to other things. So if you had a mild food allergy before, you might need to avoid that food altogether, and least for several weeks. Some people have an allergic reaction to the WB itself and have to stop, but your situation doesn't sound like that. Read the WB drug fact sheet on their website, and if you develop any of the severe allergic reactions that are listed, stop the WB and get medical attention right away.

The thing I like about WB is that it doesn't dampen the emotions like SSRIs can. It brightens them, and even enhances them. It's a mostly positive experience for me, but I have noticed sharper anger sometimes, and more of a tendency to cry over something sentimental. I like this, because I want the full range of emotions, but I don't want to be depressed. With WB, I can feel it all, then return to neutral like a "normal" person, instead of being dragged down into depression all the time. WB does nothing for anxiety, and may even exacerbate an anxiety disorder, so some people add an SSRI to it. I keep my anxiety in check through exercise and meditation.

Welcome aboard, and please keep us posted!


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mssjanine
post Oct 3 2007, 06:40 PM
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Hi all, I'm back to taking Wellbutrin tomorrow. It's been over a year since I've taken it. I started on it in early 2006 and stayed on it for 4 or 5 months. I started feeling so good that I stopped taking it. Yeah, it's not a good idea to take yourself off meds without your doctor's consent.

I've been down lately, plus my best friend recently passed away, so my pdoc and I decided I should go back on the Wellbutrin. I'm not looking forward to the start up side effects I experienced last time (anxiety, intense emotions, difficulty sleeping), but my pdoc gave me some Ambien and Xanax, so hopefully those will ease the transition.

This post has been edited by mssjanine: Oct 3 2007, 06:47 PM
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teripec
post Oct 3 2007, 06:45 PM
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QUOTE(Beanchop99 @ Aug 21 2007, 08:29 PM) *
Welcome to the Wellbutrin forum!

Please tell us a little about yourself.



i took wellbutrin for awhile but not alone now adays docs mix meds. trying to find that perfect cocktail for depression , bi-polar and what not, i needed it added so that it would counter the meds that tend to cause wieght gain but wellbutrin can increase anxiety, i found i never cut down on my smoking though.
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luvanimals
post Oct 4 2007, 12:19 AM
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Hi everyone, My pdoc just prescribed wellbutrin for me as the Zoloft that I've been taking for 7 years seems to be pooping out a little bit. My diagnoses are OCD, GAD, and depression. The Zoloft still seems to be keeping my OCD in check but since my depression and anxiety have ramped up a bit lately, my pdoc wanted to add wellbutrin.

I've gone through the "adjustment period" on different drugs before, but this one is a doozy. I've only had 4 doses, and as of last night my moods began swinging from tears to fury in a matter of seconds. It also is making me very sick to my stomach. I can't seem to stay out of the bathroom, so to speak. I feel only a bit jittery, but have noticed that my anxiety level seems to be on the rise. I'm really trying to avoid using my ativan, and so far so good--no full blown panic attacks yet.

I am hanging in there and hoping that things don't get much worse. I do hope that this new Zoloft/wellbutrin combo works eventually. I just wish that the side effects would level out already!


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post Oct 4 2007, 06:54 PM
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QUOTE(luvanimals @ Oct 4 2007, 01:19 AM) *
Hi everyone, My pdoc just prescribed wellbutrin for me as the Zoloft that I've been taking for 7 years seems to be pooping out a little bit. My diagnoses are OCD, GAD, and depression. The Zoloft still seems to be keeping my OCD in check but since my depression and anxiety have ramped up a bit lately, my pdoc wanted to add wellbutrin.

I've gone through the "adjustment period" on different drugs before, but this one is a doozy. I've only had 4 doses, and as of last night my moods began swinging from tears to fury in a matter of seconds. It also is making me very sick to my stomach. I can't seem to stay out of the bathroom, so to speak. I feel only a bit jittery, but have noticed that my anxiety level seems to be on the rise. I'm really trying to avoid using my ativan, and so far so good--no full blown panic attacks yet.

I am hanging in there and hoping that things don't get much worse. I do hope that this new Zoloft/wellbutrin combo works eventually. I just wish that the side effects would level out already!



Hi Luv!!

Hmmm. What dosage are you on? If you are feeling sick to your stomach since you took them, I think you should call your doctor. See what he says. Maybe he will lower the dose or whatever. I take Wellbutrin with Xanex because of the anxiety effects of W. I also take Paxil at night along with a Xanex. Everyone is different. I know you know that. This combo works great for me, except I am having short term memory loss. So Im going to the doc tomorrow to tell him. I put off telling him because I feel so good. I think you shouldnt put off calling him. You may adjust just fine, but call him anyway, he needs to know. Gentle Sun


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jillyo
post Oct 5 2007, 02:08 PM
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QUOTE(lambvet @ Sep 28 2007, 10:52 AM) *
QUOTE(jillyo @ Sep 28 2007, 07:35 AM) *
Yo.

Well, I'm on my third day on Wellbutrin XL (150 mg). So far I've noticed it's given me an attitude. That's about it. I know I have to wait for about 8 weeks for it to truly kick in, but dang I'm impatient. But I did notice a good thing right away. It made me more alert. When I was on Zoloft, I was draggin big time. I'm also taking Depakote. Oh, quick question: I've been brusing very easily. Is that a side effect of Depakote?

Alrighty, TTYL!


Hi Jillyo,

You should talk to your doctor soon, Depakote may be involved but you really should disclose this type of concern for an accurate assessment of how you could be reacting to any medication. Our meds can have a variety of SEs, even those that are rare and you might not usually hear about. Years ago, although I am probably much older than you and have a history of alcohol abuse, but again, years ago, the pDoc I had back then suspected that I might be BP, since then NOT, but at the time she had me take a liver test and then checked my liver every 8 weeks until I finally changed to gabapentin. I never had any liver abnormalities, but sometimes Depakote can cause them. So she just wanted to be safe because of my history. So definitely let your doc know about your bruising if it is abnormal. Good advice for any abnormality you might notice with any med.

Peace and Love.... wayne




Wayne,

Yeah, I've been keeping an eye on my bruising. When I see the doc soon, I will ask her about that as well as the Liver issue. Good to know. Thanks! I've also been slowly lowering my alcohol intake. I'm not gonna quit entirely, but I've been meaning to slow it down for a while (Became dependant on it to forget bad memories). It's taken me a few years, but I've finally been able to limit my drinking to just the weekends and am now able to politely say "no" if an offer of going out comes along during the week.

Anyhoo, the Wellbutrin XL is doing well for me. I have my energy back, and I'm able to keep my place organized and clean again without going ballistic on my fiance for leaving things outta place. I'm beginning to care about things again. Gosh it's been a while. The only problem I'm trying to work on now is getting my love lust back. I know it takes about 8 weeks for the drug to show it's work on me, so I'm hoping it'll help my mojo out as well. That's one of the main reasons why my doc had me switch from zoloft to Wellbutrin XL. She origonally wanted to keep me on the zoloft as well, but I said that I wanted to try out the Wellbutrin on its own with my Depakote first. So far, so good.

I must admitt, though, I'm a bit nervouse when I get my spurts of energy now. That's how I used to be. But this time, I have it without the angry reprocussions I once had. Maybe I'm being me again. The real me. And the bad parts are no more. It's hard to tell, y'know? I really don't know who I am anymore. I'm just going by feelings. I don't have a certain "look" to guide me to a personality, or I don't listen to "certain music" to help my identity. I've always been left to center I guess. That's what makes it a little tough to remember what I was like before I went nuts. I was younger than I am now, so I can't act like I used to. I'm wiser, too. Well, I guess only time will tell. Thanks for letting me vent. Holla!
computer.gif
-Jill
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lambvet
post Oct 6 2007, 02:59 PM
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QUOTE(jillyo @ Oct 5 2007, 12:08 PM) *
QUOTE(lambvet @ Sep 28 2007, 10:52 AM) *
QUOTE(jillyo @ Sep 28 2007, 07:35 AM) *
Yo.

Well, I'm on my third day on Wellbutrin XL (150 mg). So far I've noticed it's given me an attitude. That's about it. I know I have to wait for about 8 weeks for it to truly kick in, but dang I'm impatient. But I did notice a good thing right away. It made me more alert. When I was on Zoloft, I was draggin big time. I'm also taking Depakote. Oh, quick question: I've been brusing very easily. Is that a side effect of Depakote?

Alrighty, TTYL!


Hi Jillyo,

You should talk to your doctor soon, Depakote may be involved but you really should disclose this type of concern for an accurate assessment of how you could be reacting to any medication. Our meds can have a variety of SEs, even those that are rare and you might not usually hear about. Years ago, although I am probably much older than you and have a history of alcohol abuse, but again, years ago, the pDoc I had back then suspected that I might be BP, since then NOT, but at the time she had me take a liver test and then checked my liver every 8 weeks until I finally changed to gabapentin. I never had any liver abnormalities, but sometimes Depakote can cause them. So she just wanted to be safe because of my history. So definitely let your doc know about your bruising if it is abnormal. Good advice for any abnormality you might notice with any med.

Peace and Love.... wayne




Wayne,

Yeah, I've been keeping an eye on my bruising. When I see the doc soon, I will ask her about that as well as the Liver issue. Good to know. Thanks! I've also been slowly lowering my alcohol intake. I'm not gonna quit entirely, but I've been meaning to slow it down for a while (Became dependant on it to forget bad memories). It's taken me a few years, but I've finally been able to limit my drinking to just the weekends and am now able to politely say "no" if an offer of going out comes along during the week.

Anyhoo, the Wellbutrin XL is doing well for me. I have my energy back, and I'm able to keep my place organized and clean again without going ballistic on my fiance for leaving things outta place. I'm beginning to care about things again. Gosh it's been a while. The only problem I'm trying to work on now is getting my love lust back. I know it takes about 8 weeks for the drug to show it's work on me, so I'm hoping it'll help my mojo out as well. That's one of the main reasons why my doc had me switch from zoloft to Wellbutrin XL. She origonally wanted to keep me on the zoloft as well, but I said that I wanted to try out the Wellbutrin on its own with my Depakote first. So far, so good.

I must admitt, though, I'm a bit nervouse when I get my spurts of energy now. That's how I used to be. But this time, I have it without the angry reprocussions I once had. Maybe I'm being me again. The real me. And the bad parts are no more. It's hard to tell, y'know? I really don't know who I am anymore. I'm just going by feelings. I don't have a certain "look" to guide me to a personality, or I don't listen to "certain music" to help my identity. I've always been left to center I guess. That's what makes it a little tough to remember what I was like before I went nuts. I was younger than I am now, so I can't act like I used to. I'm wiser, too. Well, I guess only time will tell. Thanks for letting me vent. Holla!
computer.gif
-Jill


Hi Jill,

Glad to hear that and I hope the bruising resolves soon or you find out its cause. And it sounds as if things are improving for you as well. As an aside, concerning sexual dysfunction, there are the well known meds for ED for men that work for women as well. If everything else is going well on your meds other than that, you might look into them as a way to overcome this VERY ANNOYING SE, lol.

Hope to hear back from you soon on your doctor's appt. and how your liver enzymes are doing and I hope that you can find some resolution to your bruising.....

Peace and Love... wayne

Sabbat Shalom


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(if you have any questions about your care or treatment, please contact your Doctor or Therapist for advice,
those of us here on DepressionForums are here as your personal peer support system.)


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mssjanine
post Oct 8 2007, 10:32 AM
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I'm just a few days into taking Wellbutrin SR and I've already noticed a lifting of the "depression fog". I feel a liitle more alert and just in a better mood.
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gottafeelbetter
post Oct 14 2007, 04:23 PM
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QUOTE (mssjanine @ Oct 8 2007, 11:32 AM) *
I'm just a few days into taking Wellbutrin SR and I've already noticed a lifting of the "depression fog". I feel a liitle more alert and just in a better mood.

Hi

I started wb 150 xl four days ago. I felt really heavy headed shocked.gif the first day. But since I have felt ok as far as SE's go. I definitely feel better as far as general well being. I have never taken anything like wb. But since I've been on it, I realize just how tough life was and that it doesn't HAVE to be that way. I function really well, have lots of friends, own a successful business and am married to a wonderful DH with a beautiful DD. I guess the only way to describe how I used to feel (WB's helping) is dread. I dreaded to write out bills, I dreaded to do laundry, I dreaded to answer the phone and sometimes (I'm ashamed to say) I dreaded to even play with my DD. shocked.gif I try to be a positive person in all I do and didn't want to even admit that I felt this way. I tried for several years as it worsened to act like it didn't exist but all I did was eat too much to deal with it and make myself feel like I would explode inside. My doc finally asked me about taking wb while we were discussing my weight issues and I burst into tears and told her how completely overwhelmed I feel. She suggested trying WB for that. Now, I really do think that I needed something to change what was going on in my head and my body.

Wish me luck!

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gottafeelbetter
post Oct 14 2007, 04:26 PM
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Also, has anyone else found that they sleep BETTER with WB? I know that seems to be odd but true for me. I have also had a dull headache alot, anyone else? How long before it stopped? It's annoying.
'
Thanks!
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gottafeelbetter
post Oct 14 2007, 04:53 PM
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I just read that there is a WB xl in generic, is that right? The pharmacy didn't mention this and my pharmacy usually does. I'm also surprised my doc didn't mention it. Does it work the exact same?
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gottafeelbetter
post Oct 14 2007, 06:04 PM
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Ok, just one more question - maybe. lol I take Claritin and have taken some aleve. Is that ok with wb? Is tylenol, ibuprophen ok? I haven't seen any info on interactions with these, just trying to make sure.

Thanks!
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Burgy
post Oct 14 2007, 06:49 PM
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welcomeani.gif to DF, and the WB forum, gottafeelbetter!

I'm so glad to hear that WB is working so well for you. I'm on it, too, and I love it. It's very brightening and motivating. Now to answer your questions...

I have also found that I sleep better on WB, and I've heard that from others too. Some people get insomnia from it, but I actually get worse insomnia from SSRIs, which are supposed to be calming! Kind of a weird paradox there. I also had headaches for a couple of weeks, but it went away. I would suggest reducing or avoiding caffeine to help with that.

At this time, only the 300 mg XL is offered in generic form. Soon there will be a 150 mg generic pill, too. I take the generic bupropion XL 300 mg. It works well for me, but some people have trouble with it. It releases faster than the name brand, so you might feel a spike in energy, then a crash later in the day. I felt a little weird for a few days after switching to generic, but I adjusted in about a week. I've been on the generic 300 XL for a few months now, and it feels very smooth to me. My energy is pretty consistent throughout the day. So you wont know if generic works for you until you try it, and give your body some time to adjust.

As far as I know, allergy medicine and OTC pain killers are just fine while taking WB. But to be sure, you should visit their website and read their literature about that. I haven't had any problem with allergy medicine, antibiotics, or pain killers. I recently had a root canal, and I had no problem with the nitrous oxide tongue.gif , but the novocaine made me feel a little weird. Novocaine contains epinephrine (adrenaline), and that, coupled with WB which increases norepinephrine (noradrenaline) and dopamine, can increase your pulse and blood pressure and make you feel pretty jacked up for a while. But I'll take that over head-cracking tooth torture pain anyday!


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gottafeelbetter
post Oct 15 2007, 08:04 AM
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Thank you for answering my questions and taking the time to welcome me! I really appreciate it! I am drinking probably 4 or 5 cans or Dt. Mt. Dew during the course of the day or if I'm working a couple of teas with meals and a couple of cans of Dt. mt. Dew at night. That might be contributing to headaches. Is there any other problems associated with caffeine intake and WB?

Thanks again!
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Burgy
post Oct 15 2007, 10:44 AM
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QUOTE (gottafeelbetter @ Oct 15 2007, 06:04 AM) *
Thank you for answering my questions and taking the time to welcome me! I really appreciate it! I am drinking probably 4 or 5 cans or Dt. Mt. Dew during the course of the day or if I'm working a couple of teas with meals and a couple of cans of Dt. mt. Dew at night. That might be contributing to headaches. Is there any other problems associated with caffeine intake and WB?

Thanks again!

I thought Mt. Dew was caffeine free...hmmm. I haven't had one of those in decades! But anyway, try to drink a lot of water. WB can be dehydrating, and that will contribute to headaches, too.

Some people do fine mixing WB and caffeine, but some react terribly, even get anxiety attacks. I'm sort of in the middle. Caffeine will raise my blood pressure and sometimes make me irritable, which I am now, because I'm drinking caffeinated tea! Duh...you'd think I'd know better. But caffeine is hard to kick.


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gottafeelbetter
post Oct 15 2007, 04:16 PM
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Thanks for the info. I got some caffeine free drinks when I went to the store today and I'm also gonna drink more water. Thanks!
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Jamielove21
post Oct 16 2007, 05:05 AM
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At what poing to you start to feel better? I was on Paxil for 7 years and switched to Wellbutrin in hopes of some help in weightloss. I have weined of the Paxil, and been on the Welbutrin for almost 4 weeks. The last 2 weeks I have had this overwhelming depression. LOTS of crying, and while I am functioning, I do not feel like myself. Does it get better or should I think about trying something else?
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lambvet
post Oct 16 2007, 05:22 AM
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QUOTE (Jamielove21 @ Oct 16 2007, 03:05 AM) *
At what poing to you start to feel better? I was on Paxil for 7 years and switched to Wellbutrin in hopes of some help in weightloss. I have weined of the Paxil, and been on the Welbutrin for almost 4 weeks. The last 2 weeks I have had this overwhelming depression. LOTS of crying, and while I am functioning, I do not feel like myself. Does it get better or should I think about trying something else?


Hi Jamie, welcomeani.gif to DF,

Well for starters you have changed from a med that controlled your serotonin to one that works on nor-epinepherine and dopamine. A med can take up to 8 weeks to work although many have reported a more immediate effect with WB.

So, if serotonin is the neurotransmitter that you need help from, then you may have to try a SSRI as well. Or, even though you weaned yourself, it was too fast in the longer run. And lastly, you may be between med efficacy and when WB kicks in fully, you will be fine.

So the best advice you could take is to call and talk with your doctor, explain what is happening and hopefully he will have an answer that will address your needs more quickly.

Thanks for posting your concerns, you will find our members both caring and supportive. And again welcomeani.gif , I hope you find DF as supportive and informational as I have since I joined here.


BE Peace and BE Love..... wayne


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nmrz
post Oct 18 2007, 09:23 AM
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hi people

how are yall doing?
i joined this forum today, since here in holland, there is not much information about wellbutrin.
im taking wellbutrin XR, ive read that its identical to XL in the USA.
since today im taking 300mg, and im doing good so far, no side effects yet.
whats weird is that this morning i went to the bathroom and there was a little pill in my stool, so i was reading on the internet and it says its normal, but im not sure how long after youve taking the pill, it can be in your stool?
cause i took it this morning around 9am, and i found the pill around 11am.
it could be that it was from yesterday but i find that hard to believe.
maybe someone can help me out.
anyways ill post and read this forum more often now
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Toronto33
post Oct 19 2007, 01:53 AM
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Hi people,

I posted a few months back about my situation if any of you want to look back. It's probably not necessary though.

Anyway, just an update...I've now bee on 150mg of Wellbutrin since early July. In general, it's worked pretty well. My main issues at the time were depressed feelings, feelings of failure, constant headaches, some stomach upset and general sleeping disorders. Wellbutrin seems to have cleared most of that up, especially the headaches which were really doing a number on me. They have absolutely vanished which is wonderful. I really feel the Wellbutrin kicked-in big time around week #6 and has been holding steady since.

What isn't so wonderful is that I've developed a new problem Or a problem I was having has grown. I'm not sure if it's because of the Wellbutrin or not, but it seems like I've developed some form of IBS (irritable bowel syndrome). I'll try not to get into too many details, but in general, my intestines are playing a symphony of noises throughout the day. Bowel movements aren't very regular and I sometimes have to go with very short notice. Stools look fairly normal, but I'm also dealing with excessive amounts of gas. Sometimes as many as 20 passes an hour! Most of these issues are very new to me and most developed around the time I started taking Wellbutrin and have only got worse since. My doctor doesn't seem to think it's the Wellbutrin as it's not a common side-effect (or so he says), but I can't help but wonder.

Apparently IBS and depression are often very much linked, so maybe I've just developed it while everything else seems to be getting better slowly, but surely. Most days I'm in quite a bit of discomfort and it's starting to effect both my relationship with my partner and my desire to be out socially (which is likely enough to send me back into depression).

So I'm pretty worried. If anyone can provide any help/guidance I'd be very much indebted!

Cheers!

This post has been edited by Toronto33: Oct 19 2007, 01:56 AM
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dreamwolf
post Oct 21 2007, 01:22 PM
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Hello,

I was looking to start a new topic in relation to positive experiences with the Wellbutrin Generic, Teva's Budeprion SR 150. I took this during May of this year and am concerned about possible neurotoxic effects of the drug.


So please let me know if you've used this without any cognitive side effects.

Thank you!
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lambvet
post Oct 21 2007, 01:46 PM
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QUOTE (dreamwolf @ Oct 21 2007, 11:22 AM) *
Hello,
I was looking to start a new topic in relation to positive experiences with the Wellbutrin Generic, Teva's Budeprion SR 150. I took this during May of this year and am concerned about possible neurotoxic effects of the drug.
So please let me know if you've used this without any cognitive side effects.
Thank you!


Hi DW,

Virtually anything we take that is psycho-active (ie. alcohol) is potentially neurotoxic, and none of the typical Ad's are any more dangerous than any other drug. SE's are listed when they cause any side effect inside the range of 1 per thousand and inside of 1 per 100 if serious enough. Millions of people are now taking bupropion on a daily basis without neurotoxic effects. In fact, under the right conditions oxygen is neutoxic!!!

Many here and otherwise use this med without any (I assume you mean neg.) cognitive SEs.


Peace and Love... wayne


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dreamwolf
post Oct 21 2007, 03:45 PM
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QUOTE
Hi DW,

Virtually anything we take that is psycho-active (ie. alcohol) is potentially neurotoxic, and none of the typical Ad's are any more dangerous than any other drug. SE's are listed when they cause any side effect inside the range of 1 per thousand and inside of 1 per 100 if serious enough. Millions of people are now taking bupropion on a daily basis without neurotoxic effects. In fact, under the right conditions oxygen is neutoxic!!!

Many here and otherwise use this med without any (I assume you mean neg.) cognitive SEs.


Peace and Love... wayne


Your point is taken - but at the same time does not provide any additional reassurance. With SSRIs and many other psychoactive drugs I would tend to agree that there is little in the way of neurotoxic potential (excepting amphetamine, amphetamine-related, and benzos) SSRIs even have been demonstrated to increase neurogenesis and have neuroprotective properties - discounting some of the studies done on animals at ultra-high doses that caused axons to become deformed.

At any rate - my concerns probably relate to knowing too much. My concerns center around certain 'chemicals' that wellbutrin degrades into/or is metabolized into and the closer similarities of these compounds to known neurotoxins. Extensive research has not been able to uncover materials to assuage the concerns in relation to these compouds in particular. Anecdotal reports on the internet for Wellbutrin are overwhelmingly negative in comparison to other drugs - i.e. Cymbalta (duloxetine). In addition I have uncovered more negative anecdotals in relation to the Teva generic budeprion.

Given - I have many things in my life which could lead to me being anxious or clinically depressed. All of these things also happened about the same time I started taking budeprion SR 150. During the month of may which I took the drug I seemed to become progressively worse - suffering from memory loss in many aspects and heightened anxiety. After tapering and withdrawing things became worse with the addition of panic attacks and difficulties sleeping. I have suffered from depression before - but never have I felt this bad. In summary it is like my own personal hell experiencing a seeming reduction in my abilities and a near loss of enjoyment of things. (like I'm in a fog and don't enjoy anything)

In order to get over my concerns I just need to speak with others that have taken the Teva budeprion SR 150 (once a day or multiple times a day - or any other teva budeprion SR dosage). Once this in accomplished I can begin to address my depression/anxiety in earnest - knowing that there is a 'recovery'.

I am seeing a neuropschyc currently whom has placed me back on Cymbalta. Curiously - he has not diagnosed me with depression - only GAD, OCD, and I believe one or two other things. My condition has improved very, very slowly in the months since May. My memory is very slowly starting to increase.

I want to know that indeed there is a light at the end of the tunnel.

Thank you.
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Burgy
post Oct 21 2007, 04:02 PM
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QUOTE (dreamwolf @ Oct 21 2007, 11:22 AM) *
Hello,

I was looking to start a new topic in relation to positive experiences with the Wellbutrin Generic, Teva's Budeprion SR 150. I took this during May of this year and am concerned about possible neurotoxic effects of the drug.


So please let me know if you've used this without any cognitive side effects.

Thank you!

QUOTE (dreamwolf @ Oct 21 2007, 01:45 PM) *
In order to get over my concerns I just need to speak with others that have taken the Teva budeprion SR 150 (once a day or multiple times a day - or any other teva budeprion SR dosage). Once this in accomplished I can begin to address my depression/anxiety in earnest - knowing that there is a 'recovery'.

Hi dreamwolf, and welcomeani.gif

I've taken Teva's Budeprion XL 300mg for several months now, and it has done wonders for me. It's an excellent antidepressant, and very activating. My depression was very dark and stagnant, so I needed something to get me up, energized, and motivated.

The only cognitive side effects I've had have been positive...greater clarity, focus, and memory...and more mental and physical energy.


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Meikos
post Oct 21 2007, 08:24 PM
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Hello,

I've been on the forums about 4-5 days and decided to stop over. I've been on Budeprion SR 150mg since October 9th. I have once major concern regarding any anti-depressant. I've heard so many stories about people becoming addicted to anti-depressants. So far, I haven't noticed a great deal of change on WB, but I will be doubling my daily dose come Tuesday. I was just stopping over to see what others thought about my concerns.
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lambvet
post Oct 21 2007, 09:13 PM
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QUOTE (Meikos @ Oct 21 2007, 06:24 PM) *
Hello,

I've been on the forums about 4-5 days and decided to stop over. I've been on Budeprion SR 150mg since October 9th. I have once major concern regarding any anti-depressant. I've heard so many stories about people becoming addicted to anti-depressants. So far, I haven't noticed a great deal of change on WB, but I will be doubling my daily dose come Tuesday. I was just stopping over to see what others thought about my concerns.


Hi Meikos. welcomeani.gif to DF

You Unix, me Cocoa... LOL One of your WB users will be right with you.

I hope you find DF as caring, supportive and informational as I have since I joined. Read around, there is a wealth of info on WB here.


Peace and Love... wayne


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(if you have any questions about your care or treatment, please contact your Doctor or Therapist for advice,
those of us here on DepressionForums are here as your personal peer support system.)


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LaraNYC
post Oct 21 2007, 09:28 PM
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Hi There,

A week ago I was diagnosed by my psychiatrist with atypical depression. This was my first visit to a psychiatrist as this depression has been slowly creeping up and consuming me for the past 1-2 years. I see a wonderful therapist and wanted to start medication in an effort to take action and get my life back.

So, I started Wellbutrin XL at 150mg last week (6 days so far). The first couple of days I felt pretty much okay, some nauseau and upset stomache and minor headaches that would come and go. Today I got hit with a pretty awful migraine. I'm not totally sure it's migraine but from what I've researched it seems to be the case:

sensitivity to light
difficulty focusing my eyes
a constant sensation that my head is cloudy and feeling of pressure.

I also feel a bit dizzy and anxious. I'm jumpy and have had a cold sweat/felt feverish all day.

I do feel a bit more depressed today but maybe that is because I am scared that this drug isn't going to work. That trying others will be hard. Today I worried if I'll ever feel better... I know that sticking it out is a good idea, but I cannot function if this migraine continues.

Do the side effects get better or worse after the first week?

I am going to call my doc first thing in the morning tomorrow. I was just curious about other people's experiences or thoughts.

Thanks!,
Lara
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Burgy
post Oct 21 2007, 09:35 PM
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Hello again, Lara.

The first two weeks are the worst with any AD. Wellbutrin can make you feel jumpy and achy and foggy for a while, but it's temporary. The 2 week mark is usually when the side effects start to fade and the positive effects start to show up. By 8 weeks you should be fully adjusted. I know it's unnerving, but you have to be patient. Don't give up too soon, or you'll never know how the drug could've worked for you.


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lambvet
post Oct 21 2007, 09:49 PM
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QUOTE (LaraNYC @ Oct 21 2007, 07:28 PM) *
Hi There,
A week ago I was diagnosed by my psychiatrist with atypical depression. This was my first visit to a psychiatrist as this depression has been slowly creeping up and consuming me for the past 1-2 years. I see a wonderful therapist and wanted to start medication in an effort to take action and get my life back.
So, I started Wellbutrin XL at 150mg last week (6 days so far). The first couple of days I felt pretty much okay, some nauseau and upset stomache and minor headaches that would come and go. Today I got hit with a pretty awful migraine. I'm not totally sure it's migraine but from what I've researched it seems to be the case:
sensitivity to light
difficulty focusing my eyes
a constant sensation that my head is cloudy and feeling of pressure.
I also feel a bit dizzy and anxious. I'm jumpy and have had a cold sweat/felt feverish all day.
I do feel a bit more depressed today but maybe that is because I am scared that this drug isn't going to work. That trying others will be hard. Today I worried if I'll ever feel better... I know that sticking it out is a good idea, but I cannot function if this migraine continues.
Do the side effects get better or worse after the first week?
I am going to call my doc first thing in the morning tomorrow. I was just curious about other people's experiences or thoughts.
Thanks!,
Lara


Hi Lara, welcomeani.gif to DF,

Ditto to what Burgie had to say, both generically with ADs in general and specific to yours. But WB is a tad more energizing than the others and sometimes works faster than others but everyone it different. You calling the doc tomorrow is a good thing, your best advice will always come from there.

Again welcomeani.gif and I hope you find our membership caring and supportive and our/your site informative....


BE Peace and BE Love.... wayne


--------------------
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(if you have any questions about your care or treatment, please contact your Doctor or Therapist for advice,
those of us here on DepressionForums are here as your personal peer support system.)


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chinkes
post Oct 21 2007, 11:05 PM
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QUOTE (suburgatory @ Oct 14 2007, 03:49 PM) *
welcomeani.gif to DF, and the WB forum, gottafeelbetter!

I'm so glad to hear that WB is working so well for you. I'm on it, too, and I love it. It's very brightening and motivating. Now to answer your questions...

I have also found that I sleep better on WB, and I've heard that from others too. Some people get insomnia from it, but I actually get worse insomnia from SSRIs, which are supposed to be calming! Kind of a weird paradox there. I also had headaches for a couple of weeks, but it went away. I would suggest reducing or avoiding caffeine to help with that.

At this time, only the 300 mg XL is offered in generic form. Soon there will be a 150 mg generic pill, too. I take the generic bupropion XL 300 mg. It works well for me, but some people have trouble with it. It releases faster than the name brand, so you might feel a spike in energy, then a crash later in the day. I felt a little weird for a few days after switching to generic, but I adjusted in about a week. I've been on the generic 300 XL for a few months now, and it feels very smooth to me. My energy is pretty consistent throughout the day. So you wont know if generic works for you until you try it, and give your body some time to adjust.

As far as I know, allergy medicine and OTC pain killers are just fine while taking WB. But to be sure, you should visit their website and read their literature about that. I haven't had any problem with allergy medicine, antibiotics, or pain killers. I recently had a root canal, and I had no problem with the nitrous oxide tongue.gif , but the novocaine made me feel a little weird. Novocaine contains epinephrine (adrenaline), and that, coupled with WB which increases norepinephrine (noradrenaline) and dopamine, can increase your pulse and blood pressure and make you feel pretty jacked up for a while. But I'll take that over head-cracking tooth torture pain anyday!

Hi there Suburgatory!
I'm wondering here... As you may recall, I'm on WB150XL for almost three months now. I had a dental procedure the other day and as he shot me up with novacaine I felt a pain go down the right side of my neck into the right side of my chest. It felt like horrid indigestion. I told him about it and he had no clues. It lasted until the novacaine wore off. I never even thought about WB interfering. I also have tachycardia, which I always tell the dentists about because too much novacaine can trigger an attack. I normaly take a little extra beta blocker before dental procedures just in case. I thought he must have given me too much novacaine, but now I wonder if it wasn't an neg. interraction with WB. I told the doc if it had been a pain on the left side, I would have had such a panic attack, they would have had to call an ambulance in!!!
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zippo
post Oct 24 2007, 04:21 PM
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Hi all smile.gif

A little history first. Diagnosed with depression and social anxiety. Tried some of the SSRI's and they just don't work for me. Advocated for myself with the pdoc and talked him into letting me try Wellbutrin. He didn't seem to be thrilled about the idea but went along.

Have the generic manufactured by Teva, 150 mg sr. Generics don't seem to bother me.

Day one, took 1 about lunch time, felt just a bit agitated but certainly not overwhelming. No increased anxiety, no real effects in any other area.

Day two, took one in the am before work. Not agitated today but a minor headache most of the day, no increased anxeity, no other significant results. I was only supposed to take 1 pill for 7 days and then ramp up to twice daily. Seeing how the side effects have been minimal I decided to take another one today and see how it goes. Will drop back to 1 a day if any problems arise.


Well that's about it for now.

Good luck to all that are searching and good on the ones that have already found.

Later,

Zippo

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Sheepwoman
post Oct 25 2007, 12:10 PM
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Welcome to DF, zippo,
You are having some mild SE's and I bet some people are envious of that.

As far as your dosing, there is reasoning to start you off at one pill a day. It takes the body a bit of time to adjust to any new med and taking the full dose can sort of put things out of whack. Follow your pdoc's dosing instructions and don't vary from it. Initially with any new med, you can expect some sort of reaction-like you became aggitated the first day. You may experience some ups and downs with your moods, too. The keyword is to be patient as it can take up to 8 weeks to receive the full benefits of WB.
Sheepwoman baaa.gif


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PhoenixFire
post Oct 25 2007, 04:16 PM
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Hello! yay.gif

My name is Kim i just started on wellbutrin xl 150 mg ive got a few more days until i start twice daily... and im really nervous. I dont know what it is but i have always avoided anti depressants for various reasons.... cant tell whats more scary... the thought of this not helping me...or the thought of it working...
im scared about long term effects and what will happen when i loose my job in a few months (company merger) i certainly wont be able to afford it. so what then?.... from everything ive read you have to taper off.
sigh i dont know... blue day i suppose. anxious to find out what life is like on the other side. dont get me wrong. i smile i laugh i have a grand ol time too. just always some underlying weight driving me crazy
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