I have been on and off anti-depressants for years. Tried Paxil and it made me gain weight and become jittery, lexapro worked great until my insurance refused to cover it, then i started cymbalta and gained 60 lbs and it barely worked. I recently started zoloft and gained some more weight so my dr. added wellbutrin sr to my daily meds. I take 150 mg of wellbutrin sr in the morning and 50 mg of zoloft before bed. So far, so good, however, i have not noticed any weight loss like my dr. told me to expect. I have been on the wellbutrin/zoloft together for 9 days now and am eating a lot less because all of my sugary cravings are gone. However, even though my weight has stayed the same, i have not lost an ounce. For those of you that ate less on wellbutrin, how long before you noticed weight loss? it's so tough having all of this extra weight!

Hi sarbear, I can't directly answer your question because I haven't been on that combination. I wanted to remind you that 9 days is not very long. The wellbutrin hasn't even fully kicked in. I'd say that you need to give it a good 4-6 weeks before you can really expect to see much difference. If you start to lose before then, that's an added bonus.
I'm glad that your doctor has so much confidence in the weight loss. I'm just wondering if wellbutrin will cause you to lose weight or make it easier to lose weight. I'm glad that at least you aren't continuing to gain!
Iowa