How long did Zoloft take to work on all of you?

I voted 4 weeks, because that is when the zoloft seemed to be working fully for me. However, I did notice slight improvement within the first week - kind of just a feeling that things were starting to lighten up. Could have been more of a placebo effect or just relief from knowing I was getting help. Anyway, it took about 1 month for me to feel like it was really doing something.

I too noticed a difference after 1 week. However, it wasn't until 5-6 weeks that I felt more like 'my ol' self'. The biggest difference after one week was feeling like I could bounce back from things more quickly.

This post has been edited by PapaQ: Nov 23 2005, 10:16 PM

Took me 6 weeks at a huge dosage (400 mg). Then again, I had what the doctor said was the most severe case of depression she'd ever seen. . .

I was taking prozac for 5 months before starting zoloft. I found that within the first few days I was feeling back to my old self. I am hoping that it will get better as I keep taking them.

Good luck, Clover! Keep us posted on how you are doing.

Karen

About 4 weeks.

I feel its effects almost immediately, but this time around it took 2 weeks to really kick in. Before it may have been longer or shorter that that.

o.0;; Well... After I took 1/2 of the 50mg pill... After too hours, I gotten extreme headaches, wanting to vomit, pain all over... Just MOST of the side effects you can think one. And thats like the 1st time I took it. I guess it didnt kick in now did it...

IceColdMemories,

That stinks, that you had such a violent, quick reaction to zoloft. I hope you work with your doctor to find something that will help you without all the problems!

Karen

I´ve been on zoloft for about 4 weeks, first week was on 25 mg and 3 weeks on 50mg.
I ´ve noticed little improvement after the first week but now it seems it didn´t get any better.
Seems it helping but sometimes i think it´s my imagination,it hard to tell yet if it is really working.
What do you think? is it normal?

when you say it started to kick it means that already you feel good or when you started to feel that little improvement?
How long do you think will it take to reach the full effect?

This post has been edited by chariots: Mar 12 2006, 04:06 AM

For me, there was just a teeny, tiny kick...more like a slight feeling of hope that something was going to get better...after a few days or at least within the first week of starting the med. Perhaps it was just the placebo effect, or the hope of knowing that finally I was doing something about trying to get better.

Real, noticeable improvement, though, probably took a good month for me. Everyone is SO different! It could take a couple of weeks or even (sadly) a couple of months to get the full effect of the AD. I hope you will hang in there a bit longer. Keep in touch with your doctor, and if you really are not noticing any change at all after 6 weeks at the 50mg dose, you probably want to discuss making a change.

Keep in touch!

Karen

I'm not sure if I'm remembering this completely accurately (since this was seven years ago), but I'm pretty sure it kicked in almost immediately for me. But then again, I'm an anomaly in that my body reacts amazingly quickly to any sort of medication.

I really didn't get full effect until 4 weeks. I was started on 25mg, after 2 days raised to 50mg, 3 days up to 75mg, 3 days 100mg, until I reached 150mg ( i got side effects not listed at that dose) and was then lowered to 100mg. I truly did not get the full effects until 4 weeks had passed and only recall a slight improvement at the lower doses. I had not been on an AD for 4 years, so this was an emergency start up at the hospital for me. I also had a second AD added while I was there for sleep.

I am doing well on the 100mg dose.
Sheepwoman

I am looking to take Zoloft for a more excellerated recovery to depression and SA.

Oh my... You are extreme baby! On the leaflet of Zoloft in Poland it is written that the maximum dose is 200mg. I wonder why.. Maybe because one doesn't have to take more than 200mg to get the positive effects and the bigger dose gives you only more side effects.. What do you think?