.. I have a problem over investigating things. I read online that there CAN be a drug interaction with these two. Does anyone here take it? My doctor suggested it and I was alarmed by it. My mother takes it with no problems.. I'm just a big scardy cat about meds.

Thanks.

Hello :)

I dont really know anything about this combo, but maybe you could tell your doctor about your concerns, it might help you.

HUGS
Isabeau

From RxList:
"Prozac - Interactions:
Lithium — There have been reports of both increased and decreased lithium levels when lithium was used concomitantly with fluoxetine(Prozac). Cases of lithium toxicity and increased serotonergic effects have been reported. Lithium levels should be monitored when these drugs are administered concomitantly."

Lithium is often used in unipolar depression to potentiate (increase the action of) an anti-depressant also prescribed. As you can see above, lithium will increase the effect of the Prozac (which is a Good Thing). As your lithium levels could go either up or down, in combination with Prozac, you need to have levels done often, especially at the beginning, to adjust your dosage of lithium, so it doesn't rise above therapeutic levels. This is a simple blood test.

So yeah, there is a risk, but that risk is known and measurable with precautions, and I'd consider this an acceptable risk. Your mother's reactions suggests you're likely to be okay too (sharing half her genes).

Just be sure to ask for lithium levels at regular intervals and you can see how it goes.

And learn the symptoms of lithium toxicity so you can catch any problems early.
From E-How: "Milder symptoms are nausea, vomiting and diarrhea, which can lead to involuntary muscle contractions, swelling of the legs and uncontrollable twitching of the extremities. As lithium levels increase, you will have difficulty walking, experience dizziness, blurred vision, slurred speech and an irregular pulse."

Call doc immediately if you notice any of these.

I hope I haven't scared you. There are always risks with our medications, but this risk, is one you can see coming, and if it helps you, it'll be worth it.

The best defence is being informed!

Thanks so much for the replies.

I HAVE put in a call to my doctor. The receptionist pretty much ticked me off.. she actually replied to me, "WHat does the pill bottle say.." Um.. as if I couldn't READ the directions. What my PILL bottle says and what WE discuss is TWO different things.

SO annoying.