There Is No Association Between Antidepressants And Birth Defects
Expectant mothers can safely use prescribed antidepressants during
their first trimester, according to a new study from the Université de
Montréal and Ste. Justine Hospital published in the May 2008 edition of the British Journal of Psychiatry.
Dr. Anick Bérard and her team found that antidepressants have no effect
on foetal development. "This is the first study to investigate the
impact of antidepressant use during the first trimester of pregnancy in
mothers with psychiatric disorders," she said. "In terms of birth
malformations in this population, we found no difference between women
who used antidepressants and those who did not use antidepressants
during their first trimester."
The research team used data from the Quebec Pregnancy Registry,
established by their group, to analyze the records of 2,329 new mothers
diagnosed with a psychiatric disorder and treated with antidepressants
for at least 30 days before pregnancy. Also included in the registry
were women who delivered liveborn and stillborn children, while birth
defects were considered anything from facial malformations to heart
anomalies.
"The duration of antidepressant use in the first trimester of pregnancy
was not associated with an increased risk of birth malformations,"
explained Dr. Bérard. "We hope these findings help clinicians and women
decide whether to continue antidepressant therapy during pregnancy."
Partners in research:
This study was supported by the Fonds de la Recherche en Santé du
Québec (FRSQ), the Réseau Québécois de Recherche sur l'Usage des
Médicaments and the Network for the Wellbeing of Children.
On the Web:
About the study published in the British Journal of Psychiatry
About the Université de Montréal
Dr. Bérard is an associate professor and is the Louis-Boivin Family
Chair on Medications, Pregnancy and Lactation at the Faculty of
Pharmacy of the Université de Montréal and the recipient of a career
award from the Canadian Institutes of Health Research.
Université de Montréal
About Anick Bérard
Main News Category: Depression
This article was first published May 9, 2008
Any medical information published on this website is not intended as
a substitute for informed medical advice and you should not take any
action before consulting with a health care professional.